Bacteriophages: status quo and emerging trends toward one health approach

TitleBacteriophages: status quo and emerging trends toward one health approach
Publication TypeJournal Article
Year of Publication2024
AuthorsSamson, R, Dharne, M, Khairnar, K
JournalScience of The Total Environment
Volume908
Date PublishedJAN
Type of ArticleReview
ISSN0048-9697
KeywordsAntimicrobial resistance (AMR), Bacteriophages, One-health, Therapeutics commercialization
Abstract

The alarming rise in antimicrobial resistance (AMR) among the drug-resistant pathogens has been attributed to the ESKAPEE group (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumanii, Pseudomonas aeruginosa, Enterobacter sp., and Escherichia coli). Recently, these AMR microbes have become difficult to treat, as they have rendered the existing therapeutics ineffective. Thus, there is an urgent need for effective alternatives to lessen or eliminate the current infections and limit the spread of emerging diseases under the ``One Health'' framework. Bacteriophages (phages) are naturally occurring biological resources with extraordinary potential for biomedical, agriculture/food safety, environmental protection, and energy production. Specific unique properties of phages, such as their bactericidal activity, host specificity, potency, and biocompatibility, make them desirable candidates in therapeutics. The recent biotechnological advancement has broadened the repertoire of phage applications in nanoscience, material science, physical chemistry, and soft

DOI10.1016/j.scitotenv.2023.168461
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

9.8

Divison category: 
Biochemical Sciences
Database: 
Web of Science (WoS)

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