<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Katade, S. R.</style></author><author><style face="normal" font="default" size="100%">Misar, Ashwini V.</style></author><author><style face="normal" font="default" size="100%">Mujumdar, Arvind M.</style></author><author><style face="normal" font="default" size="100%">Phalgune, U. D.</style></author><author><style face="normal" font="default" size="100%">Wakharkar, R. D.</style></author><author><style face="normal" font="default" size="100%">Deshpande, N. R.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">CNS Depressant activity of ethanol extract of sterculia guttata seeds in mice</style></title><secondary-title><style face="normal" font="default" size="100%">Indian Journal of Pharmaceutical Sciences</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Barbitone sodium</style></keyword><keyword><style  face="normal" font="default" size="100%">CNS depressant activity</style></keyword><keyword><style  face="normal" font="default" size="100%">pentobarbitone sodium</style></keyword><keyword><style  face="normal" font="default" size="100%">Sterculia guttata Roxb.</style></keyword><keyword><style  face="normal" font="default" size="100%">Swiss albino mice</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2009</style></year><pub-dates><date><style  face="normal" font="default" size="100%">JUL</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">4</style></number><publisher><style face="normal" font="default" size="100%">MEDKNOW PUBLICATIONS</style></publisher><pub-location><style face="normal" font="default" size="100%">A-108-109 KANARA BUSINESS CENTRE, GHAKTOPAR, MUMBAI, 400075, INDIA</style></pub-location><volume><style face="normal" font="default" size="100%">71</style></volume><pages><style face="normal" font="default" size="100%">445-U167</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Shade dried, powdered seeds of Sterculia guttata were extracted using a Soxhlet extractor with ethanol. Ethanol was removed under reduced pressure and dried to obtained crude extract. This extract was evaluated for its effect on behavioral changes, exploratory activity and barbiturate-sleeping time, using appropriate standard methods in mice. The extract exhibited dose-dependent CNS depressant activity.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><custom3><style face="normal" font="default" size="100%">Indian </style></custom3><custom4><style face="normal" font="default" size="100%">0.455</style></custom4></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ruikar, Anjali D.</style></author><author><style face="normal" font="default" size="100%">Misar, Ashwini V.</style></author><author><style face="normal" font="default" size="100%">Jadhav, Ravindra B.</style></author><author><style face="normal" font="default" size="100%">Rojatkar, Supada R.</style></author><author><style face="normal" font="default" size="100%">Mujumdar, Arvind M.</style></author><author><style face="normal" font="default" size="100%">Puranik, Vedavati G.</style></author><author><style face="normal" font="default" size="100%">Deshpande, Nirmala R.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Sesquiterpene lactone, a potent drug molecule from artemisia pallens wall with anti-inflammatory activity</style></title><secondary-title><style face="normal" font="default" size="100%">Arzneimittel-Forschung-Drug Research</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-inflammatory activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Artemisia pollens</style></keyword><keyword><style  face="normal" font="default" size="100%">Asteraceae</style></keyword><keyword><style  face="normal" font="default" size="100%">Mice</style></keyword><keyword><style  face="normal" font="default" size="100%">Single crystal x-ray structure</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2011</style></year><pub-dates><date><style  face="normal" font="default" size="100%">DEC</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">9</style></number><publisher><style face="normal" font="default" size="100%">ECV-EDITIO CANTOR VERLAG MEDIZIN NATURWISSENSCHAFTEN</style></publisher><pub-location><style face="normal" font="default" size="100%">BANDELSTOCKWEG 20, POSTFACH 1255, D-88322 AULENDORF, GERMANY</style></pub-location><volume><style face="normal" font="default" size="100%">61</style></volume><pages><style face="normal" font="default" size="100%">510-514</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;The present study was carried out to investigate the anti-inflammatory activities of bioactive secondary metabolites of Artemisia pallens Wall, an aromatic herb from family Asteraceae. The results provide evidence for the topical anti-inflammatory properties of Artemisia pallens Wall. The compounds were isolated from the acetone extract of the plant material. The isolates were tested on Swiss albino mice using 12-O-tetradecanoyl phorbol-13-acetate (TPA) induced ear edema. One of the molecules from the extract indicated potent anti-inflammatory activity equivalent to indometacin (CAS 53-86-1). Elucidation of the molecular structures by single crystal x-ray diffraction studies revealed the conformational differences that the six membered rings in both the molecules are at an angle of 28.79 degrees. Presence of hydroxy function for compound 2 may be responsible for higher potency.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">9</style></issue><custom3><style face="normal" font="default" size="100%">Foreign</style></custom3><custom4><style face="normal" font="default" size="100%">0.722
</style></custom4></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Puranik, Ninad V.</style></author><author><style face="normal" font="default" size="100%">Swami, Sagar</style></author><author><style face="normal" font="default" size="100%">Misar, Ashwini V.</style></author><author><style face="normal" font="default" size="100%">Mamgain, Ritu</style></author><author><style face="normal" font="default" size="100%">Gulawani, Swapnaja S.</style></author><author><style face="normal" font="default" size="100%">Dhiman, Sarkar</style></author><author><style face="normal" font="default" size="100%">Srivastava, Pratibha</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">First synthesis of podocarflavone A and its analogs and evaluation of their antimycobacterial potential against mycobacterium tuberculosis with the support of virtual screening</style></title><secondary-title><style face="normal" font="default" size="100%">Natural Product Research</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">and MMGBSA</style></keyword><keyword><style  face="normal" font="default" size="100%">antimycobacterial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">docking</style></keyword><keyword><style  face="normal" font="default" size="100%">MD simulations</style></keyword><keyword><style  face="normal" font="default" size="100%">MMPBSA</style></keyword><keyword><style  face="normal" font="default" size="100%">Podocarflavone A synthesis</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">AUG</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">36</style></volume><pages><style face="normal" font="default" size="100%">3879-3886</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;
	The first synthetic route developed for Podocarflavone A reported from Podocarpus macrophyllus and its analogs in 7 steps. Computational analysis for binding with the pantothenate kinase (3AVO) of Mycobacterium tuberculosis showed their docking score (ds) in the range of -8.9 to -9.3 Kcal/mol. MD simulations delineated the stability of the protein-ligand complexes in the TIP3P model. MMGBSA and MMPBSA values of 8d were -42.46 Kcal/mol and -14.58 Kcal/mol, respectively. Further in-vitro antitubercular screening of compounds 8a, 8d, and 8e against M. tuberculosis H37Ra using XRMA protocol exhibited promising antimycobacterial activity with IC50 values 21.82 mu g/mL, 15.55 mu g/mL, and 16.56 mu g/mL, respectively. Compounds 8a, 8d, and 8e showed antibacterial activity with IC50 values 41.56 mu g/mL, 24.72 mu g/mL, and 72.45 mu g/mL respectively against the Staphylococcus aureus. 8a and 8d showed inhibition with IC50 values 39.6 mu g/mL and 27.64 mu g/mL, respectively, against Bacillus subtilis. The present study could help in the further development of lead molecules against tuberculosis.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">15</style></issue><work-type><style face="normal" font="default" size="100%">Article</style></work-type><custom3><style face="normal" font="default" size="100%">&lt;p&gt;Foreign&lt;/p&gt;
</style></custom3><custom4><style face="normal" font="default" size="100%">&lt;p&gt;
	2.488&lt;/p&gt;
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