<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Kumbhalkar, Bhagyashri</style></author><author><style face="normal" font="default" size="100%">Walunj, Tanhaji</style></author><author><style face="normal" font="default" size="100%">Chavan, Sandeep</style></author><author><style face="normal" font="default" size="100%">Gupta, Vidya</style></author><author><style face="normal" font="default" size="100%">Deshmukh, Vineeta</style></author><author><style face="normal" font="default" size="100%">Sardeshmukh, Sadanand</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Simultaneous identification and estimation of glycyrrhizin, glabridin, and 18β‐glycyrrhetinic acid in de‐glycyrrhized Ayurvedic lipid‐based formulation of Glycyrrhiza glabra using dual wavelength reverse phase‐high‐performance liquid chromatography </style></title><secondary-title><style face="normal" font="default" size="100%">Separation Science Plus</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">AUG</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">3</style></volume><pages><style face="normal" font="default" size="100%">460-471</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Plant‐based Ayurvedic formulations such as medicated oils, confectioneries, etc. are developed with a rationale of selecting specific compounds for targeted action and minimal side effects. It is imperative to develop an analytical method to simultaneously identify and quantify the targeted compounds for good resolution with low retention time. The present assay using reverse phase‐high‐performance liquid chromatography is optimized to resolve glycyrrhizin, glabridin, and 18β‐glycyrrhetinic acid simultaneously at retention times of 6.6, 8.1, and 10.2&amp;nbsp;min, respectively, using acidified mobile phase from &lt;i&gt;Glycyrrhiza glabra&lt;/i&gt; utilized in Ayurvedic lipid (cow's ghee and sesame oil) based formulations. Raw material, its decoction, and residues formed during preparation steps were extracted in methanol while lipid formulations were extracted using a binary solvent system of methanol and &lt;i&gt;n&lt;/i&gt;‐hexane. The separation was performed on Hypersil gold column maintained at 40°C using 0.2% ortho‐phosphoric acid with pH 3.5 in water and acetonitrile as binary gradient mobile phase. The compounds were detected at wavelengths 230 (glabridin) and 254 (glycyrrhizin and 18β‐glycyrrhetinic acid) nm. The method revealed de‐glycyrrhized finished products containing glabridin and 18β‐glycyrrhetinic acid having medicinal value.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">10</style></issue><custom3><style face="normal" font="default" size="100%">&lt;p&gt;Foreign&lt;/p&gt;
</style></custom3><custom4><style face="normal" font="default" size="100%">&lt;p&gt;2.516&lt;/p&gt;
</style></custom4></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Chavan, Sandeep</style></author><author><style face="normal" font="default" size="100%">Bhuvad, Sushama</style></author><author><style face="normal" font="default" size="100%">Kumbhlakar, Bhagyashri</style></author><author><style face="normal" font="default" size="100%">Auti, Jyoti</style></author><author><style face="normal" font="default" size="100%">Walunj, Tanhaji</style></author><author><style face="normal" font="default" size="100%">Pathak, Shridevi</style></author><author><style face="normal" font="default" size="100%">Tanpure, Rahul</style></author><author><style face="normal" font="default" size="100%">Gujar, Shweta</style></author><author><style face="normal" font="default" size="100%">Shinde, Jagdish</style></author><author><style face="normal" font="default" size="100%">Kulkarni, Arvind</style></author><author><style face="normal" font="default" size="100%">Gupta, Vidya</style></author><author><style face="normal" font="default" size="100%">Deshmukh, Vineeta</style></author><author><style face="normal" font="default" size="100%">Sardeshmukh, Sadanand</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antimicrobial and antioxidant potential of a standardized ayurvedic formulation explains its clinical efficacy as gargles in post-radiotherapy oral cancer patients</style></title><secondary-title><style face="normal" font="default" size="100%">Journal of Herbal Medicine</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-microbial</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Gandush</style></keyword><keyword><style  face="normal" font="default" size="100%">Gargle therapy</style></keyword><keyword><style  face="normal" font="default" size="100%">Oral cavity cancers</style></keyword><keyword><style  face="normal" font="default" size="100%">Radiotherapy side effects</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">DEC</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">30</style></volume><pages><style face="normal" font="default" size="100%">100510</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Introduction: Exploring the antioxidant and antimicrobial potential of a standardized proprietary poly-herbal powder and evaluating its clinical efficacy as an Ayurvedic gargle (Gandush) for reducing oral microbial load and side effects of radiotherapy in oral cavity cancer patients was the aim of this pilot study. Methods: Formulation (Gandush Churna) comprising Terminalia chebula Retz., Terminalia bellirica (Gaertn.) Roxb., Phyllanthus emblica L. and Curcuma longa L. and its decoction (Gandush Kwath) were standardized. In-vitro antioxidant potential and antimicrobial activity against selective bacterial and fungal strains were studied. Oral cavity cancer patients who had undergone radiotherapy were enrolled. The decoction was prepared by soaking Gandush Churna in water, boiling and reducing by 50 %; and was used for gargling, twice a day, for 7 days. Total microbial count and identification of microbiota in the oral cavity as well as symptoms graded as per Common Terminology Criteria for Adverse Events, were noted before and after the treatment. Change in microbial load and shift in symptom gradations were analyzed. Results: A monograph with physicochemical, chromatography, safety and stability parameters was developed. The decoction possessed good in-vitro antioxidant and antimicrobial activities. Gargling therapy significantly reduced bacterial load while mildly controlled the fungal infection in oral cavity cancer patients. It significantly reduced the severity of symptoms viz. stomatitis and local pain, with considerably decreased xerostomia and dysphagia. Conclusions: Intervention of gargle therapy using poly-herbal formulation may serve as an effective complementary treatment to improve oral hygiene and reduce side effects of radiotherapy in oral cancer patients.</style></abstract><work-type><style face="normal" font="default" size="100%">Article</style></work-type><custom3><style face="normal" font="default" size="100%">Foreign</style></custom3><custom4><style face="normal" font="default" size="100%">3.032</style></custom4></record></records></xml>