Cholesterol-linked beta-cyclodextrin - a thermotropic liquid-crystalline derivative

TitleCholesterol-linked beta-cyclodextrin - a thermotropic liquid-crystalline derivative
Publication TypeJournal Article
Year of Publication2007
AuthorsShaikh, VAhmed Ebra, Lonikar, SVitthal, Dhoble, DArun, Pawar, GM
JournalBulletin of the Chemical Society of Japan
Volume80
Issue10
Pagination1975-1980
Date PublishedOCT
Type of ArticleArticle
ISSN0009-2673
Abstract

Liquid-crystalline derivative of ss-cyclodextrin (BCD) was prepared by covalent linking of monocholesteryl succinate (ChMS) with ss-cyclodextrin. To the best of our knowledge, this was first ever attempt so far of its kind, in which BCD has been converted into its liquid-crystalline derivative through covalent linkage of a mesogen. The degree of substitution (DS) obtained was approximate to 2.00. The product was characterized by various techniques, such as FT-IR, NMR, DSC, hot-stage-coupled optical polarizing microscopy (OPM), microanalysis and chemical methods. Cholesterol-linked ss-cyclodextrin (CDCh) derivative was found to exhibit thermotropic liquid-crystalline behavior. The product exhibited birefringence during first heating above 130 degrees C, and it became isotropic at about 180 degrees C, whereas the parent compound BCD decomposed without melting above 250 degrees C. A comparison of CDCh derivative to similar liquid-crystalline polysaccharide derivatives is presented.

DOI10.1246/bcsj.80.1975
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)1.372
Divison category: 
Polymer Science & Engineering