Total synthesis of lucidimines/ganocalicines A/B, sinensine E, and ganocochlearine E
| Title | Total synthesis of lucidimines/ganocalicines A/B, sinensine E, and ganocochlearine E |
| Publication Type | Journal Article |
| Year of Publication | 2026 |
| Authors | Sai, GKiran Venk, Ramana, CV |
| Journal | Organic Letters |
| Volume | 28 |
| Issue | 4 |
| Pagination | 1241-1246 |
| Date Published | JAN |
| Type of Article | Article |
| ISSN | 1523-7060 |
| Abstract | The central tetracyclic framework shared by the Ganoderma alkaloids-lucidimines/ganocaclicines A and B, sinensine E, and ganocochlearine E-appears inherently predisposed to arise from a diyne-nitrile cyclotrimerization event. A Co(I)-catalyzed intramolecular [2 + 2 + 2]-alkynenitrile cyclotrimerization has been employed to accomplish the first racemic and enantioselective total syntheses of sinensine E, lucidimine A, and ganocochlearine E, thereby establishing/revising their assigned stereochemical structures. |
| DOI | 10.1021/acs.orglett.5c04999 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 4.6 |
Divison category:
Organic Chemistry
Database:
Web of Science (WoS)
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