Alternate synthesis of enantiomerically pure levetiracetam (Keppra (R))

TitleAlternate synthesis of enantiomerically pure levetiracetam (Keppra (R))
Publication TypeJournal Article
Year of Publication2012
AuthorsMujahid, M, Mujumdar, P, Sasikumar, M, Kunte, SS, Muthukrishnan, M
JournalTetrahedron-Asymmetry
Volume23
Issue20-21
Pagination1512-1515
Date PublishedNOV
ISSN0957-4166
Abstract

A simple and efficient synthesis of levetiracetam has been achieved with high enantiopurity (>99%) starting from commercially available benzyl glycidyl ether. The method is amenable for industrial scale-up. (C) 2012 Elsevier Ltd. All rights reserved.

DOI10.1016/j.tetasy.2012.10.006
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.115
Divison category: 
Organic Chemistry