01578nas a2200169   4500008004100000245011800041210006900159260000800228300000900236490000700245520095900252100001901211700001901230700001901249700001901268856012101287       2015                        eng d00aAnalyzing different acetyl co-a metabolizing enzymes as potential drug targets against mycobacterium tuberculosis0 aAnalyzing different acetyl coa metabolizing enzymes as potential  cSEP  a1-150 v103 a<p>Mycobacterium tuberculosis, the causative agent of tuberculosis, is responsible for the deaths of million people around the globe. The scenario is worse than ever due to the emergence of drug resistant strains which are widely spread throughout the globe in much faster ways. To control this worst situation, we need to speed up the search for novel drugs which can specifically kill drug resistant bacteria in collaborative ways amongst academic, clinician and industry. Among different metabolic pathways, fatty acid synthesis pathway has always been a very attractive area for the drug target because of its crucial role during the infection and further in long term survival of pathogen inside the human host. In this review article, we analyzed the role of important and crucial enzymes, which are responsible for the influx and efflux of acetyl co-A substrate, a central hub of metabolites, as potential drug targets against M. tuberculosis.</p>1 aAkhtar, Shamim1 aSingh, Sheetal1 aKumar, Santosh1 aSarkar, Dhiman  uhttps://library.ncl.res.in/content/analyzing-different-acetyl-co-metabolizing-enzymes-potential-drug-targets-against