1,6-Conjugate-addition-induced [2+1] annulation of para-quinone methides and pyrazolones: synthesis of bis-spiro compounds with contiguous quaternary spiro-centers
| Title | 1,6-Conjugate-addition-induced [2+1] annulation of para-quinone methides and pyrazolones: synthesis of bis-spiro compounds with contiguous quaternary spiro-centers |
| Publication Type | Journal Article |
| Year of Publication | 2019 |
| Authors | Kale, SB, Jori, PK, Thatikonda, T, Gonnade, RG, Das, U |
| Journal | Organic Letters |
| Volume | 21 |
| Issue | 19 |
| Pagination | 7736-7740 |
| Date Published | OCT |
| Type of Article | Article |
| ISSN | 1523-7060 |
| Abstract | A diastereoselective formal 1,6-conjugate-addition-mediated [2 + 1] annulation reaction using p-quinone methides and pyrazolones has been described. The corresponding bis-spiro[cyclohexadienone-cyclopropane-pyrazolone] compounds were obtained in very good yield under mild reaction conditions. |
| DOI | 10.1021/acs.orglett.9b02641 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 6.555 |
Divison category:
Center for Material Characterization (CMC)
Organic Chemistry