(-)-6 alpha-Hydroxy polyanthellin A - a novel antifouling diterpenoid from the Indian soft coral Cladiella krempfi (Hickson)
| Title | (-)-6 alpha-Hydroxy polyanthellin A - a novel antifouling diterpenoid from the Indian soft coral Cladiella krempfi (Hickson) |
| Publication Type | Journal Article |
| Year of Publication | 2011 |
| Authors | Mol, VPLimna, Raveendran, TV, Parameswaran, PS, Kunnath, RJ, Rajamohanan, PR |
| Journal | Canadian Journal of Chemistry-Revue Canadienne De Chimie |
| Volume | 89 |
| Issue | 1 |
| Pagination | 57-60 |
| Date Published | JAN |
| ISSN | 0008-4042 |
| Keywords | antifouling, Balanus amphitrite, biofouling, Cladiella krempfi, diterpenes |
| Abstract | Bioassay-guided purification of methanol extract of the soft coral Cladiella krempfi (Octocorallia: Alcynocea) yielded a novel eunicellin-type diterpenoid, (-)-6 alpha-hydroxy polyanthellin A (1), active against the cyprids of the fouling barnacle, Balanus amphitrite (EC(50) 9.02 mu g/mL; LC(50) 36 mu g/mL; and therapeutic ratio = 4). The structure of compound 1 was determined from its spectral data, including IR, NMR (1D and 2D NMR), and mass spectra. |
| DOI | 10.1139/V10-159 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 0.89 |
Divison category:
Central NMR Facility