Antimycobacterial agent, (E)-phytol and lauric amide from the plant Lagascea mollis

TitleAntimycobacterial agent, (E)-phytol and lauric amide from the plant Lagascea mollis
Publication TypeJournal Article
Year of Publication2013
AuthorsBhattacharya, AK, Rana, KC
JournalIndian Journal of Chemistry Section B-Organic Chemistry Including Medicinal Chemistry
Volume52
Issue7
Pagination901-903
Date PublishedJUL
ISSN0376-4699
Keywordsamide, chemical transformation, diterpene, Lagascea mollis, structure elucidation
Abstract

Chemical examination of aerial parts of the plant, Lagascea mollis has resulted in the isolation of two compounds, an acyclic diterpene alcohol which has been identified as (E)-phytol 1 and lauric amide 3. Their structures have been elucidated by spectral data and chemical transformations. This is the first report of isolation of both these compounds from this plant It is noteworthy that compound 1 has been found to be a potent antimycobacterial agent and thus, L. mollis could be exploited as an alternative source.

Type of Journal (Indian or Foreign)Indian
Impact Factor (IF)0.489
Divison category: 
Organic Chemistry