<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Athawale, Paresh R</style></author><author><style face="normal" font="default" size="100%">Kumari, Neeta</style></author><author><style face="normal" font="default" size="100%">Kashinath, K</style></author><author><style face="normal" font="default" size="100%">Reddy, D. Srinivasa</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Synthesis of chiral tetrahydrofuran building blocks from pantolactones: application in the synthesis of empagliflozin and amprenavir analogs</style></title><secondary-title><style face="normal" font="default" size="100%">Europen Journal of Organic Chemistry</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">JUL</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;span class=&quot;hitHilite&quot;&gt;Chiral&lt;/span&gt; 4,4-dimethyl &lt;span class=&quot;hitHilite&quot;&gt;tetrahydrofuran&lt;/span&gt; (THF) derivatives were synthesized &lt;span class=&quot;hitHilite&quot;&gt;from&lt;/span&gt; commercially available D-(-)/ l-(+) &lt;span class=&quot;hitHilite&quot;&gt;pantolactones&lt;/span&gt;, which can serve as &lt;span class=&quot;hitHilite&quot;&gt;chiral&lt;/span&gt; &lt;span class=&quot;hitHilite&quot;&gt;building&lt;/span&gt; &lt;span class=&quot;hitHilite&quot;&gt;blocks&lt;/span&gt; &lt;span class=&quot;hitHilite&quot;&gt;in&lt;/span&gt; medicinal chemistry. &lt;span class=&quot;hitHilite&quot;&gt;In&lt;/span&gt; addition, two &lt;span class=&quot;hitHilite&quot;&gt;of&lt;/span&gt; &lt;span class=&quot;hitHilite&quot;&gt;the&lt;/span&gt; synthesized &lt;span class=&quot;hitHilite&quot;&gt;building&lt;/span&gt; &lt;span class=&quot;hitHilite&quot;&gt;blocks&lt;/span&gt; were utilized &lt;span class=&quot;hitHilite&quot;&gt;for&lt;/span&gt; &lt;span class=&quot;hitHilite&quot;&gt;the&lt;/span&gt; &lt;span class=&quot;hitHilite&quot;&gt;synthesis&lt;/span&gt; &lt;span class=&quot;hitHilite&quot;&gt;of&lt;/span&gt; new &lt;span class=&quot;hitHilite&quot;&gt;amprenavir&lt;/span&gt; (HIV protease inhibitor) and &lt;span class=&quot;hitHilite&quot;&gt;empagliflozin&lt;/span&gt; (anti-diabetic) &lt;span class=&quot;hitHilite&quot;&gt;analogs&lt;/span&gt;. &lt;span class=&quot;hitHilite&quot;&gt;The&lt;/span&gt; synthesized &lt;span class=&quot;hitHilite&quot;&gt;analogs&lt;/span&gt; may have beneficial effects &lt;span class=&quot;hitHilite&quot;&gt;in&lt;/span&gt; terms &lt;span class=&quot;hitHilite&quot;&gt;of&lt;/span&gt; pharmacokinetics and modulation &lt;span class=&quot;hitHilite&quot;&gt;of&lt;/span&gt; bioactivity.&lt;/p&gt;
</style></abstract><work-type><style face="normal" font="default" size="100%">Article</style></work-type><custom3><style face="normal" font="default" size="100%">&lt;p&gt;Foreign&lt;/p&gt;
</style></custom3><custom4><style face="normal" font="default" size="100%">&lt;p&gt;&lt;span class=&quot;info_value&quot;&gt;3.029&lt;/span&gt;&lt;/p&gt;
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