02099nas a2200241 4500008004100000022001400041245016700055210006900222260007300291300001200364490000800376520114000384653003001524653003101554653002101585653003401606653001801640653001701658100001801675700001601693700001701709856013101726 2005 eng d a0926-860X00aZeolite-based organic-inorganic hybrid catalysts for phosgene-free and solvent-free synthesis of cyclic carbonates and carbamates at mild conditions utilizing CO20 aZeolitebased organicinorganic hybrid catalysts for phosgenefree  aPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSbELSEVIER SCIENCE BVcAUG a128-1340 v2893 a

As-synthesized zeolite-beta exhibits high catalytic activity for the synthesis of cyclic carbonates and alkyl and aryl carbarnates by a phosgene-free route, utilizing the greenhouse effect gas CO2. The reaction occurs with high yields of the desired products at mild conditions and without using any solvent or cocatalyst. Cyclic carbonates are synthesized by cycloaddition reaction Of CO2 with oxiranes (epichlorohydrin, propene oxide, styrene oxide and n-butene oxide) at 393 K and 6.9 bar. Alkyl and aryl carbarnates are synthesized by the reaction of the corresponding amines, CO2 and n-butyl bromide at 353 K and 3.4 bar. The as-synthesized zeolite-beta containing the encapsulated quaternary ammonium ions is not only reusable in several recycling experiments, but also shows superior activity to that of the corresponding homogeneous, quaternary ammonium halide salt generally used in the commercial synthetic practice. The microporous silica (inorganic) acting in concert with the encapsulated organic component constitutes an efficient, recyclable catalyst for this reaction. (c) 2005 Elsevier B.V. All rights reserved.

10aalkyl and aryl carbamates10acarbon dioxide utilization10acyclic carbonate10aphosgene-free synthetic route10aPolycarbonate10azeolite-beta1 aSrivastava, R1 aSrinivas, D1 aRatnasamy, P uhttps://library.ncl.res.in/content/zeolite-based-organic-inorganic-hybrid-catalysts-phosgene-free-and-solvent-free-synthesis-002372nas a2200217 4500008004100000022001400041245011200055210006900167260009500236300000900331490000800340520152800348653003001876653002501906653001901931653001301950100002201963700001701985700002802002856012402030 2005 eng d a0021-951700aZirconia-supported 12-tungstophosphoric acid as a solid catalyst for the synthesis of linear alkyl benzenes0 aZirconiasupported 12tungstophosphoric acid as a solid catalyst f a525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USAbACADEMIC PRESS INC ELSEVIER SCIENCEcAPR a1-100 v2313 a

The liquid-phase alkylation of benzene with 1-octene and 1-dodecene was investigated with zirconia-supported 12-tungstophosphoric acid (TPA) as catalysts. We prepared the catalysts, with different TPA loading (5-20 wt% calcined at 750 degrees C) and calcination temperatures (15 wt% calcined from 650 to 850 degrees C), by suspending hydrous zirconia in a methanol solution of TPA, followed by drying and calcination. These catalysts were characterized by X-ray diffraction, DTG-DTA, FTIR pyridine adsorption, NH3-TPD, and P-31, MAS NMR spectroscopy measurements. The catalyst with optimum TPA loading (15%) and calcination temperature (750 degrees C) was prepared in different solvents and characterized by P-31 MAS NMR spectroscopy. The XRD results indicate that TPA stabilizes the tetragonal phase of zirconia. The catalysts show both Bronsted and Lewis acidity, and 15% TPA on zirconia calcined at 750 degrees C shows the highest acidity. P-31 MAS NMR spectra show two types of phosphorous species: one is the Keggin unit and the other is the decomposition product of TPA. The relative amount of each depends on TPA loading, calcination temperature, and the solvent used for the catalyst preparation. Under reaction conditions of 84 degrees C and a benzene/1-olefin molar ratio of 10 (time 1 h), the most active catalyst, 15% TPA, calcined at 750 degrees C, gave more than 98% olefin conversion with selectivity for 2-phenyl octane (53.5%) and 2-phenyl dodecane (47%). (c) 2004 Elsevier Inc. All rights reserved.

10a12-tungstophosphoric acid10alinear alkyl benzene10asolvent effect10aZirconia1 aDevassy, Biju, M.1 aLefebvre, F.1 aHalligudi, Shivaraj, B. uhttps://library.ncl.res.in/content/zirconia-supported-12-tungstophosphoric-acid-solid-catalyst-synthesis-linear-alkyl-002048nas a2200253 4500008004100000022001400041245010100055210006900156260007300225300001200298490000800310520115200318653001601470653001101486653002501497653001301522100002201535700002101557700001701578700002201595700002601617700002801643856012301671 2005 eng d a1381-116900aZirconia-supported phosphotungstic acid as catalyst for alkylation of phenol with benzyl alcohol0 aZirconiasupported phosphotungstic acid as catalyst for alkylatio aPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSbELSEVIER SCIENCE BVcAPR a113-1190 v2303 a

The liquid-phase alkylation of phenol with benzyl alcohol was carried out using zirconia-supported phosphotungstic acid (PTA) as catalyst. The catalysts with different PTA loadings (5-20 wt.% calcined at 750 degrees C) and calcination temperature (15 wt.% calcined from 650 to 850 degrees C) were prepared and characterized by (31)p MAS NMR and FT-IR pyridine adsorption spectroscopy. The catalyst with optimum PTA loading (15%) and calcination temperature (750 degrees C) was prepared in different solvents. 31p MAS NMR spectra of the catalysts showed two types of phosphorous species, one is the Keggin unit and the other is the decomposition product of PTA and the relative amount of each depends on PTA loading, calcination temperature and the solvent used for the catalyst preparation. The catalysts with 15% PTA on zirconia calcined at 750 degrees C showed the highest Bronsted acidity. At 130 degrees C and phenol/benzyl alcohol molar ratio of 2 (time, I h), the most active catalyst, 15% PTA calcined at 750 degrees C gave 98% benzyl alcohol conversion with 83% benzyl phenol selectivity. (c) 2004 Elsevier B.V. All rights reserved.

10aBenzylation10aphenol10aPhosphotungstic acid10aZirconia1 aDevassy, Biju, M.1 aShanbhag, G., V.1 aLefebvre, F.1 aBohringer, Walter1 aFletcher, Jack, C. Q.1 aHalligudi, Shivaraj, B. uhttps://library.ncl.res.in/content/zirconia-supported-phosphotungstic-acid-catalyst-alkylation-phenol-benzyl-alcohol-001822nas a2200217 4500008004100000022001400041245010200055210006900157260007100226300001600297490000800313520099800321100002501319700002401344700002101368700002301389700002201412700002001434700002201454856012801476 2006 eng d a1520-610600aZnO multipods, submicron wires, and spherical structures and their unique field emission behavior0 aZnO multipods submicron wires and spherical structures and their a1155 16TH ST, NW, WASHINGTON, DC 20036 USAbAMER CHEMICAL SOCcSEP a18236-182420 v1103 a

A simple method of vapor deposition for the shape selective synthesis of ZnO structures, namely, multipods, submicron wires, and spheres, has been successfully demonstrated. A plausible growth mechanism based on the studies of scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS) is proposed. Our studies suggest that the growth of a multipod structure is governed by the screw dislocation propagation while the vapor-liquid-solid (VLS) mechanism is responsible for the formation of submicron wires and spheres. Moreover, the flow rate of the carrier gas plays a crucial role in governing the morphology. Further, these structures exhibit an enhanced field emission behavior. The nonlinearity in the Fowler-Nordheim (F-N) plot, a characteristic feature of electron emission from semiconductors, is explained by considering the contributions from both the conduction and the valence bands of ZnO.

1 aRamgir, Niranjan, S.1 aLate, Dattatray, J.1 aBhise, Ashok, B.1 aMore, Mahendra, A.1 aMulla, Imtiaz, S.1 aJoag, Dilip, S.1 aVijayamohanan, K. uhttps://library.ncl.res.in/content/zno-multipods-submicron-wires-and-spherical-structures-and-their-unique-field-emission-001768nas a2200193 4500008004100000022001400041245009000055210006900145260007100214300001400285490000700299520105500306100001801361700001501379700002801394700001701422700001901439856011601458 2007 eng d a0743-746300aZirconia enrichment in zircon sand by selective fungus-mediated bioleaching of silica0 aZirconia enrichment in zircon sand by selective fungusmediated b a1155 16TH ST, NW, WASHINGTON, DC 20036 USAbAMER CHEMICAL SOCcAPR a4993-49980 v233 a

One of the important routes for the production of zirconia is by chemical treatment and removal of silica from zircon sand (ZrSixOy). We present here a completely green chemistry approach toward enrichment of zirconia in zircon sand; this is based on the reaction of the fungus Fusarium oxysporum with zircon sand by a process of selective extracellular bioleaching of silica nanoparticles. Since this reaction does not result in zirconia being simultaneously leached out from the sand, there is a consequent enrichment of the zirconia component in zircon sand. We believe that fungal enzymes specifically hydrolyze the silicates present in the sand to form silicic acid, which on condensation by certain other fungal enzymes results in room-temperature synthesis of silica nanoparticles. This fungus-mediated twofold approach might have vast commercial implications in low-cost, ecofriendly, room-temperature syntheses of technologically important oxide nanomaterials from potentially cheap naturally available raw materials like zircon sand.

1 aBansal, Vipul1 aSyed, Asad1 aBhargava, Suresh, Kumar1 aAhmad, Absar1 aSastry, Murali uhttps://library.ncl.res.in/content/zirconia-enrichment-zircon-sand-selective-fungus-mediated-bioleaching-silica02292nas a2200217 4500008004100000022001400041245006300055210006200118260012500180300001100305490000800316520150400324100002001828700001801848700001901866700001701885700002501902700002701927700002301954856009701977 2008 eng d a0021-897900aZinc oxide nanoparticles as novel alpha-amylase inhibitors0 aZinc oxide nanoparticles as novel alphaamylase inhibitors aCIRCULATION & FULFILLMENT DIV, 2 HUNTINGTON QUADRANGLE, STE 1 N O 1, MELVILLE, NY 11747-4501 USAbAMER INST PHYSICScNOV a0949070 v1043 a

Amylase inhibitors, also known as starch blockers, contain substances that prevent dietary starches from being absorbed by the body via inhibiting breakdown of complex sugars to simpler ones. In this sense, these materials are projected as having potential applications in diabetes control. In this context, we report on zinc oxide nanoparticles as possible alpha-amylase inhibitors. Zinc oxide nanoparticles have been synthesized using soft-chemistry approach and 1-thioglycerol was used as a surfactant to yield polycrystalline nanoparticles of size similar to 18 nm, stabilized in wurtzite structure. Conjugation study and structural characterization have been done using x-ray diffraction technique, Fourier transform infrared spectroscopy, UV-visible spectroscopy, and transmission electron microscopy. Cytotoxicity studies on human fibrosarcoma (HT-1080) and skin carcinoma (A-431) cell lines as well as mouse primary fibroblast cells demonstrate that up to a dose of 20 mu g/ml, ZnO nanoparticles are nontoxic to the cells. We report for the first time the alpha-amylase inhibitory activity of ZnO nanoparticles wherein an optimum dose of 20 mu g/ml was sufficient to exhibit 49% glucose inhibition at neutral pH and 35 degrees C temperature. This inhibitory activity was similar to that obtained with acarbose (a standard alpha-amylase inhibitor), thereby projecting ZnO nanoparticles as novel alpha-amylase inhibitors. (C) 2008 American Institute of Physics. [DOI: 10.1063/1.3009317]

1 aDhobale, Sandip1 aThite, Trupti1 aLaware, S., L.1 aRode, C., V.1 aKoppikar, Soumya, J.1 aGhanekar, Ruchika-Kaul1 aKale, Sangeeta, N. uhttps://library.ncl.res.in/content/zinc-oxide-nanoparticles-novel-alpha-amylase-inhibitors-001402nas a2200241 4500008004100000022001400041245012500055210006900180260007900249300001200328490000700340520046400347653001800811653002200829653002700851653002100878100002400899700002800923700002600951700002500977700002601002856013201028 2010 eng d a1001-841700aZnO-beta zeolite: as an effective and eco-friendly heterogeneous catalyst for the synthesis of benzothiazole derivatives0 aZnObeta zeolite as an effective and ecofriendly heterogeneous ca a360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USAbELSEVIER SCIENCE INCcAPR a421-4250 v213 a

A cheap and recyclable ZnO-beta zeolite was used as catalyst for the synthesis of benzothiazole derivatives. This method provides several advantages such as environmental friendliness, short reaction times, high yields, simple work-up procedure and catalyst was successfully reused for four cycles without significant loss of activity. (C) 2009 Machhindra K. Lande. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

10aBenzothiazole10acyclocondensation10aheterogeneous catalyst10aZnO-beta zeolite1 aKatkar, Santosh, S.1 aMohite, Pravinkumar, H.1 aGadekar, Lakshman, S.1 aVidhate, Kaluram, N.1 aLande, Machhindra, K. uhttps://library.ncl.res.in/content/zno-beta-zeolite-effective-and-eco-friendly-heterogeneous-catalyst-synthesis-benzothiazole-001511nas a2200241 4500008004100000022001400041245012300055210006900178260009200247300001200339490000600351520056800357653002600925653002700951653001900978653002100997100002401018700002801042700002601070700002501096700002601121856012201147 2010 eng d a1751-825300aZnO-beta zeolite: as an effective and reusable heterogeneous catalyst for the one-pot synthesis of polyhydroquinolines0 aZnObeta zeolite as an effective and reusable heterogeneous catal a4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLANDbTAYLOR & FRANCIS LTDcDEC a287-2920 v33 a

ZnO-beta zeolite, an inexpensive and mild catalyst, has been used for the synthesis of polyhydroquinolines in excellent yields from the one-pot four-component condensation of aldehydes, dimedone, ethyl acetoacetate, and ammonium acetate in ethanol at room temperature. The remarkable advantages offered by this method are a green catalyst, mild reaction conditions, simple work-up procedures, much faster reactions, and excellent yield of products. Furthermore, the catalyst could be reused several times keeping its initial activity in recycled reactions.

10aHantzsch condensation10aheterogeneous catalyst10amulticomponent10aZnO-beta zeolite1 aKatkar, Santosh, S.1 aMohite, Pravinkumar, H.1 aGadekar, Lakshman, S.1 aArbad, Balasaheb, R.1 aLande, Machhindra, K. uhttps://library.ncl.res.in/content/zno-beta-zeolite-effective-and-reusable-heterogeneous-catalyst-one-pot-synthesis-001329nas a2200241 4500008004100000022001400041245013100055210006900186260005600255300001200311490000600323520042400329653002200753653001600775653002100791653002100812100002400833700002800857700002600885700002500911700002600936856012500962 2010 eng d a1895-106600aZnO-beta zeolite mediated simple and efficient method for the one-pot synthesis of quinoxaline derivatives at room temperature0 aZnObeta zeolite mediated simple and efficient method for the one aSOLIPSKA 14A-1, 02-482 WARSAW, POLANDbVERSITAcAPR a320-3250 v83 a

A rapid and an efficient one-pot method for the synthesis of quinoxalines catalysed by ZnO-beta zeolite at room temperature is described. This environmentally benign method provides several advantages over methods that are currently employed such as a simple work-up, mild reaction conditions, good to excellent yields, and a process to recover and reuse the catalyst for several cycles with consistent activity.

10acyclocondensation10aQuinoxaline10aRoom temperature10aZnO-beta zeolite1 aKatkar, Santosh, S.1 aMohite, Pravinkumar, H.1 aGadekar, Lakshman, S.1 aArbad, Balasaheb, R.1 aLande, Machhindra, K. uhttps://library.ncl.res.in/content/zno-beta-zeolite-mediated-simple-and-efficient-method-one-pot-synthesis-quinoxaline-000954nas a2200169 4500008004100000245013800041210006900179260000800248300001400256490000700270520029900277100001800576700002600594700002000620700001700640856012700657 2011 eng d00aZn(II) and Cd(II)-based complexes for probing the enzymatic hydrolysis of Na4P2O7 by alkaline phosphatase in physiological conditions0 aZnII and CdIIbased complexes for probing the enzymatic hydrolysi cSEP a8118-81200 v473 a

Newly synthesized Zn(II) and Cd(II)-based complexes show unique selectivity towards inorganic pyrophosphate (PPi) in 100% aqueous medium at pH = 7.4 and act as a "turn-on" and "turn-off" real-time assay, respectively, for the evaluation of the enzymatic activity of alkaline phosphatase.

1 aDas, Priyadip1 aSourish, Bhattacharya1 aSandhya, Mishra1 aDas, Amitava uhttps://library.ncl.res.in/content/znii-and-cdii-based-complexes-probing-enzymatic-hydrolysis-na4p2o7-alkaline-phosphatase01418nas a2200181 4500008004100000245009400041210006900135260000800204300001600212520077500228100001801003700001801021700002601039700001601065700002301081700001701104856011501121 2011 eng d00aZnII-2,2?:6?,2?-terpyridine-based complex as fluorescent chemosensor for PPi, AMP and ADP0 aZnII2262terpyridinebased complex as fluorescent chemosensor for  cJUL a3050–30583 a

A new ZnII–2,2′:6′,2″-terpyridine complex, derivatized with a coumarin moiety (L1Zn), acts as a fluorescent chemosensor for different biologically important phosphates like PPi, AMP and ADP in mixed aqueous media. Depending on the proportion of the aqueous fraction present in the solvent mixture, L1Zn shows a preference for different phosphate moieties at physiological pH. In an aqueous acetonitrile (2:3, v/v) medium this reagent shows a preference for AMP as compared to ADP, ATP and PPi. The binding affinities of L1Zn with different phosphate ions and associated shifts in the electronic spectra were rationalized by DFT calculations. Such an example of a receptor that is selective for AMP under physiological conditions is rare in the literature.

1 aDas, Priyadip1 aGhosh, Amrita1 aKesharwani, Manoj, K.1 aRamu, Vadde1 aGanguly, Bishwajit1 aDas, Amitava uhttps://library.ncl.res.in/content/znii-2262-terpyridine-based-complex-fluorescent-chemosensor-ppi-amp-and-adp01794nas a2200193 4500008004100000245018400041210006900225260000800294300001600302490000700318520102100325100002201346700001801368700002301386700002401409700002001433700001701453856013001470 2011 eng d00aZn(II)-cyclam based chromogenic sensors for recognition of atp in aqueous solution under physiological conditions and their application as viable staining agents for microorganism0 aZnIIcyclam based chromogenic sensors for recognition of atp in a cMAR a4162–41700 v503 a

Two chromogenic complexes, L.Zn (where L is (E)-4-((4-(1,4,8,11-tetraazacyclotetradecan-1-ylsulfonyl)phenyl)diazenyl)-N,N-dimethylaniline) and its [2]pseudorotaxane form (α-CD.L.Zn), were found to bind preferentially to adenosine triphosphate (ATP), among all other common anions and biologically important phosphate (AMP, ADP, pyrophosphate, and phosphate) ions in aqueous HEPES buffer medium of pH 7.2. Studies with live cell cultures of prokaryotic microbes revealed that binding of these two reagents to intercellular ATP, produced in situ, could be used in delineating the Gram-positive and the Gram-negative bacteria. More importantly, these dyes were found to be nontoxic to living microbes (eukaryotes and prokaryotes) and could be used for studying the cell growth dynamics. Binding to these two viable staining agents to intercellular ATP was also confirmed by spectroscopic studies on cell growth in the presence of different respiratory inhibitors that influence the intercellular ATP generation.

1 aMahato, Prasenjit1 aGhosh, Amrita1 aMishra, Sanjiv, K.1 aShrivastav, Anupama1 aMishra, Sandhya1 aDas, Amitava uhttps://library.ncl.res.in/content/znii-cyclam-based-chromogenic-sensors-recognition-atp-aqueous-solution-under-physiological02064nas a2200253 4500008004100000022001400041245013500055210006900190260009300259300001200352490000700364520103800371653004301409653003301452653001301485653003701498100002501535700002301560700002401583700002501607700002301632700002501655856013001680 2012 eng d a1469-066700aZoom-in - a targeted database search for identification of glycation modifications analyzed by untargeted tandem mass spectrometry0 aZoomin a targeted database search for identification of glycatio a6 CHARLTON MILL, CHARLTON, CHICHESTER,, W SUSSEX PO18 0HY, ENGLANDbIM PUBLICATIONScJAN a475-4810 v183 a

Post-translational modifications (PTMs) are very important to biological function, however their identification and characterization is technically challenging. In this study, we have identified glycation modifications by nano LC-MSE, a data independent acquisition work flow, followed by database search using the Protein Lynx Global Server (PLGS). PLGS search with a complete human protein database hardly identified glycation modifications in a glycated human serum albumin (HSA), which was detected to be glycated by western blotting with advanced glycation end products (AGE) antibody and fluorescence spectroscopy. To overcome this difficulty, ``Zoom-In'' approach, a targeted database search was used to identify glycation modifications in a glycated HSA, which were further manually validated. This approach was useful for identification of glycation modifications from untargeted tandem mass spectrometry workflow such as MSE, but may require the development of a new algorithm or an upgrade of the existing software.

10aadvanced glycation end products (AGEs)10adata independent acquisition10aDiabetes10apost-translational modifications1 aBhonsle, Hemangi, S.1 aKorwar, Arvind, M.1 aKesavan, Suresh, K.1 aBhosale, Santosh, D.1 aBansode, Sneha, B.1 aKulkarni, Mahesh, J. uhttps://library.ncl.res.in/content/zoom-targeted-database-search-identification-glycation-modifications-analyzed-untargeted-002881nas a2200241 4500008004100000022001400041245014000055210006900195260007700264300001400341490000700355520195300362653001102315653002102326653002902347653001902376653003002395100002902425700002302454700002002477700002402497856011802521 2013 eng d a0947-653900aZeolitic imidazolate framework (ZIF)-derived, hollow-core, nitrogen-doped carbon nanostructures for oxygen-reduction reactions in PEFCs0 aZeolitic imidazolate framework ZIFderived hollowcore nitrogendop aBOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANYbWILEY-V C H VERLAG GMBHcJUL a9335-93420 v193 a

The facile synthesis of a porous carbon material that is doped with iron-coordinated nitrogen active sites (FeNC-70) is demonstrated by following an inexpensive synthetic pathway with a zeolitic imidazolate framework (ZIF-70) as a template. To emphasize the possibility of tuning the porosity and surface area of the resulting carbon materials based on the structure of the parent ZIF, two other ZIFs, that is, ZIF-68 and ZIF-69, are also synthesized. The resulting active carbon material that is derived from ZIF-70, that is, FeNC-70, exhibits the highest BET surface area of 262m2g-1 compared to the active carbon materials that are derived from ZIF-68 and ZIF-69. The HR-TEM images of FeNC-70 show that the carbon particles have a bimodal structure that is composed of a spherical macroscopic pore (about 200nm) and a mesoporous shell. X-ray photoelectron spectroscopy (XPS) reveals the presence of Fe-N-C moieties, which are the primary active sites for the oxygen-reduction reaction (ORR). Quantitative estimation by using EDAX analysis reveals a nitrogen content of 14.5wt.%, along with trace amounts of iron (0.1wt.%), in the active FeNC-70 catalyst. This active porous carbon material, which is enriched with Fe-N-C moieties, reduces the oxygen molecule with an onset potential at 0.80V versus NHE through a pathway that involves 3.3-3.8e- under acidic conditions, which is much closer to the favored 4e- pathway for the ORR. The onset potential of FeNC-70 is significantly higher than those of its counterparts (FeNC-68 and FeNC-69) and of other reported systems. The FeNC-based systems also exhibit much-higher tolerance towards MeOH oxidation and electrochemical stability during an accelerated durability test (ADT). Electrochemical analysis and structural characterizations predict that the active sites for the ORR are most likely to be the insitu generated NFeN2+2/C moieties, which are distributed along the carbon framework.

10aDoping10aElectrochemistry10ametal-organic frameworks10aNanostructures10aoxygen-reduction reaction1 aPalaniselvam, Thangavelu1 aBiswal, Bishnu, P.1 aBanerjee, Rahul1 aKurungot, Sreekumar uhttps://library.ncl.res.in/content/zeolitic-imidazolate-framework-zif-derived-hollow-core-nitrogen-doped-carbon-001826nas a2200241 4500008004100000022001400041245013200055210006900187260007300256300001200329490000800341520087800349653001801227653003301245653002601278653003601304653001801340653004301358100002001401700002301421700001701444856012301461 2013 eng d a0926-860X00aZirconium phenyl phosphonate phosphite as a highly active, reusable, solid acid catalyst for producing fatty acid polyol esters0 aZirconium phenyl phosphonate phosphite as a highly active reusab aPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSbELSEVIER SCIENCE BVcJUL a129-1360 v4623 a

The application of zirconium phenyl phosphonate phosphite (ZrPP) as a solid acid catalyst for producing polyol esters by esterification of glycerol or trimethylolpropane with a fatty acid (C-8-C-18.1) is reported for the first time. ZrPP exhibits high catalytic activity and in particular, (di + tri) esters selectivity (92.3 mol%). These esters of polyols are known for their application as biolubricants. The catalyst prepared using phosphorous acid to phenyl phosphonic acid molar ratio of 3:1 was found superior. The influence of process parameters on activity and selectivity of the catalyst was investigated. ZrPP was reusable in at least three recycling experiments. Hydrophobicity due to exposed phenyl groups on the surface is the possible cause for superior esterification activity of this novel, solid catalyst. (C) 2013 Elsevier B.V. All rights reserved.

10aBiolubricants10aEsterification of fatty acid10aFatty acid glycerides10aHydrophobic solid acid catalyst10aPolyol esters10aZirconium phenyl phosphonate phosphite1 aVarhadi, Poonam1 aKotwal, Mehejabeen1 aSrinivas, D. uhttps://library.ncl.res.in/content/zirconium-phenyl-phosphonate-phosphite-highly-active-reusable-solid-acid-catalyst-001773nas a2200169 4500008004100000022001400041245011400055210006900169260011000238300001600348490000600364520104100370100001901411700002001430700002201450856013101472 2014 eng d a2050-748800aZIF-8@PBI-Bul composite membranes: elegant effects of PBI structural variations on gas permeation performance0 aZIF8PBIBul composite membranes elegant effects of PBI structural aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcAUG a12962-129670 v23 a

The composites of metal organic frameworks (MOFs) and polymers look promising as membrane materials for gas separation, provided benefits of both the components can be shown successfully. This work shows that the structural architecture of polybenzimidazole (PBI) is highly advantageous in offering attractive gas permeation properties of its composites with MOFs. PBI-Bul and its N-substituted (methyl and 4-tert-butylbenzyl) derivatives were blended with ZIF-8. In general, homogeneous blend formation of ZIF-8 was achieved with all three polymers, as supported by SEM. Wide angle X-ray diffraction, mechanical property analysis and density measurements of the composite membranes were performed in order to understand the effects of physical blending of MOFs and polymers. Gas permeability analysis of the composite membranes revealed that the properties of MOFs as well as those of polymers arising from their structural architecture are responsible for governing the permeability and selectivity of the resulting composites.

1 aBhaskar, Anand1 aBanerjee, Rahul1 aKharul, Ulhas, K. uhttps://library.ncl.res.in/content/zif-8pbi-bul-composite-membranes-elegant-effects-pbi-structural-variations-gas-permeation-001115nas a2200157 4500008004100000022001400041245011900055210006900174260011000243300001400353490000700367520041500374100001800789700002100807856012900828 2014 eng d a1477-052000aZinc mediated allylations of chlorosilanes promoted by ultrasound: synthesis of novel constrained sila amino acids0 aZinc mediated allylations of chlorosilanes promoted by ultrasoun aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcMAY a4093-40970 v123 a

A simple, fast and efficient method for allylation and propargylation of chlorosilanes through zinc mediation and ultrasound promotion is reported. As a direct application of the resulting bis-allylsilanes, three novel, constrained sila amino acids are prepared for the first time. The design and synthesis of the constrained sila analogue of GABA (gamma-amino butyric acid) is a highlight of this work.

1 aRamesh, Remya1 aReddy, Srinivasa uhttps://library.ncl.res.in/content/zinc-mediated-allylations-chlorosilanes-promoted-ultrasound-synthesis-novel-constrained-002341nas a2200193 4500008004100000022001400041245010800055210006900163260000800232300001200240490000600252520166800258100001601926700001901942700001801961700002001979700002501999856012302024 2014 eng d a2040-336400aZnO(N)-Spiro-MeOTAD hybrid photodiode: an efficient self-powered fast-response UV (visible) photosensor0 aZnONSpiroMeOTAD hybrid photodiode an efficient selfpowered fastr cFEB a503-5130 v63 a

Organic-inorganic hybrid photo-detectors with a self-sufficient mode of operation represent a research area of great current interest. In most efficient photodetectors and optoelectronic devices compound semiconductors containing toxic elements such as Cd, As, Te, S, Se etc. are used and these are also expensive. Hence there is also a rapidly growing interest in replacing these with environmentally friendly and earth-abundant materials. Herein, we report a facile solution-processed fabrication of a self-powered organic-inorganic hybrid photodetector using n-type oriented ZnO nanorods and p-type Spiro-MeOTAD semiconductor. ZnO is eco-friendly and earth-abundant, and Spiro-MeOTAD is nonhazardous. We show that the latter has far less toxicity than the toxic elements stated above. This visible blind UV photodetector shows high sensitivity (10(2)) and a UV/visible rejection ratio of 300. It also exhibits fast response times of tau(rise) similar to 200 mu s and tau(fall) similar to 950 mu s. Importantly, with a small modification of nitrogen incorporation in ZnO one can also realize a highly-sensitive self-powered visible light photodetector with at least 1000% (or higher) improvements in quality factors (photocurrent/sensitivity/response time) as compared to previously reported organic-inorganic hybrid photo-detectors based on metal-chalcogenides (CdS-PANI or CuInSe2-P3HT). Interestingly, the broadband sensitivity of such N:ZnO-Spiro-MeOTAD photodiode enables sensing of low intensity (similar to 28 mu W cm(-2)) ambient white light with a high photocurrent density of 120 nA cm(-2) making it an efficient ambient white light detector.

1 aGame, Onkar1 aSingh, Upendra1 aKumari, Tanya1 aBanpurkar, Arun1 aOgale, Satishchandra uhttps://library.ncl.res.in/content/znon-spiro-meotad-hybrid-photodiode-efficient-self-powered-fast-response-uv-visible02227nas a2200265 4500008004100000022001400041245014100055210006900196260007300265300001200338490000700350520126500357653001201622653001701634653001401651100001701665700002101682700002201703700001801725700001901743700001701762700002701779700002501806856013001831 2015 eng d a0141-813000aZinc inhibits glycation induced structural, functional modifications in albumin and protects erythrocytes from glycated albumin toxicity0 aZinc inhibits glycation induced structural functional modificati aPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSbELSEVIER SCIENCE BVcAUG a601-6100 v793 a

The present work aims to investigate the concentration and time dependant effect of zinc on the in vitro non enzymatic modifications of albumin by diabetic levels of glucose. Further, preventive and curative effect of zinc was studied by adding zinc before and after initiation of glycation respectively. Glycation of albumin was done at different concentrations of zinc (125, 250 and 500 mu M) at different time intervals (21,28 and 35 days) with appropriate controls. The antiglycation potential of zinc was assessed by estimating different markers of albumin glycation (fructosamines, carbonyls, bound sugar, AGEs), structural modifications (free amino, thiol group, beta amyloid, native PAGE, ANS binding, fluorescence lifetime decay and CD analysis) and functional properties (antioxidant activity, hemolysis). Zinc at highest concentration (500 mu M) significantly reduced modifications of albumin which was comparable to aminoguanidine and also protected secondary and tertiary structure of albumin after 28 days of incubation. Zinc exhibited significant protective effect on erythrocytes by inhibiting hemolysis. Thus the present study indicate preventive mode of albumin glycation inhibition by zinc. (C) 2015 Elsevier B.V. All rights reserved.

10aAlbumin10aErythrocytes10aGlycation1 aTupe, Rashmi1 aKulkarni, Amruta1 aAdeshara, Krishna1 aSankhe, Neena1 aShaikh, Shamim1 aDalai, Sayli1 aBhosale, Siddharth, H.1 aGaikwad, Sushama, M. uhttps://library.ncl.res.in/content/zinc-inhibits-glycation-induced-structural-functional-modifications-albumin-and-protects-001673nas a2200109 4500008004100000245006400041210006400105260000800169520126100177100002401438856010101462 2017 eng d00aZiegler–Natta polymerization and the remaining challenges0 aZiegler–Natta polymerization and the remaining challenges cNOV3 aPolymers have become indispensable in the 21st century, and today we cannot imagine life without them. However, till around the beginning of the last century, the science of polymers was considered a very primitive discipline, and majority of the scientific community did not believe that polymers even existed. Hermann Staudinger, among others, fought a long battle to convince the scientific community that polymers are real and that they are long chain molecular entities. Building on this rational bedrock of polymer science, Prof. Karl Ziegler laid the foundation of ethylene polymerization. As outlined by Dr. Sivaram in his articles on Ziegler and Natta, careful observations and systematic analyses of serendipitous results enabled Ziegler to deveop the enormously significant ‘Mulheim atmospheric polyethylene process’. A decade later, ¨ Cossee and Arlman revealed the mechanism of this polymerization reaction, which is called ‘insertion polymerization’. Insertion polymerization is popularly known as the ‘Ziegler– Natta polymerization’, in recognition of its founding fathers. Today, the world produces about 180 million tons of polyolefins annually, and polyethylene or polythene has become a household name.1 aChikkali, Samir, H. uhttps://library.ncl.res.in/content/ziegler%E2%80%93natta-polymerization-and-remaining-challenges02335nas a2200193 4500008004100000245014800041210007100189260000800260300001600268490000600284520156000290100002201850700001701872700002901889700002401918700003001942700003001972856013902002 2017 eng d00aZnO–ZnS heterojunctions: a potential candidate for optoelectronics applications and mineralization of endocrine disruptors in direct sunlight0 aZnO–ZnS heterojunctions a potential candidate for optoelectronic cOCT a6768–67810 v23 a

Simple solution combustion synthesis was adopted to synthesize ZnO–ZnS (ZSx) nanocomposites using zinc nitrate as an oxidant and a mixture of urea and thiourea as a fuel. A large thiourea/urea ratio leads to more ZnS in ZSx with heterojunctions between ZnS and ZnO and throughout the bulk; tunable ZnS crystallite size and textural properties are an added advantage. The amount of ZnS in ZSx can be varied by simply changing the thiourea content. Although ZnO and ZnS are wide band gap semiconductors, ZSx exhibits visible light absorption, at least up to 525 nm. This demonstrates an effective reduction of the optical band gap and substantial changes in its electronic structure. Raman spectroscopy, transmission electron microscopy, X-ray photoelectron spectroscopy, and secondary-ion mass spectrometry results show features due to ZnO and ZnS and confirm the composite nature with heterojunctions. The above mentioned observations demonstrate the multifunctional nature of ZSx. Bare ZSx exhibits a promising sunlight-driven photocatalytic activity for complete mineralization of endocrine disruptors such as 2,4-dichlorophenol and endosulphan. ZSx also exhibits photocurrent generation at no applied bias. Dye-sensitized solar cell performance evaluation with ZSx shows up to 4% efficiency and 48% incident photon conversion efficiency. Heterojunctions observed between ZnO and ZnS nanocrystallites in high-resolution transmission electron microscopy suggest the reason for effective separation of electron–hole pairs and their utilization.

1 aDevaraji, Perumal1 aMapa, Maitri1 aHakkeem, Hasna, M. Abdul1 aSudhakar, Vediappan1 aKrishnamoorthy, Kothandam1 aGopinath, Chinnakonda, S. uhttps://library.ncl.res.in/content/zno%E2%80%93zns-heterojunctions-potential-candidate-optoelectronics-applications-and-mineralization02090nas a2200253 4500008004100000022001400041245007200055210006800127260000900195300001000204490000800214520130100222653001901523653003101542653002801573653001001601100002601611700001801637700001901655700001901674700002001693700002201713856010101735 2018 eng d a0376-738800aZIF-8@DBzPBI-BuI composite membranes for olefin/paraffin separation0 aZIF8DBzPBIBuI composite membranes for olefinparaffin separation cMAR  a38-450 v5493 aZIF-8 is a member of Zeolitic Imidazole Framework family having high internal surface area, the high thermo-chemical stability and ease of synthesis gained immense attention for its highly selective sieving ability. Transforming it into a membrane form and practical utility remains a challenge. Any success towards this direction would radically reduce the cost of propylene/propane separation. Present study reports use of substituted polybenzimidazole (DBzPBI-BuI) for fabrication of flexible, thus scalable composite membranes with ZIF-8 (ZIF8@DBzPBI-BuI) possessing host-guest compatibility. The membrane with 30% ZIF-8 loading showed promising propylene-propane separation (ideal selectivity of 32.7), coupled with propylene permeability of 12.13 Barrer. Analysis of sorption shed light on the high contribution of diffusivity on governing permeation properties of the composite membranes. The mixed gas analysis offered highly encouraging results in comparison to known composite membranes of different polymers with ZIF-8. Placement of present data on `upper-bound' showed a rapid enhancement in selectivity by the addition of ZIF-8 in the polymer matrix, which seems to be a result of the elimination of inter-phase defects. It was made possible due to the functionality of host polymer.10aGas permeation10aOlefin/paraffin separation10aPolybenzimidazole (PBI)10aZIF-81 aKunjattu, Shebeeb, H.1 aAshok, Varsha1 aBhaskar, Anand1 aPandare, Kiran1 aBanerjee, Rahul1 aKharul, Ulhas, K. uhttps://library.ncl.res.in/content/zif-8dbzpbi-bui-composite-membranes-olefinparaffin-separation02503nas a2200217 4500008004100000022001200041245008300053210006900136260000800205300000900213520182000222653001402042653001802056653001402074653001702088653000902105100001802114700002202132700001902154856011202173 2018 eng d a175759800aZinc supplementation decreases galactosylation of recombinant IgG in CHO cells0 aZinc supplementation decreases galactosylation of recombinant Ig cMAY a1-113 a

Trace element composition of culture medium can be altered to modulate glycoform of recombinant glycoproteins. In this study, we show that Zn2+ supplementation at or above 100 μM decreases galactosylation of recombinant IgG expressed in Chinese Hamster Ovary cells. This decrease in galactosylation is not due to reduced galactosyltransferase expression. This effect persists upon supplementation of galactose and uridine to the culture, indicating that it may not be due to reduced UDP-Gal availability. Measurements of galactosyltransferase activity in the cell lysate show that activity decreases with increasing Zn2+/Mn2+ ratio. This suggests that one possible explanation of the effect of Zn2+ may be reduced intracellular galactosyltransferase activity due to increase in Zn2+/Mn2+ ratio. Consistent with this, the decrease in galactosylation of IgG could be reversed by supplementation of Mn2+ (a cofactor of galactosyltransferase) which increases intracellular Mn2+ content. Measurement of total intracellular Zn2+ content, however, indicates no significant upregulation of total intracellular Zn2+ content and no significant downregulation of intracellular Mn2+ content with Zn2+ supplementation. One possible explanation could be that cellular detoxification response to higher extracellular Zn2+ concentration might lead to changes in intracellular distribution of Mn2+. In this case, Zn2+ supplementation would be expected to interfere with other known effects of Mn2+. Indeed, the previously reported increase in high mannose glycans upon Mn2+ supplementation in the absence of glucose is reversed by Zn2+ supplementation. This study also suggests the use of Mn2+ supplementation as a strategy to overcome the effect of lot-to-lot variability in trace element concentrations on galactosylation.

10aCHO cells10aglycosylation10amanganese10aTrace metals10azinc1 aPrabhu, Anuja1 aGadre, Ramchandra1 aGadgil, Mugdha uhttps://library.ncl.res.in/content/zinc-supplementation-decreases-galactosylation-recombinant-igg-cho-cells03126nas a2200205 4500008004100000022001400041245017200055210006900227260000800296300001400304490000600318520228000324653003502604653003002639653003002669653004102699100002402740700002402764856013202788 2018 eng d a2155-543500aZirconium-substituted cobalt ferrite nanoparticle supported n-doped reduced graphene oxide as an efficient bifunctional electrocatalyst for rechargeable Zn-air battery0 aZirconiumsubstituted cobalt ferrite nanoparticle supported ndope cAPR a3715-37260 v83 a

Solvothermal synthesis of zirconium-substituted cobalt ferrite nanoparticles was accomplished by the introduction of zirconium (Zr) in the spinel matrix to obtain a cost-effective and robust electrocatalyst that does not use noble metals. A variation in the cobalt ferrite structure CoFe2−xZrxO4 with Zr (0.1−0.4) substitution has significantly altered the overpotential for the electrocatalytic oxygen reduction reaction (ORR) and oxygen evolution reaction (OER), leading to an optimum composition of CFZr(0.3). The incorporation of the foreign Zr4+ ion in the cobalt ferrite spinel lattices has effectively enhanced the oxygen evolution reaction (OER) activity in comparison to the parent cobalt ferrite (CF) nanocrystals. However, a nominal change in the ORR current density has been observed due to Zr incorporation. For the OER, the Zr-substituted catalyst has shown a 40 mV negative shift in the overpotential in comparison with the CF nanoparticles at 10 mA/cm2 current density. Interestingly, the in situ grafting of Zr-substituted cobalt ferrite nanoparticles over N-doped reduced graphene oxide (CFZr(0.3)/N-rGO) results in remarkably enhanced performance during the ORR and moderately favored the OER with an overall potential difference (ΔE) of 0.840 V. The enhanced bifunctional electrocatalytic activity of the material is crucial for the fabrication of high-performance rechargeable Zn−air batteries (ZABs). The prepared catalyst exhibited an overpotential of 80 mV for the ORR in comparison with the state-of-the-art (Pt/C) catalyst and an overpotential of 340 mV at 10 mA/cm2 current density for the OER from the standard value (1.23 V vs RHE). This potential bifunctional electrocatalyst has been employed as an electrode material for the fabrication of a primary ZAB, where it exhibited discharge capacities of 727 and 730 mAh/g at current densities of 20 and 30 mA/cm2 , respectively, under ambient conditions. The notable performance of the catalyst as a bifunctional material is observed during the cycling of the rechargeable ZAB. The prepared catalyst showed an increase of 200 mV in the overall operating overpotential after cycling for 10 cycles at 15 mA/cm2 in comparison to the 350 mV increase shown by the Pt/C catalyst.

10aN-doped reduced graphene oxide10aOxygen Evolution Reaction10aoxygen reduction reaction10azirconium-substituted cobalt ferrite1 aKashyap, Varchaswal1 aKurungot, Sreekumar uhttps://library.ncl.res.in/content/zirconium-substituted-cobalt-ferrite-nanoparticle-supported-n-doped-reduced-graphene-oxide-002158nas a2200205 4500008004100000022001400041245009900055210006900154260000800223300001200231490000800243520140900251653003101660653002001691653003001711100002201741700003301763700002601796856013001822 2019 eng d a0141-813000aZebrafish acid ceramidase: expression in Pichia pastoris GS115and biochemical characterization0 aZebrafish acid ceramidase expression in Pichia pastoris GS115and cFEB a587-5930 v1223 a

Acid ceramidase (N-acylsphingosine deacylase EC 3.5.1.23; AC) catalyzes the hydrolysis of ceramide into sphingosine (SPH) and free fatty acid. Zebrafish acid ceramidase (AC) has 60% homology with the human AC). Mutations in the human AC gene asah1 are known to cause Farber disease and spinal muscular atrophy with progressive myoclonic epilepsy. Zebrafish AC was overexpressed in Pichia pastoris by inserting asah1b gene into the genome. The majority of the overexpressed enzyme was secreted into the culture medium and purified to apparent homogeneity by stepwise chromatography. The recombinant protein was glycosylated precursor, that further undergoes limited autoproteolytic processing into two subunits (alpha and beta) which are visible in SDS-PAGE. The zebrafish AC is heterodimer associated with an inter-subunit disulfide bond. SDS-PAGE estimated the mass of native enzyme to be approximately 50 kDa & size exclusion chromatography estimated the mass of the active enzyme as approximately 100 kDa, suggesting the formation of a dimer of heterodimers. The protein was secreted as a mixture of processed and unprocessed forms in the culture media. A preliminary characterization of purified zebrafish AC was done by an enzyme assay. The zebrafish AC expressed in Pichia pastoris would be used for further structural and functional analysis. (C) 2018 Elsevier B.V. All rights reserved.

10aAutoproteolytic processing10aPichia pastoris10aZebrafish acid ceramidase1 aRajput, Vijay, B.1 aKarthikeyan, Muthukumarasamy1 aRamasamy, Sureshkumar uhttps://library.ncl.res.in/content/zebrafish-acid-ceramidase-expression-pichia-pastoris-gs115and-biochemical-characterization06784nas a2200205 4500008004100000245010500041210006900146260000800215520603400223100002806257700001706285700002706302700001806329700002006347700001806367700002206385700002406407700002006431856012706451 2019 eng d00aZinc ion interactions in a two-dimensional covalent organic framework based aqueous zinc ion battery0 aZinc ion interactions in a twodimensional covalent organic frame cAUG3 a

The two-dimensional structural features of covalent organic frameworks (COFs) can promote the electrochemical storage of cations like H+, Li+, and Na+ through both faradaic and non-faradaic processes. However, the electrochemical storage of cations like Zn2+ ion is still unexplored although it bears a promising divalent charge. Herein, for the first time, we have utilized hydroquinone linked β-ketoenamine COF acting as a Zn2+ anchor in an aqueous rechargeable zinc ion battery. The charge-storage mechanism comprises of an efficient reversible interlayer interaction of Zn2+ ions with the functional moieties in the adjacent layers of COF (−182.0 kcal mol−1). Notably, due to the well-defined nanopores and structural organization, a constructed full cell, displays a discharge capacity as high as 276 mA h g−1 at a current rate of 125 mA g−1.

1 aMohammed, Abdul, Khayum1 aGhosh, Meena1 aVijayakumar, Vidyanand1 aHalder, Arjun1 aNurhuda, Maryam1 aKumar, Sushil1 aAddicoat, Matthew1 aKurungot, Sreekumar1 aBanerjee, Rahul uhttps://library.ncl.res.in/content/zinc-ion-interactions-two-dimensional-covalent-organic-framework-based-aqueous-zinc-ion02729nas a2200253 4500008004100000022001400041245018000055210006900235260000800304300001400312490000700326520183900333653001802172653001002190653001502200653000902215653001602224653001402240100002002254700002602274700002402300700002402324856012702348 2021 eng d a0971-589400aZCTs knockdown using antisense LNA GapmeR in specialized photomixotrophic cell suspensions of Catharanthus roseus: Rerouting the flux towards mono and dimeric indole alkaloids0 aZCTs knockdown using antisense LNA GapmeR in specialized photomi cJUL a1437-14530 v273 aThe present study was carried out to silence the transcription factor genes ZCT1, ZCT2 and ZCT3 via lipofectamine based antisense LNA GapmeRs transfection into the protoplasts of established photomixotrophic cell suspensions. The photomixotrophic cell suspensions with a threshold of 0.5% sucrose were raised and established using two-tiered CO2 providing flasks kept under high light intensity. The photomixotrophic cell suspensions showed morphologically different thick-walled cells under scanning electron microscopic analysis in comparison to the simple thin-walled parenchymatous control cell suspensions. The LC-MS analysis registered the vindoline production (0.0004 +/- 0.0001 mg/g dry wt.) in photomixotrophic cell suspensions which was found to be absent in control cell suspensions. The protoplasts were isolated from the photomixotrophic cell suspensions and subjected to antisense LNA GapmeRs silencing. Three lines, viz. Z1A, Z2C and Z3G were obtained where complete silencing of ZCT1, ZCT2 and ZCT3 genes, respectively, was observed. The Z3G line was found to show maximum production of vindoline (0.038 +/- 0.001 mg/g dry wt.), catharanthine (0.165 +/- 0.008 mg/g dry wt.) and vinblastine (0.0036 +/- 0.0003 mg/g dry wt.). This was supported by the multifold increment in the gene expression of TDC, SLS, STR, SGD, d4h, dat, CrT16H and Crprx. The present work indicates the master regulation of ZCT3 knockdown among all three ZCTs transcription factors in C. roseus to enhance the terpenoid indole alkaloids production. The successful silencing of transcription repressor genes has been achieved in C. roseus plant system by using photomixotrophic cell cultures through GapmeR based silencing. The present study is a step towards metabolic engineering of the TIAs pathway using protoplast transformation in C. roseus.10aCatharanthine10aLC-MS10aProtoplast10aTIAs10aVinblastine10aVindoline1 aVerma, Priyanka1 aKhan, Shamshad, Ahmad1 aParasharami, Varsha1 aMathur, Ajay, Kumar uhttps://library.ncl.res.in/content/zcts-knockdown-using-antisense-lna-gapmer-specialized-photomixotrophic-cell-suspensions02832nas a2200265 4500008004100000022001400041245012000055210006900175260000900244300001400253490000600267520190400273653002502177653001802202653001702220653003102237653003002268653002102298100002102319700002302340700003002363700001702393700002402410856013202434 2021 eng d a2574-096200aZinc-air batteries catalyzed using Co3O4 nanorod-supported N-doped entangled graphene for oxygen reduction reaction0 aZincair batteries catalyzed using Co3O4 nanorodsupported Ndoped  cMAY  a4570-45800 v43 a

The work reported here deals with the development of an efficient non-platinum electrocatalyst for electrochemical oxygen reduction reaction (ORR) through a sequential pathway involving hydrothermal treatment followed by freeze-drying to build the desired structural architecture of the catalyst. The designed catalyst (Co3O4/nitrogen-doped entangled porous 3D graphene (NEGF)), which contains Co3O4 nanorods anchored on the surface of three-dimensional (3D)-structured N-doped graphene, was found to display higher ORR activity during single-electrode testing and demonstrate a Zn-air battery (ZAB) system. Under the hydrothermal treatment at 180 degrees C, in the presence of ammonia, nitrogen was doped into the carbon framework of graphene, which subsequently formed a self-assembled entangled 3D structure of graphene after freeze-drying. The hydrothermal treatment and freeze-drying processes were found to play vital roles in tuning the morphological and structural features of the catalyst. The doped nitrogen, apart from its favorable contribution toward ORR, helped facilitate efficient dispersion of oxide nanorods on graphene. Co3O4/NEGF displayed remarkable ORR activity in 0.1 M KOH solution, as evident from the 60 mV onset potential shift compared to the state-of-the-art Pt/C catalyst and the Tafel slope value of 74 mV dec(-1) vs 68 mV dec(-1) for Pt/C. The ZAB fabricated by employing Co3O4/NEGF as the cathode catalyst was found to be an efficient competitor for the system based on the Pt/C cathode. This high performance has been credited to the controlled interplay of the governing factors such as the interfacial interactions leading to the efficient dispersion of metal oxide nanorods, increased catalyst surface area, the cooperative effect arising from the defects present in the N-doped porous 3D graphene, and the synergetic interactions operating in the system.

10acobalt-oxide nanorod10afreeze-drying10ahydrothermal10aN-doped entangled graphene10aoxygen reduction reaction10azinc-air battery1 aManna, Narugopal1 aSingh, Santosh, K.1 aKharabe, Geeta, Pandurang1 aTorris, Arun1 aKurungot, Sreekumar uhttps://library.ncl.res.in/content/zinc-air-batteries-catalyzed-using-co3o4-nanorod-supported-n-doped-entangled-graphene-oxygen01098nas a2200205 4500008004100000022001400041245006100055210006100116260000900177300001400186490000700200520047500207100002400682700002300706700001500729700001700744700002400761700001900785856008800804 2023 eng d a1359-734500aZwitterionic disilanylium from an unsymmetrical disilene0 aZwitterionic disilanylium from an unsymmetrical disilene cFEB  a1669-16720 v593 a

The reaction of PhC(NtBu)2SiSi(SiMe3)(3) (1) with Me3SiCH(2)Cl afforded an unsymmetrical sp(2)-sp(3) disilene, 2, with concomitant elimination of Me3SiCl. The analogous reaction with PhC(NtBu)2SiCl resulted in the oxidative addition of the C-Cl bond at the Si(II) atom (3). The reactions of 2 with sulfur and selenium led to compounds with Si=E (E=S (4) and Se (5)) double bonds. Tellurium reacted differently with 2 and furnished a zwitterionic compound, 6.

1 aBisai, Milan, Kumar1 aAjithkumar, V., S.1 aRaj, Vipin1 aVanka, Kumar1 aGonnade, Rajesh, G.1 aSen, Sakya, S. uhttps://library.ncl.res.in/content/zwitterionic-disilanylium-unsymmetrical-disilene01905nas a2200289 4500008004100000022001400041245004600055210004400101260000900145490000700154520110600161653001801267653001401285653001501299653001701314653001501331100001901346700001801365700002001383700002501403700002401428700001701452700002401469700002101493700002201514856007901536 2023 eng d a1434-194800aZwitterionic tetrastanna(II) cyclic crown0 aZwitterionic tetrastannaII cyclic crown cOCT 0 v263 a

A 12-membered zwitterionic tetrastanna(II) cycle 1 having a crown ether-like topology has been isolated from the deprotonation of 1,1 & PRIME;-methylenediimidazole (B) with two equivalents of Sn[N(SiMe3)(2)](2) (A). The solid-state structure and NMR analysis confirms the tetrastanna(II) cycle 1 to be comprised of two stannate(II) and two stannyliumylidene ion pairs in alternating positions of the heterocycle. Computational analysis shows greater nucleophilicity at the proximally located stannate(II) centers. Nonetheless, the tetrastanna(II) cycle 1 remains poorly reactive due to engagement of Sn-II lone pair electrons in intramolecular donor-acceptor interactions. Simple deprotonation reaction between Sn[N(SiMe3)(2)](2) (A) and N-(diisopropylphenyl)imidazole (C) in equimolar ratio has led to a stannylene 2, involving the formation of a Sn-C covalent bond with the anionic imidazol-2-yl carbon center along with the release of NH(SiMe3)(2). Compound 2 exists as a dimer, where the unsubstituted ring nitrogen atom coordinated intermolecularly to the other stannylene center.

10aDeprotonation10aImidazole10aMacrocycle10aSn-II cation10astannylene1 aSahoo, Padmini1 aChibde, Purva1 aDas, Satyabrata1 aBanerjee, Subhrashis1 aMali, Bhupendra, P.1 aVanka, Kumar1 aGonnade, Rajesh, G.1 aYildiz, Cem., B.1 aMajumdar, Moumita uhttps://library.ncl.res.in/content/zwitterionic-tetrastannaii-cyclic-crown02194nas a2200265 4500008004100000022001400041245011500055210006900170260000800239300001400247490000800261520130100269653001001570653001801580653002501598653002101623653000901644100002101653700002501674700002301699700002401722700002901746700002301775856013001798 2024 eng d a1011-372X00aZrO2 supported Cu nanoparticles for sonogashira and ullmann coupling reactions under palladium-free conditions0 aZrO2 supported Cu nanoparticles for sonogashira and ullmann coup cJUN a3078-30900 v1543 a

Cu nanoparticles supported on ZrO2 (CuNPs@ZrO2) were synthesized using a one-step co-precipitation process, and their application in C-C coupling reactions was investigated. The catalyst was characterized using XRD, XPS, SEM, TEM, and TGA techniques. The prepared catalyst was used for the Sonogashira cross-coupling reactions of aryl bromides with phenyl-acetylene in the presence of K2CO3 in DMF at 110 degrees C, which resulted in substituted alkynes with good to excellent yields. The protocol was also extended for the Ullmann coupling reactions of aryl iodides under similar reaction conditions, yielding the desired products with good to excellent yields without homo-coupling. Interestingly, unlike other copper catalysts, the present catalyst worked under air and did not require an inert atmosphere to prevent alkyne. This catalytic system is versatile, tolerant, and significantly cheaper than the ``traditional'' Pd-catalyzed Sonogashira cross-coupling of terminal alkynes with aryl halides. The catalyst could be reused for five catalytic cycles with no significant change in the product yield. All of these characteristics make our prepared CuNPs@ZrO2 catalyst quite suitable for the gram-scale synthesis of biaryls and alkynes, with a simple workup.{GRAPHIACAL ABSTRACT

10aCuNPs10aRecyclability10aSonogashira coupling10aUllmann coupling10aZrO21 aPatil, Seema, P.1 aRajmane, Archana, S.1 aJadhav, Sanjay, N.1 aRajmane, Vijaya, S.1 aRode, Chandrashekhar, V.1 aKumbhar, Arjun, S. uhttps://library.ncl.res.in/content/zro2-supported-cu-nanoparticles-sonogashira-and-ullmann-coupling-reactions-under-palladium02305nas a2200349 4500008004100000022001400041245011900055210006900174260000900243490000700252520118800259653000901447653002301456653001301479653002601492653002001518100001701538700002201555700002201577700001901599700001801618700001801636700002801654700002401682700002101706700002001727700002001747700001701767700002501784700001801809856012801827 2025 eng d a1613-681000aZincke-derived viologen covalent organic framework as a high-performance cathode for aqueous zinc-iodine batteries0 aZinckederived viologen covalent organic framework as a highperfo cDEC 0 v213 a

Aqueous zinc-iodine (Zn-I2) batteries are among the most promising energy storage technologies, offering high energy density, low cost, and intrinsic safety. However, their practical deployment is hindered by the polyiodide shuttle effect, leading to rapid capacity fading and poor cycling performance. This work demonstrates the application of a crystalline viologen-based covalent organic framework (TAB-DNP-BP COF), synthesized via a one-pot Zincke reaction, as an efficient iodine host material. The cationic backbone of the TAB-DNP-BP COF effectively confines iodine (I2) species and electrostatically traps polyiodides, suppressing their migration and protecting the zinc anode. Zinc-iodine batteries assembled with an I2-enriched TAB-DNP-BP COF (TAB-DNP-BP COF@I2) cathode deliver a high specific capacity of 337 mAh g-1 at 0.5 C, surpassing the performance of most reported COF-, MOF-, and cage-based systems, while exhibiting excellent cycling stability over 5000 cycles. This work highlights the potential of ionic COFs for stabilizing iodine chemistry and offers a promising strategy toward the development of high-performance, durable aqueous Zn-I2 batteries.

10aiCOF10aiodine confinement10aviologen10azinc-iodine batteries10aZincke reaction1 aDas, Gobinda1 aShivade, Rajkiran1 aPandey, Priyanshi1 aVarghese, Sabu1 aRajput, Nitul1 aMatouk, Zineb1 aMartinez, Jose, Ignacio1 aStraubinger, Rainer1 aBenyettou, Farah1 aGandara, Felipe1 aOlson, Mark, A.1 aAouad, Samer1 aShelke, Manjusha, V.1 aTrabolsi, Ali uhttps://library.ncl.res.in/content/zincke-derived-viologen-covalent-organic-framework-high-performance-cathode-aqueous-zinc01174nas a2200217 4500008004100000022001400041245016400055210006900219260000800288490000700296520037700303100002100680700002100701700001700722700002100739700001700760700001700777700002100794700002000815856012100835 2025 eng d a1359-734500aZn(ii)-metallo-photoantibiotics: experimental and computational approach identifying a therapeutic role for antibacterial and antibiofilm applications0 aZnsciiscmetallophotoantibiotics experimental and computational a cJUL0 v613 a

The antibacterial profiles of curcumin-based novel Zn(ii)-metallo-photoantibiotics against E. coli and B. subtilis are reported. In silico studies indicated their ROS generation capacity and binding interaction with bacterial proteins. Therapeutic results indicated the advantages of these Zn(ii)-metallo-photoantibiotics in antibacterial photodynamic therapy.

1 aKushwaha, Rajesh1 aKumari, Sangeeta1 aMishra, Arya1 aUpadhyay, Anjali1 aRai, Archana1 aNayak, Malay1 aMukherjee, Sudip1 aBanerjee, Samya uhttps://library.ncl.res.in/content/znii-metallo-photoantibiotics-experimental-and-computational-approach-identifying