<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ahmed, Neesar</style></author><author><style face="normal" font="default" size="100%">Dasari, Sreekanth</style></author><author><style face="normal" font="default" size="100%">Srivastava, Saumya S.</style></author><author><style face="normal" font="default" size="100%">Sneh, Amita</style></author><author><style face="normal" font="default" size="100%">Ahmad, Absar</style></author><author><style face="normal" font="default" size="100%">Khan, Mohammad Islam</style></author><author><style face="normal" font="default" size="100%">Krishnasastry, M. V.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Taxol and 10-deacetylbaccatinIII induce distinct changes in the dynamics of caveolae</style></title><secondary-title><style face="normal" font="default" size="100%">FEBS Letters</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">10-DeacetylbaccatinIII</style></keyword><keyword><style  face="normal" font="default" size="100%">BaccatinIII</style></keyword><keyword><style  face="normal" font="default" size="100%">Caveolae</style></keyword><keyword><style  face="normal" font="default" size="100%">Cytotoxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Kiss and run dynamic</style></keyword><keyword><style  face="normal" font="default" size="100%">Taxol</style></keyword><keyword><style  face="normal" font="default" size="100%">TIRFM</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2008</style></year><pub-dates><date><style  face="normal" font="default" size="100%">OCT</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">25-26</style></number><publisher><style face="normal" font="default" size="100%">ELSEVIER SCIENCE BV</style></publisher><pub-location><style face="normal" font="default" size="100%">PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS</style></pub-location><volume><style face="normal" font="default" size="100%">582</style></volume><pages><style face="normal" font="default" size="100%">3595-3600</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Taxol treatment of HeLa cells resulted in a transient recruitment of Caveolin-1 to the cell surface followed by internalization. Interestingly, 20 min after 10-deacetylbaccatinIII (10-DAB) treatment, the caveolae displayed faster `kiss and run' dynamics while BaccatinIII (BacIII) did not induce any change. Sustained phosphorylation of Caveolin-1 is observed upon treatment and between Taxol and 10-DAB, the former shows phosphorylated Raf-1, ERK1/2 and hyperphosphorylated Bcl-2 while the later showed much less magnitude of the same. BacIII treatment did not induce phosphorylation of Raf-1 or Bcl-2. It is possible that Taxol might act on multiple targets and the side chain may be crucial. (c) 2008 Federation of European Biochemical Societies. Published by Elsevier B. V. All rights reserved.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">25-26</style></issue><work-type><style face="normal" font="default" size="100%">Article</style></work-type><custom3><style face="normal" font="default" size="100%">Foreign</style></custom3><custom4><style face="normal" font="default" size="100%">3.519</style></custom4></record></records></xml>