01322nas a2200217 4500008004100000022001400041245009700055210006900152260010600221300001200327490000800339520049000347653002700837653002400864653001700888100001600905700001900921700001700940700002500957856012200982 2007 eng d a0038-109800aDirect comparison of the aging and memory effects of magnetic nanoclusters and nanoparticles0 aDirect comparison of the aging and memory effects of magnetic na aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcFEB a307-3100 v1413 a

The magnetic characteristics of a dense magnetic nanoparticle system and a spin glass system consisting of magnetic nanoclusters are compared. Zero field cooled and field cooled magnetization measurements, including aging and memory experiments, of the nanoparticle and the magnetic cluster systems show similar characteristics, suggesting a common origin for the spin glass-type behavior of the magnetic nanoparticle and nanocluster systems. (C) 2006 Published by Elsevier Ltd.

10aMagnetic nanoparticles10amagnetic properties10aspin glasses1 aSankar, Raj1 aVijayanand, S.1 aVerma, Seema1 aJoy, Pattayil, Alias uhttps://library.ncl.res.in/content/direct-comparison-aging-and-memory-effects-magnetic-nanoclusters-and-nanoparticles01634nas a2200205 4500008004100000022001400041245020900055210006900264260007500333300001200408520071500420653002701135653002401162653001701186100002601203700002401229700002601253700001901279856013001298 2007 eng d a0936-521400aReactions of o-aminothiophenol and o-aminophenyl disulfide with itaconic anhydride and (-)-dimenthyl itaconate: access to enantiomerically pure 1,5-benzothiazepines and benzothiazolyl-2-methylacrylic acid0 aReactions of oaminothiophenol and oaminophenyl disulfide with it aRUDIGERSTR 14, D-70469 STUTTGART, GERMANYbGEORG THIEME VERLAG KGcFEB a457-4633 a

{A facile chemo- and regioselective reactions of o-aminothiophenol (o-ATP) with itaconic anhydride is described. 1,5-Benzothiazepinyl-3-acetic acid is obtained in 81% yield via the exclusive Michael type addition of the thiol unit from o-ATP to the carbon-carbon double bond in itaconic anhydride followed by an intramolecular anhydride ring opening with an amine unit. The moderately stereoselective Michael type addition of the thiol unit from o-ATP to (-)-dimenthyl itaconate to obtain a mixture of diastereomers in a 7:3 ratio in 82% yield has been demonstrated. The reductive sulfur-sulfur bond cleavage in the dicarboxylic acid, 2({2-[2-(3-carboxybut-3-enoylamino)phenyidisulfanyl]phenylcarbamoyl\

10aMagnetic nanoparticles10amagnetic properties10aspin glasses1 aBaag, Md., Merajuddin1 aSahoo, Manoj, Kumar1 aPuranik, Vedavati, G.1 aArgade, N., P. uhttps://library.ncl.res.in/content/reactions-o-aminothiophenol-and-o-aminophenyl-disulfide-itaconic-anhydride-and-dimenthyl-002267nas a2200265 4500008004100000022001400041245011100055210006900166260007300235300001200308490000600320520129400326653001701620653001801637653002601655653002701681100002301708700002101731700001701752700002501769700002701794700002201821700002901843856012901872 2012 eng d a1549-963400aCharacterization of biocompatible NiCo2O4 nanoparticles for applications in hyperthermia and drug delivery0 aCharacterization of biocompatible NiCo2O4 nanoparticles for appl aPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSbELSEVIER SCIENCE BVcMAY a452-4590 v83 a

Monodispersed, superparamagnetic nickel cobaltite (NCO) nanoparticles were functionalized using mercaptopropionic acid (MPA). MPA conjugates with NCO forming a metal-carboxylate linkage, with the MPA-MPA interaction occurring via formation of disulfide bonds, leaving another carboxyl end free for additional conjugation. The cytotoxicity studies on NCO-MPA show cell viability of similar to 100% up to a dosage of 40 mu g/mL on SiHa, MCF7, and B16F10 cell lines, and on mouse primary fibroblasts. Time-dependent cell viability studies done for a duration of 72 hours showed the cell lines' viability up to 80% for dosages as high as 80 mu g/mL. Negligible leaching (<5 ppm) of ionic Co or Ni was noted into the delivery medium. Upon subjecting the NCO-MPA dispersion (0.1 mg/mL) to radiofrequency absorption, the nanoparticles were heated to 75 degrees C within 2 minutes, suggesting its promise as a magnetic hyperthermia agent. Furthermore, the amino acid lysine and the drug cephalexin were successfully adducted to the NCO system, suggesting its potential for drug delivery. From the Clinical Editor: NCO-MPA nanopartciles were found to be promising magnetic hyperthermia agents, suggesting potential future clinical applications. (C) 2012 Elsevier Inc. All rights reserved.

10aCytotoxicity10adrug delivery10aMagnetic hyperthermia10aMagnetic nanoparticles1 aKale, Sangeeta, N.1 aJadhav, Anil, D.1 aVerma, Seema1 aKoppikar, Soumya, J.1 aKaul-Ghanekar, Ruchika1 aDhole, Sanjay, D.1 aOgale, Satishchandra, B. uhttps://library.ncl.res.in/content/characterization-biocompatible-nico2o4-nanoparticles-applications-hyperthermia-and-drug-002492nas a2200277 4500008004100000022001400041245016500055210006900220260000800289300001100297490000800308520149600316653001801812653001201830653001801842653002701860100002101887700002701908700002301935700002501958700002701983700002302010700003102033700002602064856012402090 2020 eng d a1381-514800aEpoxy functionalized polymer grafted magnetic nanoparticles by facile surface initiated polymerization for immobilization studies of Candida Antarctica lipase B0 aEpoxy functionalized polymer grafted magnetic nanoparticles by f cFEB a1044540 v1473 a

Immobilization of Candida Antarctica lipase B (Cal-B) was done on the epoxy functionalized polymer (EFP) grafted magnetic nanoparticles (MNPs) via covalent attachment with the active epoxy groups. The EFP brushes were grafted on iron-oxide based MNPs by a facile surface-initiated atom transfer radical polymerization (ATRP) using activators generated by electron transfer (AGET) of glycidyl methacrylate (GMA). Each step of the surface modification, polymer grafting, and enzyme immobilization process on the polymer grafted MNPs was studied using Fourier transform infrared spectroscopy (FTIR). A thermogravimetric analysis (TGA) calculated the amount of engineered organic components, a transmission electron microscopy (TEM) visualized the core-shell formation of the MNPs, and a vibrating sample magnetometer (VSM) validated their magnetic properties at various modification stages. The lipase immobilization efficiency was described as a function of immobilization time, as well as, enzyme amount. The activity was characterized within a range of pH, temperature, kinetic parameters, resusability and storage stability, for both the free and immoblized Cal-B enzyme. The results of this study suggested that poly(GMA) grafted MNPs can be successfully used for the immobilization of Cal-B with improved efficiencies compared to those obtained with free soluble lipase. The reported enzyme immobilization method appears to be reproducible and scalable for industrial production.

10aCal-B enzymes10aenzymes10aImmoblization10aMagnetic nanoparticles1 aAfzal, Haq, Asif1 aGhorpade, Ravindra, V.1 aThorve, Asmita, K.1 aNagaraja, Sreeharsha1 aAl-Dhubiab, Bandar, E.1 aMeravanige, Girish1 aRasool, Sahibzada, Tasleem1 aRoopashree, Teeka, S. uhttps://library.ncl.res.in/content/epoxy-functionalized-polymer-grafted-magnetic-nanoparticles-facile-surface-initiated01782nas a2200277 4500008004100000022001400041245011400055210006900169260000800238300001000246490000700256520088900263653001801152653000901170653002101179653001001200653002901210653002701239653001501266653001601281100001701297700001801314700002001332700002701352856012501379 2020 eng d a0019-559600aMagnetic and luminescent multifunctional nanohybrid: Fe3O4@CaF2:Tb3+: a facile synthesis and characterization0 aMagnetic and luminescent multifunctional nanohybrid Fe3O4CaF2Tb3 cJAN a31-350 v583 a

In the present study, bi-functional hybrid nanomaterial has been synthesized and characterized via facile method and characterized. The synthesized nanomaterial shows both magnetic and luminescent properties which are confirmed by VSM (vibrating sample magnetometer), UV-Vis spectra and the photoluminescence emission spectra. For the magnetic phase, i.e., nanocrystalline magnetite, Fe3O4 is used as the core which is then functionalized using polyethylene glycol (PEG) and for the luminescent phase, polyethylenimine (PEI) functionalized CaF2 doped with Tb3+ is used as the emitter. Wherein, both PEG and PEI serve the dual purpose of functionalization as well as stabilization by steric repulsion. The structure and morphology of the synthesized bifunctional hybrid nanomaterial are studied with the help of scanning electron microscopy (SEM) and X-ray powder diffraction.

10aBiocompatible10aCaF210aCo-precipitation10aFe3O410aLuminescent nanoparticle10aMagnetic nanoparticles10aNanohybrid10aTb3+ doping1 aVats, Monika1 aKumar, Rakesh1 aSharma, Jyotsna1 aLuwang, Meitram, Niraj uhttps://library.ncl.res.in/content/magnetic-and-luminescent-multifunctional-nanohybrid-fe3o4caf2tb3-facile-synthesis-and02461nas a2200253 4500008004100000022001400041245009800055210006900153260000800222300001100230490000700241520162000248653001901868653001701887653002001904653002701924653001501951653001701966100002901983700002102012700001702033700003402050856012302084 2022 eng d a1773-224700aBlend of neem oil based polyesteramide as magnetic nanofiber mat for efficient cancer therapy0 aBlend of neem oil based polyesteramide as magnetic nanofiber mat cSEP a1036290 v753 a

Stearic acid-coated magnetic nanoparticles (SMN) and FU (5-Fluorouracil) were immobilized in the blends of neem oil-based polyesteramide and fabricated as nanofiber mat (NM) for controlled release of FU under the influence of an external magnetic field for targeted drug delivery to treat cancer efficiently. Analyzed the surface morphology of the fibers using E-SEM, it was observed that the fibers were smooth with the diameter ranging from 250 to 450 nm. TEM studies showed the uniform distribution of SMN in the nanofibers. The physico-chemical properties of NM and raw materials were analyzed using FTIR, TGA, and XRD. The results suggested that the polymers were well blended. In-vitro FU release studies of the NMs recorded a significant difference in the cumulative percentage of FU release from SMN-NMs. The SMN-NMs released 95% of FU in 4 h, whereas, NMs released 83% of FU in 24 h. The cell viability assay for the NM was evaluated in the L929 mouse fibroblast cells, where >75% of cells were viable. The hemolysis assay for the developed SMN-NF showed <5% of hemolysis, which indicated the NMs were safe for application. The anti-cancer activity of FU loaded SMN-NF was analyzed in the MCF-7 cancer cell line, which recorded more than 50% cell death within 24 h. From SQUID analysis, we found that the 10% SMN were superparamagnetic in nature, the magnetization at 30 kOe was observed to be 4.3 emu/g. Based on the in vitro results, we concluded that the developed SMN-NMs are recommended for in vivo studies to understand their efficacy for the targeted drug delivery to treat cancer.

10a5-Fluorouracil10adrug release10aelectrospinning10aMagnetic nanoparticles10ananofibers10aStearic acid1 aPatel, Pratikshkumar, R.1 aSingam, Amarnath1 aDadwal, Arun1 aGundloori, Rathna, Venkata Na uhttps://library.ncl.res.in/content/blend-neem-oil-based-polyesteramide-magnetic-nanofiber-mat-efficient-cancer-therapy