02744nas a2200265 4500008004100000022001400041245012400055210006900179260007300248300001200321490000800333520176200341653001002103653001102113653003802124653002902162653002002191653001902211653003002230100001902260700002102279700001902300700002802319856013102347 2006 eng d a1381-116900aChemoselective anti-Markovnikov hydroamination of alpha,beta-ethylenic compounds with amines using montmorillonite clay0 aChemoselective antiMarkovnikov hydroamination of alphabetaethyle aPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSbELSEVIER SCIENCE BVcMAY a210-2170 v2503 a

The catalytic activity of montmorillonite clays as a catalyst for the hydroamination of alpha,beta-ethylenic compounds with amines was tested. Aniline and substituted amines reacted with alpha,beta-ethylenic compounds in the presence of catalytic amount of commercially available clay to afford exclusively anti-Markovnikov adduct in excellent yields. Aniline reacted with ethyl acrylate to yield only anti-Markovnikov adduct N-[2-(ethoxycarbonyl)ethyl] aniline (mono-addition product). No Markovnikov adduct (N-[1-(ethoxycarbonyl)ethyl]aniline and double addition product N,N-bis[2-(ethoxycarbonyl)ethyl]aniline were formed under selected reaction conditions. For a better exploitation of the catalytic activity in terms of increased activity and improved selectivity for the mono-addition product, the reaction parameters were optimized in terms of temperature, solvent, reactant mole ratio. Under optimized reaction conditions, montmorillonite clay K-10 showed a superior catalytic performance in the hydroamination of ethyl acrylate with aniline with a conversion of aniline to mono-addition product (almost 100% chemoselectivity) with a high rate constant 0.3414 min(-1) compared to the reported protocols. The dependence of conversion of aniline over different types of montmorillonite clays (K-10, K-20, K-30, Al-Pillared clay and untreated clay) has also been discussed. The activities of clay for the hydroamination of different aromatic and aliphatic amines have also been investigated. Under harsh reaction conditions (increased temperature and long reaction time) small amounts of di-addition products were observed. The kinetics data has been interpreted using the initial rate approach model. (c) 2006 Elsevier B.V. All rights reserved.

10aalpha10aamines10aanti-Markovnikov addition product10abeta-ethylenic compounds10achemo-selective10ahydroamination10aK-10 montmorillonite clay1 aJoseph, Trissa1 aShanbhag, G., V.1 aSawant, D., P.1 aHalligudi, Shivappa, B. uhttps://library.ncl.res.in/content/chemoselective-anti-markovnikov-hydroamination-alphabeta-ethylenic-compounds-amines-using-101037nas a2200253 4500008004100000022001400041245006800055210006500123260007300188300001000261490000600271520019600277653001100473653001700484653002300501653002700524653001600551100002200567700002200589700002300611700002500634700002700659856009700686 2007 eng d a1566-736700aEfficient N-arylation of amines catalyzed by Cu-Fe-hydrotalcite0 aEfficient Narylation of amines catalyzed by CuFehydrotalcite aPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSbELSEVIER SCIENCE BVcJAN a65-680 v83 a

An efficient N-arylation of amines with aryl halides in presence of heterogeneous recyclable Cu-Fe-hydrotalcite catalyst has been developed. (c) 2006 Elsevier B.V. All rights reserved.

10aamines10aAryl halides10aCu-Fe-hydrotalcite10aheterogeneous catalyst10aN-arylation1 aJadhav, Vinod, H.1 aDumbre, Deepa, K.1 aPhapale, Vilas, B.1 aBorate, Hanumant, B.1 aWakharkar, Radhika, D. uhttps://library.ncl.res.in/content/efficient-n-arylation-amines-catalyzed-cu-fe-hydrotalcite01433nas a2200217 4500008004100000022001400041245010200055210006900157260007500226300001200301520059500313653001400908653002000922653002900942653001100971653003300982653002201015100002801037700001901065856013101084 2007 eng d a0936-521400aEfficient one-pot synthesis of alpha-amino phosphonates catalyzed by bismuth nitrate pentahydrate0 aEfficient onepot synthesis of alphaamino phosphonates catalyzed  aRUDIGERSTR 14, D-70469 STUTTGART, GERMANYbGEORG THIEME VERLAG KGcMAR a745-7483 a

A simple, efficient, and environmentally benign method has been developed for the synthesis of alpha-amino phosphonates through a one-pot reaction of aldehydes with amines and diethyl phosphite in the presence of bismuth nitrate pentahydrate as a catalyst. Some of the major advantages of this protocol are: good yields, the involvement of a less-expensive and non-toxic catalyst, mild and solvent-free reaction conditions and also tolerance towards other functional groups present in the substrates. Eighteen examples are described, highlighting the substrate scope of the reaction.

10aaldehydes10aalkyl phosphite10aalpha-amino phosphonates10aamines10abismuth nitrate pentahydrate10asynthetic methods1 aBhattacharya, Asish, K.1 aKaur, Tanpreet uhttps://library.ncl.res.in/content/efficient-one-pot-synthesis-alpha-amino-phosphonates-catalyzed-bismuth-nitrate-pentahydrate01479nas a2200229 4500008004100000022001400041245009600055210006900151260010600220300001400326490000700340520059400347653001400941653002000955653002900975653001101004653002301015653002901038100002801067700002701095856012701122 2008 eng d a0040-403900aAmberlite-IR 120 catalyzed three-component synthesis of alpha-amino phosphonates in one-pot0 aAmberliteIR 120 catalyzed threecomponent synthesis of alphaamino aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcAPR a2598-26010 v493 a

A simple, efficient, and environmentally benign method for a three-component reaction of an amine, an aldehyde or a ketone, and diethyl phosphite catalyzed by Amberlite-IR 120 resin has been developed to afford alpha-amino phosphonates in high yields and short reaction times under solvent-free reaction conditions. The major advantages of the present method are good yields, inexpensive, ecofriendly and reusable catalyst, mild and solvent-free reaction conditions and tolerance towards various functionalities present in the substrates. (c) 2008 Elsevier Ltd. All rights reserved.

10aaldehydes10aalkyl phosphite10aalpha-amino phosphonates10aamines10aion-exchange resin10amulti-component reaction1 aBhattacharya, Asish, K.1 aRana, Kalpeshkumar, C. uhttps://library.ncl.res.in/content/amberlite-ir-120-catalyzed-three-component-synthesis-alpha-amino-phosphonates-one-pot-002048nas a2200265 4500008004100000022001400041245010000055210006900155260007300224300001000297490000800307520110900315653001101424653002301435653002401458653002501482653002801507100001901535700002101554700001501575700002101590700001701611700002801628856012601656 2008 eng d a1381-116900aNon-phosgene route for the synthesis of methyl phenyl carbamate using ordered AISBA-15 catalyst0 aNonphosgene route for the synthesis of methyl phenyl carbamate u aPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSbELSEVIER SCIENCE BVcNOV a29-330 v2953 a

Methyl phenyl carbamate (MPC) has been synthesized Under liquid phase conditions from dimethyl carbonate and aniline by using mesoporous AISBA-15 catalyst. The catalyst with different Si/Al ratio was synthesized by isomorphous Substitution of aluminium into the framework of siliceous SBA-15. The structural integrity of the catalyst system was diagnosed with the help of various characterization techniques Such as X-ray diffraction, Surface analysis, and the acidity measurement has been done by TPD using ammonia as probe molecule. AISBA-15 (Si/Al = 10) exhibited highest catalytic activity in the synthesis of MPC under the reaction Conditions Studied. The effect of parameters Such as molar ratio of reactants, catalyst concentration. reaction temperature and time on the conversion of aniline was investigated. The results demonstrated that an aniline conversion of 99% and MPC selectivity of 71% were achieved when the reaction was carried out at 100 C, DMC to aniline mole ratio of 10 with 5% of catalyst (wt% of total reaction mixture) for 3 h. (c) 2008 Elsevier B.V. All rights reserved.

10aamines10aDimethyl carbonate10aMesoporous AISBA-1510aMethoxycarbonylation10aMethyl phenyl carbamate1 aLucas, Nishita1 aAmrute, Amol, P.1 aPalraj, K.1 aShanbhag, G., V.1 aVinu, Ajayan1 aHalligudi, Shivaraj, B. uhttps://library.ncl.res.in/content/non-phosgene-route-synthesis-methyl-phenyl-carbamate-using-ordered-aisba-15-catalyst-001309nas a2200217 4500008004100000022001400041245014200055210006900197260007500266300001200341520047000353653001300823653001100836653001400847653001100861653001500872100002200887700002800909700002200937856013200959 2009 eng d a0039-788100aCobalt(II) chloride hexahydrate-diisopropylamine catalyzed mild and chemoselective reduction of carboxylic esters with sodium borohydride0 aCobaltII chloride hexahydratediisopropylamine catalyzed mild and aRUDIGERSTR 14, D-70469 STUTTGART, GERMANYbGEORG THIEME VERLAG KGcFEB a660-6643 a

The cobalt-catalyzed reduction of unsaturated alpha-cyano carboxylic esters using sodium borohydride (NaBH(4)) leads to the corresponding saturated cyano alcohols in high yields. In particular, the new catalytic system cobalt(II) chloride-diisopropylamine in combination with NaBH(4) showed excellent activity in the chemoselective reduction of a variety of carboxylic esters to their corresponding alcohols in good to excellent yields under mild conditions.

10aAlcohols10aamines10acatalysis10aEsters10areductions1 aJagdale, Arun, R.1 aParaskar, Abhimanyu, S.1 aSudalai, Arumugam uhttps://library.ncl.res.in/content/cobaltii-chloride-hexahydrate-diisopropylamine-catalyzed-mild-and-chemoselective-reduction-001602nas a2200217 4500008004100000022001400041245014100055210006900196260007300265300001400338490000700352520071200359653001901071653001101090653004001101653002601141653004001167100002601207700002201233856012901255 2011 eng d a1566-736700aThermally decomposed Ni-Fe-hydrotalcite: a highly active catalyst for the solvent-free N-acylation of different amines by acid chlorides0 aThermally decomposed NiFehydrotalcite a highly active catalyst f aPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSbELSEVIER SCIENCE BVcAUG a1351-13560 v123 a

A composite Ni-Fe catalyst obtained from the thermal decomposition of Ni-Fe-hydrotalcite at 600 degrees C shows very high activity in the solvent-free N-acylation of amines by different acid chlorides with high product yields under very mild reaction conditions (viz, room temperature, short reaction period and small amount of catalyst). The catalyst also shows excellent reusability in the reaction. The crystalline phases present in the catalyst are mixed oxides and hydroxides of nickel and iron. The high catalytic activity of the decomposed Ni-Fe-hydrotalcite is attributed to the formation of uniformly distributed Ni-Fe metal oxides and hydroxides. (C) 2011 Elsevier B.V. All rights reserved.

10aAcid chlorides10aamines10aDecomposition of Ni-Fe-hydrotalcite10aN-acylation of amines10aNi-Fe-hydrotalcite derived catalyst1 aChoudhary, Vasant, R.1 aDumbre, Deepa, K. uhttps://library.ncl.res.in/content/thermally-decomposed-ni-fe-hydrotalcite-highly-active-catalyst-solvent-free-n-acylation-001309nas a2200229 4500008004100000022001400041245009600055210006900151260008600220300001400306490000700320520045200327653002300779653001400802653001100816653002000827653002900847653002800876100002800904700002200932856012500954 2013 eng d a0039-791100aEfficient bakers' yeast-catalyzed multicomponent synthesis of -aminophosphonates in one pot0 aEfficient bakers yeastcatalyzed multicomponent synthesis of amin a325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USAbTAYLOR & FRANCIS INCcOCT a2583-25890 v433 a

Utilizing bakers' yeast (Saccharomyces cerevisiae) as a biocatalyst, synthesis of -aminophosphonates in one pot has been accomplished by the three-component reaction of an aldehyde, an amine, and diethyl phosphite in moderate to good yields under solvent-free reaction conditions. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications (R) to view the free supplemental file.

10a-aminophosphonates10aaldehydes10aamines10agreen chemistry10aSaccharomyces cerevisiae10asolvent-free conditions1 aBhattacharya, Asish, K.1 aMujahid, Mohammad uhttps://library.ncl.res.in/content/efficient-bakers-yeast-catalyzed-multicomponent-synthesis-aminophosphonates-one-pot-001537nas a2200361 4500008004100000022001400041245007800055210006900133260000800202300001400210490000700224520045500231653002800686653001300714653001400727653001100741653001300752653002000765653002100785653003900806653002400845653002600869653001200895653001700907653001900924653002300943653002500966100002000991700001801011700001801029700002501047856010301072 2017 eng d a0039-788100aSimple cobalt(II) chloride catalyzed N-alkylation of amines with alcohols0 aSimple cobaltII chloride catalyzed Nalkylation of amines with al cSEP a3957-39610 v493 a

A facile cobalt-catalyzed N-alkylation of amines with alcohols using inexpensive, commercially available CoCl2 center dot 6H(2)O is reported. Employing this readily available cobalt catalyst, a variety of amines with wide functional group tolerance were selectively alkylated under benign conditions.

10a(Hetero)Aromatic Amines10aAlcohols10aAmination10aamines10aAnilines10aAromatic-amines10aCobalt Catalysis10aDehydrogenation Borrowing Hydrogen10aEfficient Catalysts10aHydrogen Autotransfer10aIridium10aN-alkylation10aPincer-complex10aSecondary Alcohols10aSelective Alkylation1 aMidya, Siba, P.1 aMondal, Akash1 aBegum, Ayesha1 aBalaraman, Ekambaram uhttps://library.ncl.res.in/content/simple-cobaltii-chloride-catalyzed-n-alkylation-amines-alcohols01366nas a2200217 4500008004100000022001400041245013500055210006900190260000900259300001400268490000900282520060200291653001400893653001100907653002200918653002100940653002100961100002000982700001901002856012701021 2020 eng d a1434-193X00aSynthesis of 2-azabicyclo[m.n.0]-alkanes and their application towards the synthesis of strychnos and stemona classes of alkaloids0 aSynthesis of 2azabicyclomn0alkanes and their application towards cJUL  a3883-38880 v20203 a

2-Azabicyclo[m.n.0]alkane ring systems, the conceptual precursors towards the synthesis of Strychnos and Stemona classes of alkaloids, were synthesized from tert-butyl 2-(phenylsulfonyl)-7-aza-bicyclo[2.2.1]hept-2-ene-7-carboxylate by alkyl Grignard reaction and intramolecular cyclisation of the in situ generated ring opening product 2. The synthesized cis-hexahydroindole 3 and cis-octahydro-benzo[b]azepine 5 scaffolds were utilized to construct the advanced intermediates 25 and 35, respectively, towards the synthesis of the corresponding Strychnos and Stemona classes of alkaloids.

10aalkaloids10aamines10aGrignard reaction10aMichael addition10aNatural products1 aMajumder, Binoy1 aPandey, Ganesh uhttps://library.ncl.res.in/content/synthesis-2-azabicyclomn0-alkanes-and-their-application-towards-synthesis-strychnos-and12211nas a2200289 45000080041000000220014000412450146000552100069002012600008002703000011002784900008002895201119900297653001111496653000811507653005211515653002111567100002011588700002311608700003011631700002511661700001911686700002211705700001811727700002111745700002711766856012811793 2021 eng d a1385-894700aGreen route for carbonylation of amines by CO2 using Sn-Ni-O bifunctional catalyst and theoretical study for finding best suited active sites0 aGreen route for carbonylation of amines by CO2 using SnNiO bifun cSEP a1294390 v4193 a

Reaction between n-alkylamine and CO2 has gained interest due to the demand for the dialkylurea for various applications. For the first time, the tool Mathematica was used to analyze the experimental data with an idea to derive an equation which determines the best suited active sites for any given input set of dependent parameters. The equation can further be used to predict the product yield with the known values of active sites for a reaction. Among several Sn containing mixed oxides, Sn-Ni oxide (Sn-Ni-O) was found to be the better performing catalyst. The studies indicate that the formation of new defect sites when NiO and SnO2 are in the mixed state and possibly a solid solution enhances the catalytic efficiency. There are two main reasons for improved catalytic performance; one, mixing of SnO2 into NiO which reduces the number of holes (h+) localized on lattice oxygen (O2−+ h+→ O•−) and two, smaller SnO2 particles are dispersed on the bigger particle NiO which alters the acidic and basic active sites in the catalyst. FT-IR adsorption study with amine and CO2 helped in deriving a plausible mechanism for this reaction. Under optimized reaction condition, Sn1.1-Ni-O-600 gave 77.3% of n-butylamine conversion and 75.7% of yield for 1,3-dibutylurea. The versatility of the catalyst was tested for carbonylation of different aliphatic and aromatic amines, diamine and hydroxy amine with CO2.

10aamines10aCO210aMixed oxide catalyst and bi-functional catalyst10aSubstituted urea1 aKulal, Nagendra1 aVetrivel, Rajappan1 aGopinath, Chinnakonda, S.1 aRavindran, Rahul, K.1 aRao, Vinod, N.1 aShetty, Manjunath1 aShrikanth, R.1 aRangappa, Dinesh1 aShanbhag, Ganapati, V. uhttps://library.ncl.res.in/content/green-route-carbonylation-amines-co2-using-sn-ni-o-bifunctional-catalyst-and-theoretical00798nas a2200253 4500008004100000022001400041245008900055210006900144260000800213300001200221490000700233653001100240653001300251653001300264653001500277653001300292653001600305653001500321100002200336700002200358700002500380700002200405856011700427 2024 eng d a0098-033100aTyramine-mediated hyperactivity modulates the dietary habits in Helicoverpa armigera0 aTyraminemediated hyperactivity modulates the dietary habits in H cOCT a453-4640 v5010aamines10aBehavior10adopamine10aoctopamine10aRECEPTOR10asensitivity10aSULFAKININ1 aPatil, Yogita, P.1 aGawari, Shyam, K.1 aBarvkar, Vitthal, T.1 aJoshi, Rakesh, S. uhttps://library.ncl.res.in/content/tyramine-mediated-hyperactivity-modulates-dietary-habits-helicoverpa-armigera