Alternate synthesis of appetite suppressant (R)-2-benzylmorpholine employing Sharpless asymmetric epoxidation strategy
| Title | Alternate synthesis of appetite suppressant (R)-2-benzylmorpholine employing Sharpless asymmetric epoxidation strategy |
| Publication Type | Journal Article |
| Year of Publication | 2016 |
| Authors | Viswanadh, N, Mujumdar, P, Sasikumar, M, Kunte, SS, Muthukrishnan, M |
| Journal | Tetrahedron Letters |
| Volume | 57 |
| Issue | 8 |
| Pagination | 861-863 |
| Date Published | FEB |
| ISSN | 0040-4039 |
| Keywords | (R)-2-Benzylmorpholine, Appetite suppressant, Sharpless asymmetric epoxidation |
| Abstract | An alternate synthesis of (R)-2-benzylmorpholine 1, an appetite suppressant agent has been accomplished starting from readily available trans-cinnamyl alcohol employing Sharpless asymmetric epoxidation strategy as a key step, with an overall yield of 24%. (C) 2016 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tetlet.2016.01.032 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.347 |
Divison category:
Organic Chemistry