02050nas a2200229   4500008004100000022001400041245008000055210006900135260000800204300001200212490000800224520132400232653001301556653001701569653001501586653001001601653003201611100002101643700002301664700002401687856010901711       2024                        eng d  a1364-507200aRole and significance of virus-bacteria interactions in disease progression0 aRole and significance of virusbacteria interactions in disease p  cJUN  alxae1300 v1353 a<p>
	Understanding disease pathogenesis caused by bacteria/virus, from the perspective of individual pathogen has provided meaningful insights. However, as viral and bacterial counterparts might inhabit the same infection site, it becomes crucial to consider their interactions and contributions in disease onset and progression. The objective of the review is to highlight the importance of considering both viral and bacterial agents during the course of coinfection. The review provides a unique perspective on the general theme of virus-bacteria interactions, which either lead to colocalized infections that are restricted to one anatomical niche, or systemic infections that have a systemic effect on the human host. The sequence, nature, and underlying mechanisms of certain virus-bacteria interactions have been elaborated with relevant examples from literature. It also attempts to address the various applied aspects, including diagnostic and therapeutic strategies for individual infections as well as virus-bacteria coinfections. The review aims to aid researchers in comprehending the intricate interplay between virus and bacteria in disease progression, thereby enhancing understanding of current methodologies and empowering the development of novel health care strategies to tackle coinfections.</p>
10aBacteria10acoinfections10ainfections10avirus10avirus-bacteria interactions1 aPokhrel, Vatsala1 aKuntal, Bhusan, K.1 aMande, Sharmila, S.  uhttps://library.ncl.res.in/content/role-and-significance-virus-bacteria-interactions-disease-progression