<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Pramod C.</style></author><author><style face="normal" font="default" size="100%">Pawar, Jayant</style></author><author><style face="normal" font="default" size="100%">Mane, Deepali P.</style></author><author><style face="normal" font="default" size="100%">Khadase, Ashok N.</style></author><author><style face="normal" font="default" size="100%">Chaudhari, Aditya R.</style></author><author><style face="normal" font="default" size="100%">Ughade, Supriya P.</style></author><author><style face="normal" font="default" size="100%">Chaudhari, Ravindra D.</style></author><author><style face="normal" font="default" size="100%">Agawane, Sachin B.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Green synthesis of silver and gold ultra nanocomposites from silk fibroin and their application for treatment of endodontic infections</style></title><secondary-title><style face="normal" font="default" size="100%">Emergent Materials</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">JUN</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">2645–2660</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;
	&lt;span style=&quot;font-family: Merriweather, serif; font-size: 18px;&quot;&gt;The present study is designed to investigate the antibacterial efficacy of&amp;nbsp;&lt;/span&gt;&lt;i style=&quot;box-sizing: inherit; font-family: Merriweather, serif; font-size: 18px;&quot;&gt;B. mori&lt;/i&gt;&lt;span style=&quot;font-family: Merriweather, serif; font-size: 18px;&quot;&gt;&amp;nbsp;silk fibroin based silver and gold ultra bio-nanocomposites (SF-AgUNC and SF-AuUNC) against&amp;nbsp;&lt;/span&gt;&lt;i style=&quot;box-sizing: inherit; font-family: Merriweather, serif; font-size: 18px;&quot;&gt;Enterococcus faecalis&lt;/i&gt;&lt;span style=&quot;font-family: Merriweather, serif; font-size: 18px;&quot;&gt;&amp;nbsp;for endodontic disinfection. The SF-AgUNC and SF-AuUNC based irrigant solution was tested&amp;nbsp;&lt;/span&gt;&lt;i style=&quot;box-sizing: inherit; font-family: Merriweather, serif; font-size: 18px;&quot;&gt;in- vitro&lt;/i&gt;&lt;span style=&quot;font-family: Merriweather, serif; font-size: 18px;&quot;&gt;&amp;nbsp;against&amp;nbsp;&lt;/span&gt;&lt;i style=&quot;box-sizing: inherit; font-family: Merriweather, serif; font-size: 18px;&quot;&gt;Enterococcus faecalis&lt;/i&gt;&lt;span style=&quot;font-family: Merriweather, serif; font-size: 18px;&quot;&gt;&amp;nbsp;(ATCC: 29212). In this direction, SF-AgUNC and SF-AuUNC synthesized by silk fibroin are very important as they are economically cheap and easy to biosynthesize. The synthesis of SF-AgUNC and SF-AuUNC was accomplished by dissolving 1 mM silver nitrate and 0.5 mM auric chloride respectively in 10 ml of fibroin as precursors. The structural and morphological analysis was executed by UV-Vis Spectroscopy, X-ray diffraction (XRD), Fourier transform infrared spectroscopic analysis (FTIR), Field Emission Scanning Electron Microscopy (FESEM), Transmission electron microscopy (TEM), Energy-dispersive X-ray spectroscopy (EDAX) and X-ray photoelectron spectroscopy (XPS). The qualitative antimicrobial activity of SF-AgUNC and SF-AuUNC were performed against inoculum of&amp;nbsp;&lt;/span&gt;&lt;i style=&quot;box-sizing: inherit; font-family: Merriweather, serif; font-size: 18px;&quot;&gt;Enterococcus faecalis&lt;/i&gt;&lt;span style=&quot;font-family: Merriweather, serif; font-size: 18px;&quot;&gt;&amp;nbsp;containing 1⨯10&lt;/span&gt;&lt;sup style=&quot;box-sizing: inherit; font-family: Merriweather, serif;&quot;&gt;5&lt;/sup&gt;&lt;span style=&quot;font-family: Merriweather, serif; font-size: 18px;&quot;&gt;&amp;nbsp;CFU/ ml. The same solutions were tested on dentine specimens inoculated with bacterial cultures and found remarkable biofilm reduction. The structural and morphological analysis reveals the formation of SF-AgUNC and SF-AuUNC having quasi-spherical morphology. The average particle size for SF-AgUNC and SF-AuUNC was same (~ 8 nm). The XRD study confirms that, both SF-AgUNC and SF-AuUNC were crystalline in nature. The bacterial growth inhibition and significant biofilm reduction was observed on dentine specimens treated with SF-AgUNC, SF-AuUNC and positive control. In antibacterial study, at 30 μg/well concentration of SF-AgUNC and SF-AuUNC, 3.13 ± 0.22 and 1.13 ± 0.22 cm of zone of inhibition was noted respectively. Moreover, growth of&amp;nbsp;&lt;/span&gt;&lt;i style=&quot;box-sizing: inherit; font-family: Merriweather, serif; font-size: 18px;&quot;&gt;Enterococcus faecalis&lt;/i&gt;&lt;span style=&quot;font-family: Merriweather, serif; font-size: 18px;&quot;&gt;&amp;nbsp;was completely inhibited at 20 μg/ml and 30 μg/ml when treated with SF-AgUNC and SF-AuUNC respectively. Hence, the present study concludes that SF-AgUNC and SF-AuUNC can be used as an effective intracanal medicament for the treatment of dental problems with no cyto toxicity.&lt;/span&gt;&lt;/p&gt;
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