Copper-catalyzed synthesis of 2-unsubstituted, n-substituted benzimidazoles
| Title | Copper-catalyzed synthesis of 2-unsubstituted, n-substituted benzimidazoles |
| Publication Type | Journal Article |
| Year of Publication | 2009 |
| Authors | Hirano, K, Biju, AT, Glorius, F |
| Journal | Journal of Organic Chemistry |
| Volume | 74 |
| Issue | 24 |
| Pagination | 9570–9572 |
| Date Published | NOV |
| Abstract | An efficient copper-catalyzed intramolecular arylation of formamidines forming 2-unsubstituted benzimidazoles in excellent yields is reported. Sixteen examples bearing sterically demanding substituents on nitrogen like Mes, 2,6-diisopropylphenyl, or 2-tert-butylphenyl and tolerating various functional groups demonstrate the utility of this method. |
| DOI | 10.1021/jo902160y |
| Funding Agency | Council of Scientific & Industrial Research (CSIR) - India |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 4.002 |
Divison category:
Organic Chemistry