01091nas a2200157   4500008004100000022001400041245012300055210006900178260010600247300001400353490000700367520038500374100002200759700002200781856013000803       2008                        eng d  a0040-403900aCo-catalyzed mild and chemoselective reduction of phenyl esters with NaBH(4): a practical synthesis of (R)-tolterodine0 aCocatalyzed mild and chemoselective reduction of phenyl esters w  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcJUN  a3790-37930 v493 a<p>CoCl(2) catalyzes effectively the chemoselective reduction of phenyl carboxylic esters to the corresponding saturated alcohols in high yields using NaBH(4) at ambient conditions. By employing this methodology, the synthesis of (R)-tolterodine, a muscarinic receptor antagonist, has been achieved in high yield and optical purity. (C) 2008 Elsevier Ltd. All rights reserved.</p>1 aJagdale, Arun, R.1 aSudalai, Arumugam  uhttps://library.ncl.res.in/content/co-catalyzed-mild-and-chemoselective-reduction-phenyl-esters-nabh4-practical-synthesis-r-001180nas a2200217   4500008004100000022001400041245014300055210006900198260010300267300001400370490000700384520030400391653001400695653001400709653001100723653002800734100002200762700002800784700002200812856012800834       2008                        eng d  a0376-469900aCu(OTf)(2) catalyzed Biginelli type condensation of aldehydes, beta-keto esters and carbamates: synthesis of 3,4-dihydro[1,3]oxazin-2-ones0 aCuOTf2 catalyzed Biginelli type condensation of aldehydes betake  aANUSANDHAN BHAWAN, 2 RAFI MARG, NEW DELHI, 110001, INDIAbCOUNCIL SCIENTIFIC & INDUSTRIAL REScJUL  a1091-10950 v473 a<p>Cu(OTf)(2) catalyzes effectively a new multicomponent reaction comprising aldehydes, beta-ketoester and methy carbamate in acetonitrile to afford substituted 3,4-dihydro[1,3]oxazin-2-ones in 60-82% yields. These compounds have been found to show inhibition activity against HL-60 cancer cell.</p>10aaldehydes10aCatalysts10aCopper10aMulticomponent reaction1 aJagdale, Arun, R.1 aParaskar, Abhimanyu, S.1 aSudalai, Arumugam  uhttps://library.ncl.res.in/content/cuotf2-catalyzed-biginelli-type-condensation-aldehydes-beta-keto-esters-and-carbamates-001082nas a2200169   4500008004100000022001400041245013100055210006900186260007100255300001200326490000700338520037200345100002200717700002000739700002200759856013100781       2009                        eng d  a1523-706000aAsymmetric synthesis of tetrahydroquinolin-3-ols via CoCl2-catalyzed reductive cyclization of nitro cyclic sulfites with NaBH40 aAsymmetric synthesis of tetrahydroquinolin3ols via CoCl2catalyze  a1155 16TH ST, NW, WASHINGTON, DC 20036 USAbAMER CHEMICAL SOCcFEB  a803-8060 v113 a<p>A new method for the construction of chiral 3-substituted tetrahydroquinoline derivatives based on asymmetric dihydroxylation and CoCl2-catalyzed reductive, cyclization of nitro cyclic sulfites with NaBH4 has been described with high optical purities. This method has been successfully applied in the formal synthesis of PNU 95666E and anachelin H chromophore.</p>1 aJagdale, Arun, R.1 aReddy, Santhosh1 aSudalai, Arumugam  uhttps://library.ncl.res.in/content/asymmetric-synthesis-tetrahydroquinolin-3-ols-cocl2-catalyzed-reductive-cyclization-nitro-001309nas a2200217   4500008004100000022001400041245014200055210006900197260007500266300001200341520047000353653001300823653001100836653001400847653001100861653001500872100002200887700002800909700002200937856013200959       2009                        eng d  a0039-788100aCobalt(II) chloride hexahydrate-diisopropylamine catalyzed mild and chemoselective reduction of carboxylic esters with sodium borohydride0 aCobaltII chloride hexahydratediisopropylamine catalyzed mild and  aRUDIGERSTR 14, D-70469 STUTTGART, GERMANYbGEORG THIEME VERLAG KGcFEB  a660-6643 a<p>The cobalt-catalyzed reduction of unsaturated alpha-cyano carboxylic esters using sodium borohydride (NaBH(4)) leads to the corresponding saturated cyano alcohols in high yields. In particular, the new catalytic system cobalt(II) chloride-diisopropylamine in combination with NaBH(4) showed excellent activity in the chemoselective reduction of a variety of carboxylic esters to their corresponding alcohols in good to excellent yields under mild conditions.</p>10aAlcohols10aamines10acatalysis10aEsters10areductions1 aJagdale, Arun, R.1 aParaskar, Abhimanyu, S.1 aSudalai, Arumugam  uhttps://library.ncl.res.in/content/cobaltii-chloride-hexahydrate-diisopropylamine-catalyzed-mild-and-chemoselective-reduction-001123nas a2200169   4500008004100000022001400041245013200055210006900187260010600256300001200362490000700374520037500381100002200756700002000778700002300798856013200821       2009                        eng d  a0957-416600aConcise enantioselective synthesis of 1-[(S)-3-(dimethylamino)-3,4 dihydro-6,7-dimethoxyquinolin-1(2H)-yl]propan-1-one, (S)-9030 aConcise enantioselective synthesis of 1S3dimethylamino34 dihydro  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcFEB  a335-3390 v203 a<p>A concise enantioselective synthesis of (S)-903, an inotropic agent, is described in nine linear steps and 95% ee based on asymmetric dihydroxylation of cinnamate ester and Co-catalyzed Multifunctional reduction of several functional groups leading to the construction of core tetrahydroquinolin-3-ol, as the key steps. (C) 2009 Elsevier Ltd. All rights reserved.</p>1 aJagdale, Arun, R.1 aReddy, Santhosh1 aSudalai, Arurnugam  uhttps://library.ncl.res.in/content/concise-enantioselective-synthesis-1-s-3-dimethylamino-34-dihydro-67-dimethoxyquinolin-12h-001191nas a2200241   4500008004100000022001400041245012000055210006900175260010300244300001400347490000700361520029300368653001600661653001300677653001700690653001600707653001100723653001500734100002200749700003200771700002200803856012400825       2009                        eng d  a0376-469900aCu(OTf)(2)-catalyzed alpha-halogenation of ketones with 1,3-dichloro-5,5 `-dimethylhydantoin and N-bromosuccinimide0 aCuOTf2catalyzed alphahalogenation of ketones with 13dichloro55 d  aANUSANDHAN BHAWAN, 2 RAFI MARG, NEW DELHI, 110001, INDIAbCOUNCIL SCIENTIFIC & INDUSTRIAL REScOCT  a1424-14300 v483 a<p>Copper(II) triflate catalyses efficiently the alpha-halogentation of aryl or alkyl ketones with 1,3-dichloro-5,5'-dimethyl-hydantoin and N-bromosaccinimde to give the corresponding alpha,alpha-dichloroketones and alpha-bromoketones in high yield with excellent product selectivity.</p>10aBromination10aCatalyst10achlorination10acopper (II)10aKetone10aLewis acid1 aJagdale, Arun, R.1 aChouthaiwale, Pandurang, V.1 aSudalai, Arumugam  uhttps://library.ncl.res.in/content/cuotf2-catalyzed-alpha-halogenation-ketones-13-dichloro-55-dimethylhydantoin-and-n-0