01616nas a2200193   4500008004100000022001400041245007500055210006900130260007100199300001400270490000700284520091900291100002001210700002001230700001501250700002001265700003001285856010701315       2005                        eng d  a0743-746300aGold nanoparticle networks with photoresponsive interparticle spacings0 aGold nanoparticle networks with photoresponsive interparticle sp  a1155 16TH ST, NW, WASHINGTON, DC 20036 USAbAMER CHEMICAL SOCcAUG  a7979-79840 v213 a<p>Photoresponsive gold nanoparticle networks were prepared by functionalizing them with azobenzene derivatives. A network can be formed when a linker molecule constituting the azobenzene moiety suitably derivatized on either side with gold surface sensitive groups such as thiols and amines is added to the nanoparticle solution. It is shown that the interparticle spacing in the networks could be controlled by the reversible trans-cis isomerization of the azobenzene moiety induced by UV and visible light, respectively. The photoinduced variation in the interparticle spacings is inferred by the changes in the optical spectra of the gold nanoparticles which display a red or blue shift in the surface plasmon resonance peak depending on a decrease or increase in the interparticle spacing, respectively. Transmission electron microscopy images are in consonance with the evidence from the optical spectra.</p>1 aSidhaye, D., S.1 aKashyap, Sudhir1 aSastry, M.1 aHotha, Srinivas1 aPrasad, Bhagavatula L. V.  uhttps://library.ncl.res.in/content/gold-nanoparticle-networks-photoresponsive-interparticle-spacings-000640nas a2200145   4500008004100000022001400041245009600055210006900151260007100220300002600291490000800317100002000325700002000345856012900365       2006                        eng d  a0002-786300aPropargyl glycosides as stable glycosyl donors: anomeric activation and glycoside syntheses0 aPropargyl glycosides as stable glycosyl donors anomeric activati  a1155 16TH ST, NW, WASHINGTON, DC 20036 USAbAMER CHEMICAL SOCcAUG  aArticle No. JA062425C0 v1281 aHotha, Srinivas1 aKashyap, Sudhir  uhttps://library.ncl.res.in/content/propargyl-glycosides-stable-glycosyl-donors-anomeric-activation-and-glycoside-syntheses-101131nas a2200169   4500008004100000022001400041245011800055210006900173260010600242300001400348490000700362520040500369100002000774700002900794700002000823856011800843       2007                        eng d  a0040-403900aSynthesis of C-2 methylene glycosides from C-2 propargyloxymethyl glycals exploiting the alkynophilicity of AuCl30 aSynthesis of C2 methylene glycosides from C2 propargyloxymethyl   aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcDEC  a8960-89620 v483 a<p>C-2 Methylene glycosides were synthesized from C-2 propargyloxymethyl glycals in a stereoselective manner using a catalytic quantity of AuCl3. The Au-catalyzed reaction was explored using various aglycones. The current protocol enables the preparation of C-2 methylene glycosides, tolerates diverse functional groups and is fast, catalytic and mild. (c) 2007 Elsevier Ltd. All rights reserved.</p>1 aKashyap, Sudhir1 aVidadala, Srinivasa, Rao1 aHotha, Srinivas  uhttps://library.ncl.res.in/content/synthesis-c-2-methylene-glycosides-c-2-propargyloxymethyl-glycals-exploiting-002309nas a2200217   4500008004100000022001400041245011600055210006900171260007100240300001400311490000700325520147400332100002501806700002201831700002001853700001901873700003001892700002001922700001801942856013101960       2009                        eng d  a0743-746300aDendritic effect of ligand-coated nanoparticles: enhanced apoptotic activity of silica-berberine nanoconjugates0 aDendritic effect of ligandcoated nanoparticles enhanced apoptoti  a1155 16TH ST, NW, WASHINGTON, DC 20036 USAbAMER CHEMICAL SOCcFEB  a2339-23470 v253 a<p>We describe the synthesis and biological characterization of a novel prototype, namely, silica nanoconjugates bearing a covalently linked berberine, a plant alkaloid known to have antiproliferative activity. The effect of synthesized nanoconjugates on cell proliferation, the cell cycle profile, and apoptosis in the human cervical carcinoma cell line (HeLa), human hepatocellular liver carcinoma cell line (HepG2), and human embryonic kidney (HEK) 293T cell line has been studied and compared with the results obtained for free berberine. Our results show that all the nanoconjugates display higher antiproliferative activity than free berberine. The ability of these nanoconjugates to inhibit cellular proliferation is mediated by the cell cycle arrest at the G1 phase. Moreover, silica nanoconugates caused selective apoptotic arrest with a higher efficiency than free berberine followed by apoptotic cell death as shown by quantitative fluorescence-activated cell sorting analyses. Efficiency of the nanoconjugates increases upon an increase in the linker chain length, demonstrating the distinct role of the spacer chain that conjugates nanoparticles and ligands. The actual reason to show enhanced efficiency by the nanoconjugates has not been elucidated in the present study; however, we hypothesize that an increase in local concentration due to the confinement of a ligand on the nanosurface (''dendritic'' effect) might have led to the observed effect.</p>1 aHalimani, Mahantappa1 aChandran, Prathap1 aKashyap, Sudhir1 aJadhav, V., M.1 aPrasad, Bhagavatula L. V.1 aHotha, Srinivas1 aMaiti, Souvik  uhttps://library.ncl.res.in/content/dendritic-effect-ligand-coated-nanoparticles-enhanced-apoptotic-activity-silica-berberine-0