Carboxamide versus sulfonamide in peptide backbone folding: a case study with a hetero foldamer

TitleCarboxamide versus sulfonamide in peptide backbone folding: a case study with a hetero foldamer
Publication TypeJournal Article
Year of Publication2013
AuthorsRamesh, VVE, Kale, SS, Kotmale, AS, Gawade, RL, Puranik, VG, Rajamohanan, PR, Sanjayan, GJ
JournalOrganic Letters
Volume15
Issue7
Pagination1504-1507
Date PublishedAPR
ISSN1523-7060
Abstract

Strikingly dissimilar hydrogen-bonding patterns have been observed for two sets of closely similar hetero foldamers containing carboxamide and sulfonamides at regular intervals. Although both foldamers maintain conformational ordering, the hydrogen-bonding pattern and backbone helical handedness differ diametrically.

DOI10.1021/ol4002762
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)6.324
Divison category: 
Center for Material Characterization (CMC)
Central NMR Facility
Organic Chemistry