<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Handore, K. L.</style></author><author><style face="normal" font="default" size="100%">Kalmode, H. P.</style></author><author><style face="normal" font="default" size="100%">Sayyad, S.</style></author><author><style face="normal" font="default" size="100%">Seetharamsingh, B.</style></author><author><style face="normal" font="default" size="100%">Gathalkar, G.</style></author><author><style face="normal" font="default" size="100%">Padole, S.</style></author><author><style face="normal" font="default" size="100%">Pawar, P. V.</style></author><author><style face="normal" font="default" size="100%">Joseph, M.</style></author><author><style face="normal" font="default" size="100%">Sen, A.</style></author><author><style face="normal" font="default" size="100%">Reddy, D. S.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Insect-repellent and mosquitocidal effects of noreremophilane- and nardoaristolone-based compounds</style></title><secondary-title><style face="normal" font="default" size="100%">ACS Omega</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">JAN</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">4</style></volume><pages><style face="normal" font="default" size="100%">2188–2195</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Here, we disclose novel mosquito-repellent synthetic hydrindanes based on noreremophilanes and nardoaristolone B which show increased activity against adult females of Aedes aegypti. The noreremophilanes and nardoaristolone B with hydrindane skeleton are structurally related to nootkatone with decalin skeleton, a well-studied natural product extracted from a grape fruit. Out of our library of compounds synthesized based on the noreremophilanes and nardoaristolone B scaffolds, NDS-100598 (compound 20) exhibits higher repellent and knock-down effects at a very low concentration (0.25 mg/cm2), while a few analogues showed considerably enhanced activity compared to racemic nootkatone. This is the first report documenting insect-repellent and knock-down activity of the noreremophilanes class of compounds.&lt;/p&gt;
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