Acid mediated sulfonylation of para-quinone methides with tosylmethyl isocyanides for the synthesis of diarylmethyl sulfones
| Title | Acid mediated sulfonylation of para-quinone methides with tosylmethyl isocyanides for the synthesis of diarylmethyl sulfones |
| Publication Type | Journal Article |
| Year of Publication | 2021 |
| Authors | Kumar, P, Kale, SB, Gonnade, RG, Das, U |
| Journal | ChemistrySelect |
| Volume | 6 |
| Issue | 28 |
| Pagination | 7158-7161 |
| Date Published | JUL |
| Type of Article | Article |
| ISSN | 2365-6549 |
| Keywords | 1, 6-Conjugate addition, aromatization, Diarylmethylsulfone, para-Quinonemethide, TosMIC |
| Abstract | An efficient, hydrochloric acid promoted reaction for the synthesis of diarylmethyl sulfones has been developed via unprecedented 1, 6-conjugate addition reaction of tosylmethyl isocyanide (TosMIC) with para-quinone methides.This catalyst free reaction provides various diarylmethyl sulfones in good to excellent yields in an operationally simple method under metal free conditions. Further transformations of the productsare also demonstrated. |
| DOI | 10.1002/slct.202102272 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.109 |
Divison category:
Center for Material Characterization (CMC)
Organic Chemistry