Copper-catalyzed intramolecular N-arylation of quinazolinones: facile convergent approach to (-)-circumdatins H and J

TitleCopper-catalyzed intramolecular N-arylation of quinazolinones: facile convergent approach to (-)-circumdatins H and J
Publication TypeJournal Article
Year of Publication2010
AuthorsKshirsagar, UA, Argade, NP
JournalOrganic Letters
Volume12
Issue16
Pagination3716-3719
Date PublishedAUG
ISSN1523-7060
Abstract

A copper-catalyzed intramolecular N-arylation of a quinazolinone nucleus that furnished the central benzodiazepine core unit has been demonstrated to accomplish an efficient convergent total synthesis of (-)-circumdatins H and J.

DOI10.1021/ol101597p
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)5.250
Divison category: 
Organic Chemistry