01179nas a2200217   4500008004100000022001400041245013200055210006900187260010600256300001200362490000700374520028700381653001500668653002500683653002400708653002500732653003100757100001900788700002800807856012600835       2008                        eng d  a0040-403900a[2+2+2]-cyclotrimerization approach for the synthesis of enantiopure isochromans using a carbohydrate derived dialkyne template0 a222cyclotrimerization approach for the synthesis of enantiopure   aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcJAN  a445-4480 v493 a<p>An easy access to enantiopure isochromans through cross alkyne trimerization of a glucose derived dialkyne was developed. One of the synthesized isochromans was converted into a novel tricyclic nucleoside by simple transformations. (C) 2007 Elsevier Ltd. All rights reserved.</p>10aisochroman10atricyclic nucleoside10aVorbruggen reaction10aWilkinson's catalyst10a[2+2+2]-Cyclotrimerization1 aRamana, C., V.1 aSuryawanshi, Sharad, B.  uhttps://library.ncl.res.in/content/222-cyclotrimerization-approach-synthesis-enantiopure-isochromans-using-carbohydrate-001557nas a2200241   4500008004100000022001400041245015700055210006900212260010600281300001400387490000700401520056300408653002500971653002500996653002501021653002401046653003101070100002801101700002501129700002401154700001901178856011801197       2010                        eng d  a0040-402000aIsochroman- and 1,3-dihydroisobenzofuran-annulation on carbohydrate templates via [2+2+2]-cyclotrimerization and synthesis of some tricyclic nucleosides0 aIsochroman and 13dihydroisobenzofuranannulation on carbohydrate   aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcAUG  a6085-60960 v663 a<p>The synthesis of enantiopure tricyclic systems comprising isochroman or dihydroisobenzofuran units integrated with sugar templates has been documented. The alkyne cylotrimerization reaction has been employed with easily accessible sugar diynes for the key bicyclic ring construction and thus a provision to alter the functional groups on the newly formed aromatic rings. By selecting two representative trimerization products, we have synthesized the tricyclic nucleosides by simple synthetic manipulations. (c) 2010 Elsevier Ltd. All rights reserved.</p>10aDihydroisobenzofuran10aDihydroisobenzopyran10aModified nucleosides10aVorbruggen reaction10a[2+2+2] cyclotrimerization1 aSuryawanshi, Sharad, B.1 aDushing, Mangesh, P.1 aGonnade, Rajesh, G.1 aRamana, C., V.  uhttps://library.ncl.res.in/content/isochroman-and-13-dihydroisobenzofuran-annulation-carbohydrate-templates-222-0