01183nas a2200157   4500008004100000022001400041245012700055210006900182260007100251300001400322490000700336520050200343100002500845700002400870856013100894       2016                        eng d  a1523-706000aNucleophilic nitration of arynes by sodium nitrite and its multicomponent reaction leading to double-functionalized arenes0 aNucleophilic nitration of arynes by sodium nitrite and its multi  a1155 16TH ST, NW, WASHINGTON, DC 20036 USAbAMER CHEMICAL SOCcJUN  a3010-30130 v183 a<p>An unusual nucleophilic nitration of arynes by NaNO2 in the presence of water has been developed, and the concept was further demonstrated to accomplish a double functionalization of arynes using a multicomponent reaction protocol to synthesize pharmaceutically important (2-nitrophenyl)methanol derivatives. Such substitution ortho to -NO2 is difficult by other means. The reaction conditions are mild and avoid the use of strong acids, expensive transition metal catalysts, and additives.</p>1 aDhokale, Ranjeet, A.1 aMhaske, Santosh, B.  uhttps://library.ncl.res.in/content/nucleophilic-nitration-arynes-sodium-nitrite-and-its-multicomponent-reaction-leading-double01025nas a2200145   4500008004100000245013000041210006900171260000800240300001400248490000700262520043200269100002500701700002400726856012900750       2017                        eng d00aDiversity-oriented synthesis of spiroannulated benzofuran-3-one scaffold of leptosphaerin C and congeners via aryne insertion0 aDiversityoriented synthesis of spiroannulated benzofuran3one sca  cMAY  a4875-48820 v823 aA concise synthesis of functionalized cyclohexenone-fused spirobenzofuran-3-ones under mild reaction conditions was developed. The reaction proceeds via insertion of aryne into the C-O bond followed by a regioselective intramolecular conjugate addition. The use of silyl-protected acid was crucial for the transformation. This protocol was successfully applied for the synthesis of leptosphaerin C core and its novel analogues.1 aDhokale, Ranjeet, A.1 aMhaske, Santosh, B.  uhttps://library.ncl.res.in/content/diversity-oriented-synthesis-spiroannulated-benzofuran-3-one-scaffold-leptosphaerin-c-and01514nas a2200241   4500008004100000022001400041245005800055210005600113260000800169300000900177490000700186520081800193653001501011653001101026653001801037653001401055653001901069653002101088653002101109100002501130700002401155856009301179       2018                        eng d  a0039-788100aTransition-metal-catalyzed reactions involving arynes0 aTransitionmetalcatalyzed reactions involving arynes  cJAN  a1-160 v503 a<p>The plethora of transformations attainable by the transition-metal-catalyzed reactions of arynes has found immense contemporary interest in the scientific community. This review highlights the scope and importance of transition-metal-catalyzed aryne reactions in the field of synthetic organic chemistry reported to date. It covers transformations achieved by the combination of arynes and various transition metals, which provide a facile access to a biaryl motif, fused polycyclic aromatic compounds, different novel carbocycles, various heterocycles, and complex natural products. 1 Introduction 2 Insertion of Arynes 3 Annulation of Arynes 4 Cycloaddition of Arynes 5 Multicomponent Reactions of Arynes 6 Miscellaneous Reactions of Arynes 7 Total Synthesis of Natural Products Using Arynes 8 Conclusion</p>10aannulation10aarynes10aCycloaddition10aInsertion10amulticomponent10aNatural products10aTransition Metal1 aDhokale, Ranjeet, A.1 aMhaske, Santosh, B.  uhttps://library.ncl.res.in/content/transition-metal-catalyzed-reactions-involving-arynes