<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sangeetha, Murthy</style></author><author><style face="normal" font="default" size="100%">Sasirekha, Sivakumar</style></author><author><style face="normal" font="default" size="100%">Mahendran, Jaganathan</style></author><author><style face="normal" font="default" size="100%">Sivarajan, Anbalmani</style></author><author><style face="normal" font="default" size="100%">Radhakrishnan, Manikkam</style></author><author><style face="normal" font="default" size="100%">Manigundan, Kaari</style></author><author><style face="normal" font="default" size="100%">Dastager, Syed G.</style></author><author><style face="normal" font="default" size="100%">Sengottuvelu, Singaravel</style></author><author><style face="normal" font="default" size="100%">Balagurunathan, Ramasamy</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Multifunctional metabolites of Streptomyces kunmingensis BS19 from bamboo rhizosphere soil</style></title><secondary-title><style face="normal" font="default" size="100%">International Microbiology</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">NOV</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;
	&lt;span style=&quot;font-family: Merriweather, serif; font-size: 18px;&quot;&gt;A pigmented bioactive molecule from&amp;nbsp;&lt;/span&gt;&lt;i style=&quot;box-sizing: inherit; font-family: Merriweather, serif; font-size: 18px;&quot;&gt;Streptomyces kunmingensis&lt;/i&gt;&lt;span style=&quot;font-family: Merriweather, serif; font-size: 18px;&quot;&gt;&amp;nbsp;BS19 was isolated, characterized, and evaluated for anti-infective, antiproliferative, and wound-healing properties. The yellow–red pigment produced from the strain BS19 showed promising activity against methicillin-resistant&amp;nbsp;&lt;/span&gt;&lt;i style=&quot;box-sizing: inherit; font-family: Merriweather, serif; font-size: 18px;&quot;&gt;Staphylococcus aureus&lt;/i&gt;&lt;span style=&quot;font-family: Merriweather, serif; font-size: 18px;&quot;&gt;&amp;nbsp;(MRSA) and&amp;nbsp;&lt;/span&gt;&lt;i style=&quot;box-sizing: inherit; font-family: Merriweather, serif; font-size: 18px;&quot;&gt;Mycobacterium tuberculosis&lt;/i&gt;&lt;span style=&quot;font-family: Merriweather, serif; font-size: 18px;&quot;&gt;. Extracellular bioactive pigment from the strain BS19 was produced by agar surface fermentation and purified through bioassay guided preparative HPLC-based purification. Based on the results of UV, FT-IR, GC–MS,&amp;nbsp;&lt;/span&gt;&lt;sup style=&quot;box-sizing: inherit; font-family: Merriweather, serif;&quot;&gt;1&lt;/sup&gt;&lt;span style=&quot;font-family: Merriweather, serif; font-size: 18px;&quot;&gt;H NMR, and&amp;nbsp;&lt;/span&gt;&lt;sup style=&quot;box-sizing: inherit; font-family: Merriweather, serif;&quot;&gt;13&lt;/sup&gt;&lt;span style=&quot;font-family: Merriweather, serif; font-size: 18px;&quot;&gt;C NMR spectral analyses, the purified pigment was identified as a chromopeptide class of molecule with phenoxazinone chromophore. Its molecular weight was determined as the chemical formula C&lt;/span&gt;&lt;span style=&quot;box-sizing: inherit; bottom: -0.25em; font-size: 13.5px; line-height: 0; position: relative; vertical-align: baseline; font-family: Merriweather, serif;&quot;&gt;64&lt;/span&gt;&lt;span style=&quot;font-family: Merriweather, serif; font-size: 18px;&quot;&gt;H&lt;/span&gt;&lt;span style=&quot;box-sizing: inherit; bottom: -0.25em; font-size: 13.5px; line-height: 0; position: relative; vertical-align: baseline; font-family: Merriweather, serif;&quot;&gt;90&lt;/span&gt;&lt;span style=&quot;font-family: Merriweather, serif; font-size: 18px;&quot;&gt;N&lt;/span&gt;&lt;span style=&quot;box-sizing: inherit; bottom: -0.25em; font-size: 13.5px; line-height: 0; position: relative; vertical-align: baseline; font-family: Merriweather, serif;&quot;&gt;12&lt;/span&gt;&lt;span style=&quot;font-family: Merriweather, serif; font-size: 18px;&quot;&gt;O&lt;/span&gt;&lt;span style=&quot;box-sizing: inherit; bottom: -0.25em; font-size: 13.5px; line-height: 0; position: relative; vertical-align: baseline; font-family: Merriweather, serif;&quot;&gt;16&lt;/span&gt;&lt;span style=&quot;font-family: Merriweather, serif; font-size: 18px;&quot;&gt;&amp;nbsp;and molecular weight 1283&amp;nbsp;g/mol. It exhibited promising antimicrobial activity against&amp;nbsp;&lt;/span&gt;&lt;i style=&quot;box-sizing: inherit; font-family: Merriweather, serif; font-size: 18px;&quot;&gt;Staphylococcus aureus&lt;/i&gt;&lt;span style=&quot;font-family: Merriweather, serif; font-size: 18px;&quot;&gt;&amp;nbsp;(ATCC 1720) and antiproliferative activity against 14 types of human cancer cell lines. It showed good in vivo wound-healing activity in the rat model. The present study explored&amp;nbsp;&lt;/span&gt;&lt;i style=&quot;box-sizing: inherit; font-family: Merriweather, serif; font-size: 18px;&quot;&gt;Streptomyces kunmingensis&lt;/i&gt;&lt;span style=&quot;font-family: Merriweather, serif; font-size: 18px;&quot;&gt;&amp;nbsp;as a newly added source for the isolation of chromopeptide antibiotics for antimicrobial, wound-healing, and anticancer applications.&lt;/span&gt;&lt;/p&gt;
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	Foreign&lt;/p&gt;
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	3.1&lt;/p&gt;
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