AgOTf-catalyzed dehydrative [3+2] annulation of aziridines with 2-naphthols
| Title | AgOTf-catalyzed dehydrative [3+2] annulation of aziridines with 2-naphthols |
| Publication Type | Journal Article |
| Year of Publication | 2017 |
| Authors | Kaicharla, T, Jacob, A, Gonnade, RG, Biju, AT |
| Journal | Chemical Communications |
| Volume | 53 |
| Issue | 58 |
| Pagination | 8219-8222 |
| Date Published | JUL |
| Abstract | The reaction of 2-naphthols with aziridines in the presence of AgOTf resulting in a dehydrative, formal [3+2] annulation is reported. The reaction allows the synthesis of functionalized benzoindolines, and tolerates a broad range of functional groups. A preliminary study on themechanism of this reaction indicates an SN1-type ring-opening of aziridines. This method is demonstrated for the one-pot synthesis of benzoindoles. |
| DOI | 10.1039/c7cc03425c |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 6.567 |
Divison category:
Center for Material Characterization (CMC)
Organic Chemistry