Bi(OTf)3-promoted cascade annulation of hydroxy-pyranones and unsaturated γ-ketoesters for the construction of polycyclic bridged pyrano-furopyranones
| Title | Bi(OTf)3-promoted cascade annulation of hydroxy-pyranones and unsaturated γ-ketoesters for the construction of polycyclic bridged pyrano-furopyranones |
| Publication Type | Journal Article |
| Year of Publication | 2024 |
| Authors | Rathod, AB, Borade, BR, Sambherao, PI, Kontham, R |
| Journal | Organic and biomolecular chemistry |
| Volume | 22 |
| Issue | 3 |
| Pagination | 496-500 |
| Date Published | JAN |
| Type of Article | Article |
| ISSN | 1477-0520 |
| Keywords | 1 3-Dicarbonyl Compounds, alkynols, Coumarins, Fungus |
| Abstract | An efficient protocol for constructing complex three dimensional polycyclic bridged chromano-furopyranones and pyrano-furopyranones (closely related to bioactive natural products) via bismuth(III)-catalyzed cascade annulation of hydroxy-pyranones and unsaturated gamma-ketoesters is presented. This process involves intermolecular Michael addition, intramolecular hemiketalization, lactonization, formation of one C-C bond and two C-O bonds, rings, and contiguous stereocenters. |
| DOI | 10.1039/d3ob01862h |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.2 |
Divison category:
Organic Chemistry
Database:
Web of Science (WoS)