01969nas a2200241 4500008004100000022001400041245009300055210006900148260006900217300001000286490000800296520112200304653002301426653002501449653001101474653001801485100001901503700002101522700002001543700001801563700002901581856011701610 2008 eng d a0254-058400aSynthesis of oleic acid capped copper nano-particles via reduction of copper salt by SFS0 aSynthesis of oleic acid capped copper nanoparticles via reductio aPO BOX 564, 1001 LAUSANNE, SWITZERLANDbELSEVIER SCIENCE SAcJUL a21-250 v1103 a

Synthesis of oleic acid capped copper nano-particles has been carried out by use of sodium formaldehyde sulfoxylate (SFS) in aqueous medium. Nano-copper can be effectively coated with polyvinyl alcohol (PVA). Phase-pure nano-Cu can be obtained when water/acetone was used as aqueous medium. It is observed that the surface plasmon resonance (SPR) phenomena can be controlled during synthesis by the use of suitable reagent system, e.g. absorption band in presence of PVA can be blue shifted. As-prepared copper nano-particles were characterized by X-ray diffraction measurements (XRD), Scanning electron microscopy (SEM), energy dispersive analysis of X-rays (EDAX), thermo gravimetric analysis (TGA) and Fourier transform infra-red spectroscopy (FTIR). XRD analysis revealed broad pattern for fcc crystal structure of copper metal. The particle size by use of Scherrer's equation was calculated to be about 20 nm. TGA revealed similar to 10% weight loss due to the presence of surfactant. FTIR spectroscopy confirmed the presence of oleic acid around the particles. (c) 2008 Elsevier B.V. All rights reserved.

10aChemical synthesis10aelectronic materials10ametals10aNanostructure1 aKhanna, P., K.1 aKale, Trupti, S.1 aShaikh, Mushtaq1 aRao, Koteswar1 aSatyanarayana, C., V. V. uhttps://library.ncl.res.in/content/synthesis-oleic-acid-capped-copper-nano-particles-reduction-copper-salt-sfs-002151nas a2200265 4500008004100000022001400041245013600055210006900191260010200260300001000362490000800372520114400380653002401524653001101548653001501559653002501574653001701599100002401616700002501640700001601665700002601681700002801707700002201735856012801757 2014 eng d a0011-389100aCulturable bacterial phylogeny from a shallow water hydrothermal vent of espalamaca (Faial, Azores) reveals a variety of novel taxa0 aCulturable bacterial phylogeny from a shallow water hydrothermal aC V RAMAN AVENUE, SADASHIVANAGAR, P B \#8005, BANGALORE 560 080, INDIAbINDIAN ACAD SCIENCEScJAN a58-690 v1063 a

Phylogenetic diversity of the 16S rRNA gene associated with the domain bacteria was examined at the level of operational taxonomic units (OTUs) using the rarefaction analysis from a newly identified shallow water hydrothermal vent, Espalamaca in the Azorean Island Faial (Horta), North Atlantic Ocean. Diluted sea water nutrient agar amended with metals manganese, lead, iron and element sulphur, could help in retrieving highest OTUs (95) from the vent and 39 OTUs from nonvent. Molecular tools implemented on bacterial census indicated the occupancy of gamma-Proteobacteria by 55.78%, alpha-Proteobacteria by 21.05% and 12.63% of Bacteroidetes in the total population. Occurrence of novel species maximized with alpha-Proteobacteria (11/20) followed by Bacteroidetes (5/12) signified the necessity of studying these groups to strengthen the biodiversity database. Shannon index (H') and the Chao I richness estimator illustrated a strong bacterial community in the venting area. The current study confers many bacterial genera which were not reported earlier in any of the shallow water vents and adds 33 new taxa to the database.

10aBacterial phylogeny10ametals10anovel taxa10ararefaction analysis10ashallow vent1 aRajasabapathy, Raju1 aMohandass, Chellandi1 aColaco, Ana1 aDastager, Syed, Gulam1 aSantos, Ricardo, Serrao1 aMeena, Ram, Murti uhttps://library.ncl.res.in/content/culturable-bacterial-phylogeny-shallow-water-hydrothermal-vent-espalamaca-faial-azores-001956nas a2200253 4500008004100000022001400041245007600055210006900131260000900200300001400209490000800223520116500231653001601396653002401412653001101436653001501447653002001462653000801482100002801490700001601518700002501534700003601559856010701595 2020 eng d a0141-813000aTransition metal nickel prevents Tau aggregation in Alzheimer's disease0 aTransition metal nickel prevents Tau aggregation in Alzheimers d cAUG  a1359-13650 v1563 a

Alzheimer's disease is the leading cause of dementia, effecting majority of aged people worldwide. The multifaceted effectors of Alzheimer's disease primarily include Tau, amyloid-beta along with hyper activation of kinases, oxidative stress and mutations etc., makes it challenging to design therapeutics. Tau is a microtubule-associating protein, which is subjected to cellular stress resulting in the formation of neurofibrillary tangles, leading to loss of affinity for microtubules. This causes loss of microtubule stability and in turn alters axonal integrity. In the present work, emphasis towards understanding interaction of nickel with Tau was made. Metals such as iron, zinc, copper and lead etc., are known to modulate Tau conformation and enhance its aggregation. Our results showed the deliverance of Tau aggregation by nickel and its synthetic morpholine conjugate. Nickel prevents aggregation by inducing degradation of Tau as evidenced by SDS-PAGE and TEM. Nickel and the synthetic conjugate being non toxic to neuro2a cells and prevent Tau aggregation, might direct these complexes to overcome AD. (C) 2019 Published by Elsevier B.V.

10aAggregation10aAlzheimer's disease10ametals10aMorpholine10aNickel chloride10aTau1 aGorantla, Nalini, Vijay1 aDas, Rashmi1 aBalaraman, Ekambaram1 aChinnathambi, Subashchandrabose uhttps://library.ncl.res.in/content/transition-metal-nickel-prevents-tau-aggregation-alzheimers-disease