01792nas a2200217 4500008004100000022001400041245009300055210006900148260011000217300001400327490000700341520097000348100002401318700001701342700001701359700001701376700002601393700001901419700001701438856011901455 2007 eng d a0959-942800aBio-milling technique for the size reduction of chemically synthesized BiMnO3 nanoplates0 aBiomilling technique for the size reduction of chemically synthe aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcAUG a3910-39140 v173 a

Wet- chemical techniques for the synthesis of complex oxide materials have advanced significantly; however, achieving finely dispersed nanoparticles with sizes less than 10 nm still remains challenging, especially for the perovskite family of compounds. On the other hand, a fungusmediated synthesis technique has recently shown potential to synthesize perovskites such as BaTiO3 with sizes as small as 5 nm. Here we report, for the first time, the use of fungal biomass, at room temperature, to break down chemically synthesized BiMnO3 nanoplates ( size similar to 150 - 200 nm) into very small particles (, 10 nm) while maintaining their crystalline structure and the phase purity. This novel technique that we have named as `` bio- milling'' holds immense potential for synergically utilizing both chemical and biological synthesis techniques to synthesize complex oxide nanoparticles with particle sizes less than 10 nm with the proper crystalline phase.

1 aMazumder, Baishakhi1 aUddin, Imran1 aKhan, Shadab1 aRavi, Venkat1 aSelvraj, Kaliaperumal1 aPoddar, Pankaj1 aAhmad, Absar uhttps://library.ncl.res.in/content/bio-milling-technique-size-reduction-chemically-synthesized-bimno3-nanoplates-001892nas a2200265 4500008004100000022001400041245007000055210006900125260009500194300001400289490000600303520100600309653001701315653001001332653002601342653002401368653001801392100001701410700002701427700001501454700001701469700001701486700001901503856010401522 2008 eng d a1533-488000aStructure and microbial synthesis of sub-10 nm Bi2O3 nanocrystals0 aStructure and microbial synthesis of sub10 nm Bi2O3 nanocrystals a25650 NORTH LEWIS WAY, STEVENSON RANCH, CA 91381-1439 USAbAMER SCIENTIFIC PUBLISHERScAUG a3909-39130 v83 a

After the advent of novel chemical and microbial techniques, providing control over grain size and shape of the nanomaterials, several binary-oxide materials have been explored in size less than 10 nm for their tunable physical properties. Bi2O3 nanoparticles have also redrawn attention due to their excellent properties, mostly as optoelectronic material. Here, we report the room-temperature biosynthesis of Bi2O3 nanoparticles in a size range of 5-8 nm by extra-cellularly challenging the plant pathogenic fungus-Fusarium oxysporum with the bismuth nitrate as precursor. The as-synthesized particle-surfaces are inherently functionalized by a robust layer of proteins which provides them very good stability in the aqueous medium. Structural investigation using selected area electron diffraction, high resolution transmission electron microscopy and powder XRD shows that particles are almost perfectly single crystalline and primarily crystallize in alpha-phase with monoclinic structure.

10aBiosynthesis10afungi10aHigh Refractive Index10aHigh Resolution TEM10aNanoparticles1 aUddin, Imran1 aAdyanthaya, Suguna, D.1 aSyed, Asad1 aSelvaraj, K.1 aAhmad, Absar1 aPoddar, Pankaj uhttps://library.ncl.res.in/content/structure-and-microbial-synthesis-sub-10-nm-bi2o3-nanocrystals-002200nas a2200145 4500008004100000245016100041210006900202260000800271300001200279490000600291520158900297100001701886700001901903856013201922 2013 eng d00aExtracellular biosynthesis of water dispersible, protein capped Mn5O8 nanoparticles using the fungus fusarium oxysporum and study of their magnetic behavior0 aExtracellular biosynthesis of water dispersible protein capped M cJUN a91 - 970 v33 a

Nanomaterials of different sizes, shapes and compositions are being synthesized by various chemical, physical and biological routes. The pressing need of the hour is to have a synthesis protocol which does not harm the environment in any way and is inexpensive so that the benefits can be reaped by all. In this regard, the biological synthesis routes weigh over the chemical and physical ones which are toxic and expensive respectively. The biological routes occur at ambient conditions of temperature, pressure and pH and help protect the ecosystem as these do not employ any hazardous chemicals. Moreover, the nanoparticles obtained via biological routes are naturally protein capped which prevents their agglomeration and helps them retain their shape, size and stability for several months. One such important material is manganese oxide (Mn5O8) which at the nanoscale, has found good use in catalysis and as ionic conductors in fuel cells or batteries. The compound Mn5O8 exists in mixed valences of Mn2+ and Mn4+ and has drawn attention due to its antiferromagnetic nature. Here we report extracellular biosynthesis of manganese oxide (Mn5O8 nanoparticles in the size range of 10–11 nm at room temperature by challenging the fungus Fusarium oxysporum with manganese (II) acetate tetrahydrate [(CH3CO2)2 Mn · 4H2O] as precursor. The Mn5O8 nanoparticles so formed were characterized by TEM, XRD, FTIR, XPS, and TGA. Two mixed manganese ion valencies (Mn2+ and Mn4+) of Mn5O8 have been confirmed by XPS studies and antiferromagnetic transitions by magnetic measurements.

1 aUddin, Imran1 aPoddar, Pankaj uhttps://library.ncl.res.in/content/extracellular-biosynthesis-water-dispersible-protein-capped-mn5o8-nanoparticles-using-fungus01474nas a2200157 4500008004100000245011000041210006900151260000800220300000800228490000600236520089500242100001701137700002001154700001901174856012301193 2013 eng d00aNovel green bio-milling technique for the synthesis of BaTiO3 nanoparticle using Saccharomyces cerevisiae0 aNovel green biomilling technique for the synthesis of BaTiO3 nan cJAN a1-50 v23 aThe development of a novel green top-down approach called bio-milling for synthesizing the oxide nanomaterials is an issue of topical interest. While a number of chemical processes are energy intensive and involve toxic chemicals. Here we report, at room temperature, bio-milling of chemically synthesized barium titinate (BaTiO3) particles by challenging the fungus Saccharomyces cerevisiae against aqueous solution of BaTiO3 to synthesize the biogenic nanoparticles. The extracellular breaking of microscaled BaTiO3 particles by extracellular biomolecules/proteins secreted by the fungus under stressed condition results in the formation of particles in nanoregime. XRD spectra and TEM analysis showed that BaTiO3 particles reduce to their size during the interaction with the fungus Saccharomyces cerevisiae and maintaining their phase and crystallinity after bio-milling process.1 aUddin, Imran1 aJaiswal, Adhish1 aPoddar, Pankaj uhttps://library.ncl.res.in/content/novel-green-bio-milling-technique-synthesis-batio3-nanoparticle-using-saccharomyces01490nas a2200181 4500008004100000022001400041245018700055210006900242260000900311300001200320490000600332520077400338100002201112700001701134700001601151700001701167856012401184 2014 eng d a1932-620300aFungus-mediated preferential bioleaching of waste material such as fly - ash as a means of producing extracellular, protein capped, fluorescent and water soluble silica nanoparticles0 aFungusmediated preferential bioleaching of waste material such a cSEP  ae1075970 v93 a

In this paper, we for the first time show the ability of the mesophilic fungus Fusarium oxysporum in the bioleaching of waste material such as Fly-ash for the extracellular production of highly crystalline and highly stable, protein capped, fluorescent and water soluble silica nanoparticles at ambient conditions. When the fungus Fusarium oxysporum is exposed to Fly-ash, it is capable of selectively leaching out silica nanoparticles of quasi-spherical morphology within 24 h of reaction. These silica nanoparticles have been completely characterized by UV-vis spectroscopy, Photoluminescence (PL), Transmission electron microscopy (TEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) and Energy dispersive analysis of Xrays (EDAX).

1 aKhan, Shadab, Ali1 aUddin, Imran1 aMoeez, Sana1 aAhmad, Absar uhttps://library.ncl.res.in/content/fungus-mediated-preferential-bioleaching-waste-material-such-fly-ash-means-producing02606nas a2200181 4500008004100000245012400041210006900165260000800234300001400242490000700256520192700263100001702190700001702207700002602224700002602250700002002276856012802296 2016 eng d00aBiosynthesis of fluorescent Bi2S3 nanoparticles and their application as dual-functionSPECT-CT probe for animal imaging0 aBiosynthesis of fluorescent Bi2S3 nanoparticles and their applic cOCT a2019-20250 v163 aBismuth sulphide (Bi2S3) is an excellent semiconductor and its nanoparticles have numerous significant applications including photovoltaic materials, photodiode arrays, bio-imaging, etc. Nevertheless, these nanoparticles when fabricated by chemical and physical routes tend to easily aggregate in colloidal solutions, are eco-unfriendly, cumbrous and very broad in size distribution. The aim of the present manuscript was to ecologically fabricate water dispersible, safe and stable Bi2S3 nanoparticles such that these may find use in animal imaging, diagnostics, cell labeling and other biomedical applications. Herein, we for the first time have biosynthesized highly fluorescent, natural protein capped Bi2S3 nanoparticles by subjecting the fungus Fusarium oxysporum to bismuth nitrate pentahydrate [Bi(NO3)(3).5H(2)O] alongwith sodium sulphite (Na2SO3) as precursor salts under ambient conditions of temperature, pressure and pH. The nanoparticles were completely characterized using recognized standard techniques. These natural protein capped Bi2S3 nanoparticles are quasi-spherical in shape with an average particle size of 15 nm, maintain long term stability and show semiconductor behavior having blue shift with a band gap of 3.04 eV. Semiconductor nanocrystals are fundamentally much more fluorescent than the toxic fluorescent chemical compounds (fluorophores) which are presently largely employed in imaging, immunohistochemistry, biochemistry, etc. Biologically fabricated fluorescent nanoparticles may replace organic fluorophores and aid in rapid development of biomedical nanotechnology. Thus, biodistribution study of the so-formed Bi2S3 nanoparticles in male Sprague Dawley rats was done by radiolabelling with Technitium-99m (Tc-99m) and clearance time from blood was calculated. The nanoparticles were then employed in SPECT-CT probe for animal imaging where these imparted iodine equivalent contrast.1 aUddin, Imran1 aAhmad, Absar1 aSiddiqui, Ejaz, Ahmad1 aRahaman, Sk., Hasanur1 aGambhir, Sanjay uhttps://library.ncl.res.in/content/biosynthesis-fluorescent-bi2s3-nanoparticles-and-their-application-dual-functionspect-ct01471nas a2200181 4500008004100000022001400041245015500055210006900210260011000279300001400389490000700403520067100410100002501081700001701106700002501123700002101148856012001169 2016 eng d a1144-054600aPhysicochemical and antimicrobial photodynamic chemotherapy of unsymmetrical indium phthalocyanines alone or in the presence of magnetic nanoparticles0 aPhysicochemical and antimicrobial photodynamic chemotherapy of u aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcJAN a2710-27210 v403 a

An AB(3) type photosensitiser, consisting of 4-pyridylsulfanyl units (denoted as B-3) and one aminophenoxy (denoted as A) group (complex 3) was synthesized. Complex 3 was then quaternized to form complex 4. The aminophenoxy substituent of complex 3 was used for the formation of the amide linkage with the carboxylic functionalised magnetic nanoparticles. Complexes 3 and 4 and their conjugates with magnetic nanoparticles were then used for photodynamic antimicrobial chemotherapy on E. coli. The cationic photosensitiser 4 showed a high efficiency for photodynamic antimicrobial chemotherapy at a very low concentration compared to its conjugate on E. coli.

1 aOsifeko, Olawale, L.1 aUddin, Imran1 aMashazi, Philani, N.1 aNyokong, Tebello uhttps://library.ncl.res.in/content/physicochemical-and-antimicrobial-photodynamic-chemotherapy-unsymmetrical-indium01737nas a2200145 4500008004100000245008600041210006900127260000800196300001400204520119500218100002501413700001701438700002301455856011301478 2017 eng d00aBiomimetic synthesis of CdSe nanoparticles with potential bioimaging applications0 aBiomimetic synthesis of CdSe nanoparticles with potential bioima cJUN a2526-25323 aThis study presents in vitro biomimetic synthesis of CdSe nanoparticles using the enzyme, NADPH dependent-Nitrate reductase purified from fungus, Fusarium oxysporum. The synthesis of CdSe nanoparticles was accomplished in the presence of a synthetic peptide having amino acid sequence (γ-Glu-Cys-Glu-Cys)-Gly, which acted as binding molecule. The nanoparticles were synthesized in the size range of 3.9–9.0 nm was analysed using TEM. Further characterization of nanoparticles was done using techniques such as UV, PL, XPS, and FTIR. The as-synthesized CdSe nanoparticles were water dispersible containing free reactive amino groups. These CdSe nanoparticles were conjugated with bi-antennary and tri-antennary glycopeptides opening up the possibilities for their applications in bioimaging. These significant observations will help better understand the mechanism of biosynthesis of fluorescent nanoparticles using fungi. These findings promise an alternative strategy for an eco-friendly, economical, and large-scale synthesis of water dispersible CdSe nanoparticles. These CdSe nanoparticles have promising biomedical-imaging applications without a need for further functionalization.1 aAnsary, Abu, Ayoobul1 aUddin, Imran1 aKhan, Muhammed, I. uhttps://library.ncl.res.in/content/biomimetic-synthesis-cdse-nanoparticles-potential-bioimaging-applications