Asymmetric total synthesis of (2S,3S)-3-hydroxypipecolic acid
| Title | Asymmetric total synthesis of (2S,3S)-3-hydroxypipecolic acid |
| Publication Type | Journal Article |
| Year of Publication | 2011 |
| Authors | Chavan, SP, Dumare, NB, Harale, KR, Kalkote, UR |
| Journal | Tetrahedron Letters |
| Volume | 52 |
| Issue | 3 |
| Pagination | 404-406 |
| Date Published | JAN |
| ISSN | 0040-4039 |
| Abstract | A synthetic route to (2S,3S)-3-hydroxypipecolic acid was achieved from readily available nonchiral pool starting material cis-2-butene-1,4-diol and involved Claisen orthoester rearrangement, Sharpless asymmetric dihydroxylation and intramolecular lactamisation of azido lactone as the key steps. (C) 2010 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tetlet.2010.11.062 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.683 |
Divison category:
Organic Chemistry