<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Mujahid, Mohammad</style></author><author><style face="normal" font="default" size="100%">Subramanian, Jambu</style></author><author><style face="normal" font="default" size="100%">Nalla, Viswanadh</style></author><author><style face="normal" font="default" size="100%">Sasikumar, Murugesan</style></author><author><style face="normal" font="default" size="100%">Kunte, Sunita Sharad</style></author><author><style face="normal" font="default" size="100%">Muthukrishnan, Murugan</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">New and efficient enantioselective synthesis of both enantiomers of the calcium channel blocker bepridil</style></title><secondary-title><style face="normal" font="default" size="100%">New Journal of Chemistry</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">JAN</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">41</style></volume><pages><style face="normal" font="default" size="100%">824-829</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">A concise and efficient enantioselective synthesis of both enantiomers of bepridil, a calcium channel blocker, is reported. Jacobsen's hydrolytic kinetic resolution method was utilized to resolve racemic 2-(isobutoxymethyl) oxirane. The incorporation of the succinimide moiety by the Mitsunobu reaction, which was investigated in detail, occurred without any loss of enantioselectivity. Using this strategy, both enantiomers of the target molecule were obtained in good yield and with high enantiopurity (ee &gt; 99%).</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><custom3><style face="normal" font="default" size="100%">Foreign</style></custom3><custom4><style face="normal" font="default" size="100%">3.277</style></custom4></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Nalla, Viswanadh</style></author><author><style face="normal" font="default" size="100%">Shaikh, Aslam</style></author><author><style face="normal" font="default" size="100%">Bapat, Sanket</style></author><author><style face="normal" font="default" size="100%">Vyas, Renu</style></author><author><style face="normal" font="default" size="100%">Karthikeyan, M.</style></author><author><style face="normal" font="default" size="100%">Yogeeswari, P.</style></author><author><style face="normal" font="default" size="100%">Sriram, D.</style></author><author><style face="normal" font="default" size="100%">Muthukrishnan, M.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Identification of potent chromone embedded [1,2,3]-triazoles as novel anti-tubercular agents</style></title><secondary-title><style face="normal" font="default" size="100%">Royal Society Open Science</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">APR</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">5</style></volume><pages><style face="normal" font="default" size="100%">Article Number: 171750</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">A series of 20 novel chromone embedded [1,2,3]-triazoles derivatives were synthesized via an easy and convenient synthetic procedure starting from 2-hydroxy acetophenone. The in vitro anti-mycobacterial evaluation studies carried out in this work reveal that seven compounds exhibit significant inhibition against Mycobacterium tuberculosis H37Rv strain with MIC in the range of 1.56-12.5 mu g ml(-1). Noticeably, compound 6s was the most potent compound in vitro with a MIC value of 1.56 mu g ml(-1). Molecular docking and chemoinformatics studies revealed that compound 6s displayed drug-like properties against the enoyl-acyl carrier protein reductase of M. tuberculosis further establishing its potential as a potent inhibitor.</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><custom3><style face="normal" font="default" size="100%">Foreign</style></custom3><custom4><style face="normal" font="default" size="100%">2.243</style></custom4></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ghotekar, Ganesh S.</style></author><author><style face="normal" font="default" size="100%">More, Devidas A.</style></author><author><style face="normal" font="default" size="100%">Nalla, Viswanadh</style></author><author><style face="normal" font="default" size="100%">Muthukrishnan, M.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">New enantioselective synthesis of antiobesity drug lorcaserin</style></title><secondary-title><style face="normal" font="default" size="100%">New Journal of Chemistry</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">NOV </style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">43</style></volume><pages><style face="normal" font="default" size="100%">16876-16880</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;A simple and efficient enantioselective synthesis of anti-obesity drug lorcaerin starting from easily accessible 3-chlorostyrene oxide has been described for the first time employing hydrolytic kinetic resolution as a source of chirality. The protocol might also be useful in the synthesis of structural variants of lorcaserin.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">43</style></issue><work-type><style face="normal" font="default" size="100%">Article</style></work-type><custom3><style face="normal" font="default" size="100%">&lt;p&gt;Foreign&lt;/p&gt;
</style></custom3><custom4><style face="normal" font="default" size="100%">&lt;p&gt;3.069&lt;/p&gt;
</style></custom4></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Nalla, Viswanadh</style></author><author><style face="normal" font="default" size="100%">Mujahid, Mohammad</style></author><author><style face="normal" font="default" size="100%">Sasikumar, Murugesan</style></author><author><style face="normal" font="default" size="100%">Mujumdar, Prashant</style></author><author><style face="normal" font="default" size="100%">Muthukrishnan, Murugan</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Efficient synthesis of optically active herbicide (S)-metolachlor via reductive ring opening of 2-methoxymethylaziridine</style></title><secondary-title><style face="normal" font="default" size="100%">Arkivoc</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Aziridine</style></keyword><keyword><style  face="normal" font="default" size="100%">Epoxide</style></keyword><keyword><style  face="normal" font="default" size="100%">Epoxide ring opening</style></keyword><keyword><style  face="normal" font="default" size="100%">herbicide synthesis</style></keyword><keyword><style  face="normal" font="default" size="100%">Metolachlor</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">JUL</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;An efficient synthesis of a well known chiral herbicide, (S)-metolachlor has been described using 2methoxymethylaziridine ring formation and reductive ring opening as key steps using commercially available (R)-epichlorohydrin. The present protocol delivers the required enantiomer of metolachlor in overall yield of 50.8% and high enantiopurity (&amp;gt;99%).&lt;/p&gt;
</style></abstract><work-type><style face="normal" font="default" size="100%">Article</style></work-type><custom3><style face="normal" font="default" size="100%">&lt;p&gt;Foreign&lt;/p&gt;
</style></custom3><custom4><style face="normal" font="default" size="100%">&lt;p&gt;0.9&lt;/p&gt;
</style></custom4></record></records></xml>