01549nas a2200169   4500008004100000022001400041245015200055210006900207260010600276300001200382490000700394520077900401100002501180700002301205700002401228856012701252       2005                        eng d  a0040-402000aChelation controlled regiospecific O-substitution of myo-inositol orthoesters: convenient access to orthogonally protected myo-inositol derivatives0 aChelation controlled regiospecific Osubstitution of myoinositol   aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcJAN  a529-5360 v613 a<p>A general method for the completely regioselective protection of the three secondary hydroxyl groups of orthoester derivatives of myo-mositol, utilizing the subtle differences in reactivity exhibited by its alkali metal alkoxides due to differences in their ability to form chelates, is described. This method provides convenient access to orthogonally protected myo-inositol derivatives. A comparison of the methylation of racemic 4-0-trityl-myo-inositol 1,3,5-orthoformate in the presence of sodium or lithium ions showed that stabilization of the C4-alkoxide by chelation with lithium overrides steric hindrance offered by the C6-axial substituent in deciding the regioselectivity during the nucleophilic O-substitution. (C) 2004 Elsevier Ltd. All rights reserved.</p>1 aDevaraj, Subramanian1 aShashidhar, M., S.1 aDixit, Shailesh, S.  uhttps://library.ncl.res.in/content/chelation-controlled-regiospecific-o-substitution-myo-inositol-orthoesters-convenient-001273nas a2200169   4500008004100000022001400041245022200055210006900277260011000346300001400456520041200470100002400882700002500906700002300931700001800954856013100972       2005                        eng d  a1359-734500aConcomitant dimorphs of tri-O-[p-halobenzoyl]-myo-inositol 1,3,5-orthoformates with different halogen bonding contacts: first order crystal-to-crystal thermal phase transition of kinetic form to the thermodynamic form0 aConcomitant dimorphs of triOphalobenzoylmyoinositol 135orthoform  aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcOCT  a5870-58723 a<p>Crystallization of tri-O-[p-halobenzoyl]-myo-inositol 1,3,5-orthoformates from ethyl acetate-petroleum ether solution produced concomitant dimorphs that have different halogen bonding contacts; the kinetic form with C-(BrO)-O-...-C contacts upon heating to 185 degrees C, converts completely to the thermodynamic form with C-(BrOLC)-O-... contacts via crystal-to-crystal first order phase transition.</p>1 aGonnade, Rajesh, G.1 aBhadbhade, Mohan, M.1 aShashidhar, M., S.1 aSanki, A., K.  uhttps://library.ncl.res.in/content/concomitant-dimorphs-tri-o-p-halobenzoyl-myo-inositol-135-orthoformates-different-halogen-101734nas a2200241   4500008004100000022001400041245018600055210006900241260010600310300001400416490000700430520077100437653001601208653001301224653001301237653001101250653001201261653001801273100002401291700002301315700002501338856012901363       2006                        eng d  a0040-402000aCyclitol based metal complexing agents. preference for the extraction of lithium by myo-inositol based crown-4-ethers depends on the relative orientation of crown ether oxygen atoms0 aCyclitol based metal complexing agents preference for the extrac  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcMAY  a4360-43630 v623 a<p>myo-Inositol derived crown-4-ethers in which two of the oxygen atoms in the crown ether moiety have different relative orientations were prepared. Metal picrate binding studies revealed that the crown ether having 1,3-diaxial orientation shows the highest selectivity for binding to lithium although the crown ether having 1,2-diequatorial orientation exhibited the highest binding constant for lithium picrate. These results suggest that relative binding affinity of metal ions to crown ethers can be tuned by varying the relative orientation of crown ether oxygen atoms. The relevance of these results to the previously observed regioselectivity during the O-substitution of myo-inositol orthoesters is discussed. (c) 2606 Elsevier Ltd. All rights reserved.</p>10acrown ether10aCyclitol10aInositol10aligand10alithium10ametal complex1 aDixit, Shailesh, S.1 aShashidhar, M., S.1 aDevaraj, Subramanian  uhttps://library.ncl.res.in/content/cyclitol-based-metal-complexing-agents-preference-extraction-lithium-myo-inositol-based-001688nas a2200265   4500008004100000022001400041245010200055210006900157260005700226300001200283490000700295520075000302653001701052653002201069653002501091653001301116653003001129653001701159653003001176100002401206700002401230700002501254700002301279856012001302       2010                        eng d  a0022-476600aConformational polymorphism in racemic 2,4-Di-o-Benzoyl-6-o-Tosyl myo-Inositol 1,3,5-Orthoacetate0 aConformational polymorphism in racemic 24DioBenzoyl6oTosyl myoIn  a233 SPRING ST, NEW YORK, NY 10013 USAbSPRINGERcAUG  a725-7300 v513 a<p>The title compound, C(29)H(26)O(10)S, yields two conformational polymorphs concomitantly from dichloromethane-methanol mixture; the major polymorph grows as plates (Form I, monoclinic, P2(1)/n) and the minor polymorph grows as needles (Form II, triclinic, P-1). The two forms differ mainly in orientation of the tosyl group. In Form I, sulfonyl oxygen of the tosyl group makes intermolecular C -HaEuro broken vertical bar O interactions, whereas the same group in Form II is involved in an intramolecular short dipolar S=OaEuro broken vertical bar C=O (sulfonyl-carbonyl) contact. The molecular organization and the influence of various weak non-covalent interactions that stabilize these conformers in the crystal lattices are discussed.</p>10aConformation10acrystal structure10adipolar interactions10aInositol10anon-covalent interactions10apolymorphism10asulfonyl-carbonyl contact1 aManoj, Kochunnoonny1 aGonnade, Rajesh, G.1 aBhadbhade, Mohan, M.1 aShashidhar, M., S.  uhttps://library.ncl.res.in/content/conformational-polymorphism-racemic-24-di-o-benzoyl-6-o-tosyl-myo-inositol-135-0