<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Chopade, Anil U.</style></author><author><style face="normal" font="default" size="100%">Chopade, Manojkumar U.</style></author><author><style face="normal" font="default" size="100%">Chanda, Bhanu M.</style></author><author><style face="normal" font="default" size="100%">Sawaikar, Dilip D.</style></author><author><style face="normal" font="default" size="100%">Sonawane, Kiran B.</style></author><author><style face="normal" font="default" size="100%">Gurjar, Mukund K.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Synthesis of (+/-)-thia-calanolide A, its resolution and in vitro biological evaluation</style></title><secondary-title><style face="normal" font="default" size="100%">Arabian Journal of Chemistry</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">NOV</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">S1597-S1602</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">A synthesis of (+/-)-thia-calanolide A 3 has been successfully accomplished starting from 3,5-dimethoxythiophenol 4, in six steps in an overall yield of 4.5%. The key reaction involved Friedel-Crafts tigloylation of 5,7-dihydroxy-4-n-propyl thiocoumarin 6 employing an appropriate solvent of CS2-PhNO2 in a ratio of 7:3. In its biological evaluation for anti-HIV activity, (+/-)-thia-calanolide A 3 demonstrated comparatively less activity with calanolide A and its synthetic analogue aza-calanolide. Further, (+/-)-3 has been resolved by chiral HPLC to (+) and (-)-3. (C) 2012 Production and hosting by Elsevier B.V. on behalf of King Saud University.</style></abstract><custom3><style face="normal" font="default" size="100%">Foreign</style></custom3><custom4><style face="normal" font="default" size="100%">3.613</style></custom4></record></records></xml>