01793nas a2200253   4500008004100000022001400041245014200055210006900197260007300266300001000339490000800349520087900357653001301236653001801249653002301267653002201290653002101312653001801333100001801351700001601369700001701385700001701402856012001419       2015                        eng d  a0167-577X00aFacile biological approach for immobilization, physicochemical characterization and antibacterial activity of noble metals nanocomposites0 aFacile biological approach for immobilization physicochemical ch  aPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSbELSEVIER SCIENCE BVcJUN  a86-900 v1483 a<p>The use of biopolymer as template to regulate metallic nanoparticles is promising field in green nanotechnology. We have designed a facile biological way for rapid synthesis and immobilization of gold and silver nanoparticles on alginate films using leaf extract of Cassia auriculata. The prepared gold bio-nanocomposite (Au-BNC) and silver bio-nanocomposite (Ag-BNC) were characterized by UV-vis spectroscopy, Fourier transform infrared spectroscopy, Transmission electron microscopy and Thermal analysis. The bio-nanocomposites exhibited good antibacterial activity against both gram positive (Bacillus subtilis) and gram negative (Escherichia coli) bacteria. The metal nanoparticle embedded films have number of applications in catalysis, optical biosensors, electronic, biomedical devices and environmental remediation. (C) 2015 Elsevier B.V. All rights reserved.</p>10aAlginate10aAntibacterial10aBio-nanocomposites10aCassia auriculata10aCharacterization10aNanoparticles1 aParveen, Asra1 aAli, Tayyab1 aWahid, Malik1 aRao, Srinath  uhttps://library.ncl.res.in/content/facile-biological-approach-immobilization-physicochemical-characterization-and-004223nas a2200277   4500008004100000022001400041245011700055210006900172260000800241300000700249490000700256520327800263653002603541653002303567653002603590653002103616653001303637100002103650700002303671700002203694700002603716700002403742700002403766700002803790856012703818       2023                        eng d  a1868-695800aGreen adeptness in synthesis of non-toxic copper and cobalt oxide nanocomposites with multifaceted bioactivities0 aGreen adeptness in synthesis of nontoxic copper and cobalt oxide  cDEC  a790 v143 a<p>
	Background: In the present era, we are facing different health problems mainly concerning with drug resistance in microorganisms as well as in cancer cells. In addition, we are also facing the problems of controlling oxidative stress and insect originated diseases like dengue, malaria, chikungunya, etc. originated from mosquitoes. In this investigation, we unfurled the potential of Achatina fulica mucus in green synthesis of mucus mediated copper oxide bio-nanocomposites (SM-CuONC) and cobalt oxide bio-nanocomposites (SM-Co3O4NC). Herein we carried out the physico-chemical characterization like UV-Vis spectra, X-ray diffraction (XRD), Field Emission Scanning Electron Microscopy (FESEM), Transmission electron microscopy (TEM), Energy Dispersive X-ray Analysis (EDAX) and X-ray photoelectron spectroscopy (XPS) of as synthesized bio-nanocomposites. Both the bio-nanocomposites were tested for their potential as antimicrobial activity using well diffusion assay, anticancer activity by MTT assay, antioxidant activity by phosphomolybdenum assay and mosquito larvicidal activity.Results: The results of this study revealed that, SM-CuONC and SM-Co3O4NC were synthesized successfully using A. fulica mucus. The FESEM and TEM data reveal the formation of nanoparticles with quasi-spherical morphology and average particle size of similar to 18 nm for both nanocomposites. The EDAX peak confirms the presence of elemental copper and cobalt in the analyzed samples. The X-ray diffraction analysis confirmed the crystalline nature of the CuO and Co3O4. The result of anti microbial study exhibited that, SM-CuONC showed maximum antimicrobial activity against Escherichia coli NCIM 2065 and Aspergillus fumigatus NCIM 902 which were noted as 2.36 +/- 0.31 and 2.36 +/- 0.59 cm resp. at 60 mu g/well concentration. The result of anticancer activity for SM-CuONC was exhibited as, 68.66 +/- 3.72, 62.66 +/- 3.61 and 71.00 +/- 2.36 percent kill, while SM-Co3O4NC exhibited 61.00 +/- 3.57, 72.66 +/- 4.50 and 71.66 +/- 4.22 percent kill against Human colon cancer (HCT-15), Cervical cancer (HeLa), and Breast cancer (MDA-MB-231) cell lines, respectively, at 20 mu g/well concentration. Both the nanocomposites also exhibited better antioxidant activity. Total antioxidant activity for SM-CuONC at 50 mu g/ml concentration was found to be highest as 55.33 +/- 3.72 while that of SM-Co(3)O(4)Ns was 52.00 +/- 3.22 mM of ascorbic acid/mu g respectively. Both bio-nanocomposites also exhibited 100% mosquito larvicidal activity at concentration ranging from 40 to 50 mg/l. During cytotoxicity study it is noted that at 5 mu g/well concentration, SM-CuO and SM-Co3O4NCs suspension showed more than 97% viability of normal (L929) cell lines. We also studied phytotoxicity of both bio-nanocomposites on Triticum aestivum. In this study, 100% seed germination was observed when seeds are treated with SM-CuONC and SM-Co3O4NC at 500 mg/l and 250 mg/l concentration respectively.Conclusions: This study concludes that in future as synthesized SM-CuONC and SM-Co3O4NC can be used in pharmaceutical, health care system for betterment and welfare of human life as both bio-nanocomposites exhibits better antimicrobial, anticancer, antioxidant and mosquito larvicidal potential.</p>
10aAchatina fulica mucus10aBio-nanocomposites10aBiological activities10aCharacterization10aToxicity1 aMane, Pramod, C.1 aKadam, Deepali, D.1 aKhadse, Ashok, N.1 aChaudhari, Aditya, R.1 aUghade, Supriya, P.1 aAgawane, Sachin, B.1 aChaudhari, Ravindra, D.  uhttps://library.ncl.res.in/content/green-adeptness-synthesis-non-toxic-copper-and-cobalt-oxide-nanocomposites-multifaceted