Article chitinase inhibition induces transcriptional dysregulation altering ecdysteroid-mediated control of spodoptera frugiperda development

TitleArticle chitinase inhibition induces transcriptional dysregulation altering ecdysteroid-mediated control of spodoptera frugiperda development
Publication TypeJournal Article
Year of Publication2024
AuthorsBarbole, RS, Sharma, S, Patil, Y, Giri, AP, Joshi, RS
JournalIscience
Volume27
Issue3
Date PublishedMAR
Type of ArticleArticle
Abstract

Chitinases and ecdysteroid hormones are vital for insect development. Crosstalk between chitin and ecdysteroid metabolism regulation is enigmatic. Here, we examined chitinase inhibition effect on Spodopsilencing and overexpression resulted in ecdysone receptor deregulation. Transcription factors, like Neverland, and other ecdysteroid biosynthesis genes might lead to their upregulation in berberine-fed chitinase activity's impact on ecdysone biosynthesis and its transcriptional crosstalk.

DOI10.1016/j.isci.2024.109280
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

5.8

Divison category: 
Biochemical Sciences
Database: 
Web of Science (WoS)

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