01907nas a2200241   4500008004100000022001400041245012600055210006900181260007300250300001200323490000800335520103600343653001701379653001801396653001801414653001901432100001601451700002401467700002001491700001901511700001801530856011701548       2007                        eng d  a1381-116900aSulfonic acid functionalized mesoporous silicas and organosilicas: synthesis, characterization and catalytic applications0 aSulfonic acid functionalized mesoporous silicas and organosilica  aPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSbELSEVIER SCIENCE BVcSEP  a153-1580 v2743 a<p>Ethane bridged mesoporous organosilicas and MCM-41 having sulfonic acid groups in the pore channels were prepared by co-condensation method as well as grafting method, using 3-mercaptopropyltriethoxysilane (3-MPTS) as the sulfur precursor. TEM and N-2 sorption isotherm analysis revealed that the mesoporous structural ordering is retained after the functionalization and modifications of organic groups while FT-IR, Raman, XPS and solid-state C-13 CP MAS NMR shows the presence of sulfonic acid groups and the stability of the mesoporous framework. The catalytic activity of the developed materials was evaluated in the liquid phase Claisen-Schmidt condensation reaction of acetophenone with benzaldehyde, to probe the effect of mesoporous support surfaces as well as the role of preparation methods. Results showed that sulfonic acid functionalized ethane-silica samples were more active, selective and stable than the conventional sulfonic acid containing mesoporous catalysts. (c) 2007 Elsevier B.V. All rights reserved.</p>10acondensation10aethane-silica10aheterogeneity10asulfonic acids1 aShylesh, S.1 aSamuel, Prinson, P.1 aSrilakshmi, Ch.1 aParischa, Renu1 aSingh, A., P.  uhttps://library.ncl.res.in/content/sulfonic-acid-functionalized-mesoporous-silicas-and-organosilicas-synthesis-002010nas a2200265   4500008004100000022001400041245010100055210006900156260007300225300001400298490000600312520107800318653002301396653001701419653001401436653001401450653002401464653001501488100002301503700002801526700001701554700001901571700002301590856013101613       2007                        eng d  a1566-736700aSynthesis of tinidazole by condensation-oxidation sequence using MoO3/SiO2 bifunctional catalyst0 aSynthesis of tinidazole by condensationoxidation sequence using   aPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSbELSEVIER SCIENCE BVcOCT  a1550-15550 v83 a<p>Antimicrobial drug, tinidazole has been synthesized by condensation of 2-methyl,5-nitro-imidazole and 2-ethyl-thio-ethanol over MoO3/SiO2 catalyst to obtain 1-(2-ethyl-thio-ethanol)-2-methyl-5-nitro-imidazole which is further oxidized using hydrogen peroxide using the same MoO3/SiO2 catalyst to obtain tinidazole. MoO3/SiO2 catalyst (20%), synthesized by sol-gel process showed the highest acid strength and was successfully demonstrated to catalyze both condensation and oxidation in the synthesis of tinidazole. Due to the bifunctional activity of the catalyst, the use of acetic acid for condensation step and tungstic acid or ammonium molybdate for oxidation step in the conventional synthesis of tinidazole could be eliminated, thus making it an environmentally benign process. The catalysts could be recycled five times without any appreciable loss in the conversion and selectivity showing the potential for. the use of MoO3/SiO2 as bifunctional catalyst for the production of this industrially important compound. (C) 2007 Elsevier B.V. All rights reserved.</p>10aantimicrobial drug10acondensation10aMoO3/SiO210aOxidation10asolid acid catalyst10atinidazole1 aChandorkar, J., G.1 aUmbarkar, Shubhangi, B.1 aRode, C., V.1 aKotwal, V., B.1 aDongare, Mohan, K.  uhttps://library.ncl.res.in/content/synthesis-tinidazole-condensation-oxidation-sequence-using-moo3sio2-bifunctional-catalyst-000999nas a2200193   4500008004100000022001400041245007800055210006900133260007500202300001400277520025800291653002800549653001700577653004000594653002400634100001800658700001900676856011000695       2008                        eng d  a0039-788100aSynthesis of norpandamarilactonines, pandamarilactonines, and pandanamine0 aSynthesis of norpandamarilactonines pandamarilactonines and pand  aRUDIGERSTR 14, D-70469 STUTTGART, GERMANYbGEORG THIEME VERLAG KGcMAY  a1455-14593 a<p>A facile route to naturally occurring (+/-)-norpandamarilactonines A and B, (+/-)-pandamarilactonines A-D, and pandanamine has been described from 3-methylfuran-2(5H)-one, with a reductive intramolecular aza-Michael-type addition as the key step.</p>10a3-methylfuran-2(5H)-one10acondensation10aintramolecular aza-Michael reaction10apandamarilactonines1 aGogoi, Sanjib1 aArgade, N., P.  uhttps://library.ncl.res.in/content/synthesis-norpandamarilactonines-pandamarilactonines-and-pandanamine-001728nas a2200289   4500008004100000022001400041245009000055210006900145260010600214300001400320490000700334520072600341653001301067653001801080653001701098653001701115653002101132653001701153653002501170653001401195100002801209700002701237700002201264700001601286700002101302856011501323       2009                        eng d  a0960-894X00aSynthesis and in vitro study of 14-aryl-14H-dibenzo[a.j]xanthenes as cytotoxic agents0 aSynthesis and in vitro study of 14aryl14Hdibenzoajxanthenes as c  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcOCT  a5590-55930 v193 a<p>A simple and expedient method for the synthesis of a series of 14-aryl-14H-dibenzo[a.j]xanthenes is described through a one-pot condensation of beta-naphthol with aryl aldehydes catalysed by TaCl(5) under solvent-free conventional heating. The major advantages of the present method are: high yields, less reaction time, solvent-free condition and easy purification of the products. The synthesized 14-aryl-14H-dibenzo[a.j]xanthenes were evaluated against a panel of six human cancer lines of different tissues. Synthesized compound 30 showed IC(50) of 37.9 and 41.3 mu M against Colo-205 and 502713, respectively, whereas 3g showed IC(50) of 41.9 mu M against Colo-205. (C) 2009 Elsevier Ltd. All rights reserved.</p>10aAldehyde10abeta-Naphthol10acondensation10aCytotoxicity10aOne-pot reaction10aSolvent-free10aTantalum(V) chloride10aXanthenes1 aBhattacharya, Asish, K.1 aRana, Kalpeshkumar, C.1 aMujahid, Mohammad1 aSehar, Irum1 aSaxena, Ajit, K.  uhttps://library.ncl.res.in/content/synthesis-and-vitro-study-14-aryl-14h-dibenzoajxanthenes-cytotoxic-agents-001192nas a2200241   4500008004100000022001400041245011800055210006900173260008600242300001800328490000700346520026200353653001900615653002800634653002000662653001700682653002000699100002300719700001900742700002800761700002900789856013200818       2010                        eng d  a0039-791100aHighly selective claisen-schmidt condensation catalyzed by silica chloride under solvent-free reaction conditions0 aHighly selective claisenschmidt condensation catalyzed by silica  a325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USAbTAYLOR & FRANCIS INCcAUG  aPII 9263088530 v403 a<p>Silica chloride serves as a useful catalyst in the cross-aldol condensation, leading to the synthesis of a wide variety of bisarylidene cycloalkanones and chalcones. The catalyst showed high selectivity; self-condensation of ketones was not observed.</p>10aAldol reaction10aarylidene cycloalkanone10aClaisen-Schmidt10acondensation10asilica chloride1 aHazarkhani, Hassan1 aKumar, Pradeep1 aKondiram, Kadam, Sachin1 aGadwal, Ikhlas, M. Shafi  uhttps://library.ncl.res.in/content/highly-selective-claisen-schmidt-condensation-catalyzed-silica-chloride-under-solvent-free-000863nas a2200241   4500008004100000022001400041245002900055210002900084260010300113300001400216490000700230520015000237653002000387653002100407653001600428653001700444653001900461653002100480653001400501100002400515700001900539856006300558       2014                        eng d  a0376-469900aSynthesis of chenopanone0 aSynthesis of chenopanone  aANUSANDHAN BHAWAN, 2 RAFI MARG, NEW DELHI, 110001, INDIAbCOUNCIL SCIENTIFIC & INDUSTRIAL REScAUG  a1140-11420 v533 a<p>Starting from glyoxalic acid, a facile three step approach to chenopanone has been described utilizing the Barbier reaction as a key step.</p>10aacid hydrolysis10aBarbier reaction10achenopanone10acondensation10aGlyoxalic acid10aisovaleraldehyde10asynthesis1 aDeore, Prashant, S.1 aArgade, N., P.  uhttps://library.ncl.res.in/content/synthesis-chenopanone-001281nas a2200241   4500008004100000022001400041245006700055210006700122260000800189300001200197490000700209520049300216653002700709653002000736653001700756653002200773653002300795653001800818653004800836100003000884700002600914856009900940       2019                        eng d  a0376-469900aStereoselective synthesis of subincanadine alkaloids framework0 aStereoselective synthesis of subincanadine alkaloids framework  cJUN  a669-6730 v583 aStarting from, N-tosyltryptamine and (S)-acetoxysuccinic anhydride, a facile synthesis of (-)-indolizinoindolone has been demonstrated as a basic structural outline of bioactive subincanadine alkaloids. Regioselective Grignard reaction with (S)-acetoxysuccinimide, stereoselective intramolecular cyclization to form (-)-indolizinoindolone skeleton and TiCl4 induced condensation with acetaldehyde for stereoselective generation of exocyclic carbon carbon double bond are the key features.10a(S)-Acetoxysuccinimide10aalane reduction10acondensation10aGrignard reaction10aindolizinoindolone10aPCC-oxidation10astereoselective Pictet-Spengler cyclization1 aKalshetti, Manojkumar, G.1 aArgade, Narshinha, P.  uhttps://library.ncl.res.in/content/stereoselective-synthesis-subincanadine-alkaloids-framework01736nas a2200241   4500008004100000022001400041245010800055210006900163260000800232300001100240490000800251520094200259653001701201653001501218653001301233653002101246653001301267653001901280100001901299700002601318700002401344856012601368       2020                        eng d  a1385-894700aUnderstanding the role of solvent properties on reaction kinetics for synthesis of silica nanoparticles0 aUnderstanding the role of solvent properties on reaction kinetic  cOCT  a1254270 v3983 a<p>The effect of various alcoholic solvents and their compositions on the size of silica particles synthesized through hydrolysis and condensation of tetraethyl orthosilicate (TEOS) is studied. The alcohols used are: Methanol, ethanol, propanol, i-propanol, butanol, pentanol, hexanol, octanol, decanol and do-decanol. Ethanol was used as a co-solvent with the higher molecular weight alcohols. Silica particles of size between 100 nm and 2 mu m were obtained by changing solvent composition. Concentrations of total soluble silica and silicic acid were measured and used for exploring the kinetics of hydrolysis and condensation reactions. Polarity, steric hindrance and viscosity of solvent were found to have a strong influence on the rate constants and size of silica nanoparticles. An attempt is made to correlate both final particle size and rate constants with dielectric constant, Wiener index and viscosity of the solvent.</p>
10acondensation10aHydrolysis10akinetics10asilica particles10aSolvents10aStober process1 aBari, Atul, H.1 aJundale, Rajashri, B.1 aKulkarni, Amol., A.  uhttps://library.ncl.res.in/content/understanding-role-solvent-properties-reaction-kinetics-synthesis-silica-nanoparticles