<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Patil, Nivedita T.</style></author><author><style face="normal" font="default" size="100%">Patil, Madhuri T.</style></author><author><style face="normal" font="default" size="100%">Gonnade, Rajesh G.</style></author><author><style face="normal" font="default" size="100%">Shashidhar, Mysore S.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Desymmetrization of myo-inositol</style></title><secondary-title><style face="normal" font="default" size="100%">Carbohydrate Research</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Conglomerate</style></keyword><keyword><style  face="normal" font="default" size="100%">Crystallization</style></keyword><keyword><style  face="normal" font="default" size="100%">Cyclitol</style></keyword><keyword><style  face="normal" font="default" size="100%">Enantiomers</style></keyword><keyword><style  face="normal" font="default" size="100%">Inositol</style></keyword><keyword><style  face="normal" font="default" size="100%">Lipid</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">JUL</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">553</style></volume><pages><style face="normal" font="default" size="100%">109505</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;
	Chemistry and biology of phosphoinositols have been intensely investigated areas of research over the last 4-5 decades due to their involvement in cellular signal transduction pathways. Efficient laboratory synthesis of enantiomeric derivatives of inositols was a central issue since they were required for the delineation of the myo-inositol cycle as well as for the total synthesis of polyol based natural products and their derivatives. This essentially meant the development of competent methods for the desymmetrization of myo-inositol leading to the preparation of enantiomeric O-substituted derivatives of myo-inositol. This was approached by: the classical resolution methods involving separable diastereomers, the chiral pool synthesis, enzyme catalysis, asymmetric catalysis and preferential crystallization of enantiomers in a racemic conglomerate. This review summarizes results obtained in author's laboratory, as well as those reported in the literature on attempts at desymmetrization of myo-inositol.&lt;/p&gt;
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	Foreign&lt;/p&gt;
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	2.5&lt;/p&gt;
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