Chemoselective deprotection of N-allylic amines using DDQ

TitleChemoselective deprotection of N-allylic amines using DDQ
Publication TypeJournal Article
Year of Publication2014
AuthorsKumar, P, Cherian, SK, Jain, R, Show, K
JournalTetrahedron Letters
Volume55
Issue52
Pagination7172-7176
Date PublishedDEC
Type of ArticleArticle
ISSN0040-4039
KeywordsChemoselective deprotection, DDQ, N-Allylic amines, Orthogonally protected tertiary amines
Abstract

A highly chemoselective and simple method for the deprotection of N-allylic amines using DDQ has been developed. The use of DDQ in dichloromethane-water provides a mild and efficient one-step deallylation of a wide variety of orthogonally protected tertiary amine derivatives. (C) 2014 Elsevier Ltd. All rights reserved.

DOI10.1016/j.tetlet.2014.10.136
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.347
Divison category: 
Organic Chemistry