01744nas a2200217   4500008004100000022001400041245007000055210006700125260000800192490000700200520104300207653002701250653001401277653001901291653003101310653001301341100002101354700002401375700002401399856010301423       2021                        eng d  a1527-899900aGold-catalysed nitroalkyne cycloisomerization - synthetic utility0 aGoldcatalysed nitroalkyne cycloisomerization synthetic utility  cDEC0 v213 a<p>The gold-catalysed intramolecular redox cyclization of o-alkynylnitrobenzens documented by Professors Naoki Asao and Yoshinori Yamamoto is an important discovery that has opened two complementary research domains. Advancing this cyclization with other metals as well as developing new methods around the products that result from this reaction is one aspect that has seen growing interest. On the other hand, the idea of generating alpha-oxo gold carbenes via oxygen transfer to alkynes has established another important aspect in gold-catalysis. In this account, we will be dealing with the first aspect, which revolves around the internal redox cyclization of nitroalkynes (trivially called as nitroalkyne cycloisomerization), focusing mainly on the gold-complexes and the synthetic methods developed around it from our group and from other groups, and also providing the details of similar transformations documented with other metals so that the complementary reactivity/diversity of these transformations could be appreciated.</p>10aalpha-Oxo Gold Carbene10aAnthranil10aGold-catalysis10aInternal Redox Cyclization10aIsatogen1 aDhote, Pawan, S.1 aHalnor, Swapnil, V.1 aRamana, Chepuri, V.  uhttps://library.ncl.res.in/content/gold-catalysed-nitroalkyne-cycloisomerization-synthetic-utility01655nas a2200241   4500008004100000022001400041245008100055210006900136260000800205300001100213490000600224520087900230653002701109653002301136653002001159653001901179653001901198100001501217700002401232700001701256700002701273856011301300       2021                        eng d  a2296-264600aGold-catalyzed complementary nitroalkyne internal redox process: a DFT study0 aGoldcatalyzed complementary nitroalkyne internal redox process a  cJUL  a6897800 v93 aGold-catalysis, in this century, is one of the most emerging and promising new areas of research in organic synthesis. During the last two decades, a wide range of distinct synthetic methodologies have been unveiled employing homogeneous gold catalysis and aptly applied in the synthesis of numerous natural products and biologically active molecules. Among these, the reactions involving alpha-oxo gold carbene/alpha-imino gold carbene intermediates are of contemporary interest, in view of their synthetic potential and also due to the need to understand the bonding involved in these complexes. In this manuscript, we document the theoretical investigations on the regio-selectivity dependence of substitution on the gold-catalyzed cycloisomerization of o-nitroarylalkyne derivatives. We have also studied the relative stabilities of alpha-oxo gold carbene intermediates.10aalpha-Oxo Gold Carbene10acycloisomerization10aDFT calculation10aGold-catalysis10ainternal redox1 aRaj, Vipin1 aDhote, Pawan, S. S.1 aVanka, Kumar1 aRamana, Chepuri, V. V.  uhttps://library.ncl.res.in/content/gold-catalyzed-complementary-nitroalkyne-internal-redox-process-dft-study