Biomimetic total syntheses of flinderoles B and C

TitleBiomimetic total syntheses of flinderoles B and C
Publication TypeJournal Article
Year of Publication2011
AuthorsDethe, DH, Erande, RD, Ranjan, A
JournalJournal of the American Chemical Society
Volume133
Issue9
Pagination2864-2867
Date PublishedMAR
ISSN0002-7863
Abstract

A simple and efficient biomimetic synthesis of pyrrolo[1,2-a]indoles using a highly stereo- and regioselective [3 + 2] reaction cascade was developed and then further applied in the first total synthesis of flinderoles B and C, which proceeded in 17.2% yield over the longest linear sequence of 11 steps.

DOI10.1021/ja1116974
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)10.47
Divison category: 
Organic Chemistry