01296nas a2200253   4500008004100000022001400041245012900055210006900184260000900253300001400262490000600276520044900282653000600731653002500737653001800762653002400780653002400804653001100828100001700839700002400856700002400880700001500904856012300919       2021                        eng d  a2365-654900aAcid mediated sulfonylation of para-quinone methides with tosylmethyl isocyanides for the synthesis of diarylmethyl sulfones0 aAcid mediated sulfonylation of paraquinone methides with tosylme  cJUL   a7158-71610 v63 aAn efficient, hydrochloric acid promoted reaction for the synthesis of diarylmethyl sulfones has been developed via unprecedented 1, 6-conjugate addition reaction of tosylmethyl isocyanide (TosMIC) with para-quinone methides.This catalyst free reaction provides various diarylmethyl sulfones in good to excellent yields in an operationally simple method under metal free conditions. Further transformations of the productsare also demonstrated.10a110a6-Conjugate addition10aaromatization10aDiarylmethylsulfone10apara-Quinonemethide10aTosMIC1 aKumar, Pawan1 aKale, Someshwar, B.1 aGonnade, Rajesh, G.1 aDas, Utpal  uhttps://library.ncl.res.in/content/acid-mediated-sulfonylation-para-quinone-methides-tosylmethyl-isocyanides-synthesis01450nas a2200265   4500008004100000022001400041245016500055210006900220260000800289300001100297490000800308520050200316653000600818653002500824653001800849653002500867653002000892653002500912100002300937700002300960700002500983700002501008700001901033856013201052       2021                        eng d  a0040-402000aMetal-free, Tf2NH-catalyzed 1, 6-conjugate addition of imidazopyridine to para-quinone methides: easy access to C3-functionalized triarylmethane imidazopyridine0 aMetalfree Tf2NHcatalyzed 1 6conjugate addition of imidazopyridin  cNOV  a1325100 v1013 aAn inexpensive and commercially available Tf2NH-catalyzed 1,6-conjugate addition of imidazopyridine (IMPY) heterocycles to para-quinone methides (p-QMs) is reported. The present transformation provides a diverse class of C3-functionalized triarylmethanes heterocyclic derivatives of imidazopyridine. These metal-free transformations provided a very broad substrate scope of conjugate addition product with a high yield up to 97% within a short duration. (C) 2021 Elsevier Ltd. All rights reserved.10a110a6-Conjugate addition10aBronsted acid10aC3-functionalization10aImidazopyridine10apara-Quinone methide1 aKhonde, Nilesh, S.1 aSaid, Madhukar, S.1 aSabane, Jagjivan, K.1 aGajbhiye, Jayant, M.1 aKumar, Pradeep  uhttps://library.ncl.res.in/content/metal-free-tf2nh-catalyzed-1-6-conjugate-addition-imidazopyridine-para-quinone-methides-easy