Asymmetric total synthesis of eicosanoid
| Title | Asymmetric total synthesis of eicosanoid |
| Publication Type | Journal Article |
| Year of Publication | 2005 |
| Authors | Mohapatra, DK, Yellol, GS |
| Journal | Arkivoc |
| Issue | Part 3 |
| Pagination | 144-155 |
| Date Published | JAN |
| Type of Article | Article |
| Keywords | cyclopropanation, eicosanoid, lipoxygenase inhibitors, Ring-closing metathesis, Stereoselective |
| Abstract | An asymmetric total synthesis of eicosanoid 4 starting from 2,2- dimethyl-( R)- 1,3- dioxolane-4- carbaldehyde is described. The key steps involved for the synthesis include modified Simmons-Smith cyclopropanation, stereoselective reduction, ring-closing metathesis (RCM) and Nozaki- Hiyama- Kishi coupling reaction. |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 1.177 |
Divison category:
Organic Chemistry