<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sudrik, Vilas</style></author><author><style face="normal" font="default" size="100%">Karpe, Dnyaneshwar</style></author><author><style face="normal" font="default" size="100%">Jadhav, Vrushali</style></author><author><style face="normal" font="default" size="100%">Lawande, Shamrao</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Efficient one-pot process for synthesis of antiviral drug Ganciclovir</style></title><secondary-title><style face="normal" font="default" size="100%">Journal of Chemical Sciences</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Acidic Amberlite IR-120</style></keyword><keyword><style  face="normal" font="default" size="100%">acyclic nucleoside</style></keyword><keyword><style  face="normal" font="default" size="100%">anti-herpes</style></keyword><keyword><style  face="normal" font="default" size="100%">commercially viable</style></keyword><keyword><style  face="normal" font="default" size="100%">iodine</style></keyword><keyword><style  face="normal" font="default" size="100%">one-pot process</style></keyword><keyword><style  face="normal" font="default" size="100%">regiospecific</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">SEP </style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">136</style></volume><pages><style face="normal" font="default" size="100%">71</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;
	A regioselective novel one-pot synthesis of heterocyclic purine derivative antiviral agent Ganciclovir in which initially guanine is treated with acetic anhydride in the presence of iodine (5%) to get diacetyl guanine intermediate, which undergoes in situ N-alkylation with AMDP in presence of catalytic acidic Amberlite IR-120 to get N-alkylated intermediate and finally deacetylation to get pure regioselective Ganciclovir, which is commercially viable and eco-friendly.Graphical abstractWe developed one-pot synthesis of antiviral drug Ganciclovir. Initially, Guanine is treated with acetic anhydride and iodine to yield diacetyl guanine 3. This intermediate then reacted with AMDP in the presence of acidic Amberlite IR-120 to obtain compound 5. Finally, deacetylation yields Ganciclovir 1, a commercially viable and eco-friendly process.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Article</style></work-type><custom3><style face="normal" font="default" size="100%">&lt;p&gt;
	Indian&lt;/p&gt;
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	1.7&lt;/p&gt;
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