<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Dixit, Shailesh S.</style></author><author><style face="normal" font="default" size="100%">Kulkarni, Atul</style></author><author><style face="normal" font="default" size="100%">Seo, Hyo Hyun</style></author><author><style face="normal" font="default" size="100%">Gadgil, Jayant</style></author><author><style face="normal" font="default" size="100%">Dingre, Medini</style></author><author><style face="normal" font="default" size="100%">Umar, Ahmad</style></author><author><style face="normal" font="default" size="100%">Moh, Sang Hyun</style></author><author><style face="normal" font="default" size="100%">Parasharami, Varsha A.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Anti-oxidant properties of ficus religiosa L. Bark extract on human keratinocytes</style></title><secondary-title><style face="normal" font="default" size="100%">Science of Advanced Materials</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-Oxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Catalase Assay</style></keyword><keyword><style  face="normal" font="default" size="100%">DPPH Assay</style></keyword><keyword><style  face="normal" font="default" size="100%">Ficus religiosa</style></keyword><keyword><style  face="normal" font="default" size="100%">Keratinocyte HaCaT Cell Line</style></keyword><keyword><style  face="normal" font="default" size="100%">Moraceae</style></keyword><keyword><style  face="normal" font="default" size="100%">SOD Assay</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">JUN</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">6</style></number><publisher><style face="normal" font="default" size="100%">AMER SCIENTIFIC PUBLISHERS</style></publisher><pub-location><style face="normal" font="default" size="100%">26650 THE OLD RD, STE 208, VALENCIA, CA 91381-0751 USA</style></pub-location><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">1221-1226</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Ficus religiosa (Sacred Fig) is a medicinally important tree, native to the Indian subcontinent. It has been extensively pharmacologically researched species having wide spectrum of medicinal properties. All parts of F. religiosa tree are known to possess important medicinal properties such as anti-oxidant, anti-inflammatory, wound healing and skin diseases etc. However, effects of F. religiosa on skin cells line HaCaT was not studied for its antioxidant properties. In this report we have investigated F. religiosa bark aqueous extract for its antioxidant properties on human keratinocytes (HaCaT) cell line using DPPH, superoxide dismutase 1, superoxide dismutase 2 and catalase assay. We observed that F. religiosa bark aqueous extract efficiently scavenged (80%) DPPH radicals. Superoxide dismutase1 assay of F. religiosa bark aqueous extract effectively scavenged superoxide radicals (O-2(-)) and showed dose dependent activity. Reactive oxygen species were trapped by superoxide dismutase 2 assay of F. religiosa bark aqueous extract and form hydrogen peroxide. Catalase assay results revelled that hydrogen peroxide was further decomposed to give water and oxygen. Thus various anti-oxidant assays of F. religiosa bark aqueous extract indicate that it efficiently reduced the reactive oxygen species in skin cells.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><custom3><style face="normal" font="default" size="100%">&lt;p&gt;Foreign&lt;/p&gt;</style></custom3><custom4><style face="normal" font="default" size="100%">1.812</style></custom4></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Pandey, Prem</style></author><author><style face="normal" font="default" size="100%">Seo, Hyo Hyun</style></author><author><style face="normal" font="default" size="100%">Kim, Hye-In</style></author><author><style face="normal" font="default" size="100%">Ryu, Seung Hwan</style></author><author><style face="normal" font="default" size="100%">Dingre, Medini</style></author><author><style face="normal" font="default" size="100%">Moh, Sang Hyun</style></author><author><style face="normal" font="default" size="100%">Kulkarni, Atul</style></author><author><style face="normal" font="default" size="100%">Parasharami, Varsha A.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Enhanced anti-ageing and wound healing properties of Ficus religiosa L. bark, leaf and aerial root extract in human keratinocytes cell line (HaCaT)</style></title><secondary-title><style face="normal" font="default" size="100%">Vegetos</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">JAN</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">33</style></volume><pages><style face="normal" font="default" size="100%">158-165</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;span style=&quot;color: rgb(51, 51, 51); font-family: Georgia, Palatino, serif; font-size: 18px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; background-color: rgb(252, 252, 252);&quot;&gt;Plants have played a vital role in curative and preventive healthcare.&amp;nbsp;&lt;/span&gt;&lt;i style=&quot;box-sizing: inherit; color: rgb(51, 51, 51); font-family: Georgia, Palatino, serif; font-size: 18px; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; background-color: rgb(252, 252, 252);&quot;&gt;Ficus religiosa&lt;/i&gt;&lt;span style=&quot;color: rgb(51, 51, 51); font-family: Georgia, Palatino, serif; font-size: 18px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; background-color: rgb(252, 252, 252);&quot;&gt;&amp;nbsp;L., a medicinally important tree has been used as a traditional medicine to treat various ailments and skin diseases. However, its skin anti-ageing properties are not yet scientifically evaluated. Here we report the comparison of&amp;nbsp;&lt;/span&gt;&lt;i style=&quot;box-sizing: inherit; color: rgb(51, 51, 51); font-family: Georgia, Palatino, serif; font-size: 18px; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; background-color: rgb(252, 252, 252);&quot;&gt;F. religiosa&lt;/i&gt;&lt;span style=&quot;color: rgb(51, 51, 51); font-family: Georgia, Palatino, serif; font-size: 18px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; background-color: rgb(252, 252, 252);&quot;&gt;&amp;nbsp;bark (FRAqB), leaf (FRAqL) and aerial-roots (FRAqAR) extracts for skin anti-ageing and wound healing properties. FRAqB, FRAqL and FRAqAR extracts preparation, cell culture, RNA isolation, real time PCR, astringent activity and wound healing assay were carried out using standard methods. Axio Observer FL-microscope and ImageJ software were used for wound healing assay analysis. The real time PCR study reveals that matrix metalloproteinase-1 (MMP) RNA was downregulated to 75% and 95% for FRAqB and FRAqAR, respectively. For procollagen C-endopeptidase enhancer 1 (PCOLCE), FRAqB and FRAqL enhanced RNA levels by 500% and 300%, respectively. FRAqB and FRAqL increased wound healing area to about 60% and FRAqAR by 50%. All three extracts demonstrated astringent activity which is significant for skin tightening. The study proves that extracts of&amp;nbsp;&lt;/span&gt;&lt;i style=&quot;box-sizing: inherit; color: rgb(51, 51, 51); font-family: Georgia, Palatino, serif; font-size: 18px; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; background-color: rgb(252, 252, 252);&quot;&gt;F. religiosa&lt;/i&gt;&lt;span style=&quot;color: rgb(51, 51, 51); font-family: Georgia, Palatino, serif; font-size: 18px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; background-color: rgb(252, 252, 252);&quot;&gt;&amp;nbsp;are prominent candidates for pharmaceutical and cosmetic applications such as skin anti-ageing and wound healing.&lt;/span&gt;&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Article</style></work-type><custom3><style face="normal" font="default" size="100%">&lt;p&gt;Foreign&lt;/p&gt;</style></custom3><custom4><style face="normal" font="default" size="100%">&lt;p&gt;0.40&lt;/p&gt;</style></custom4></record></records></xml>