01715nas a2200217   4500008004100000022001400041245012600055210006900181260011000250300001400360490000600374520083200380100002301212700001801235700002701253700002101280700002201301700001701323700003001340856012701370       2011                        eng d  a2040-336400aSilver nanoparticle studded porous polyethylene scaffolds: bacteria struggle to grow on them while mammalian cells thrive0 aSilver nanoparticle studded porous polyethylene scaffolds bacter  aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcJUN  a2957-29630 v33 a<p>Silver nanoparticle studded scaffolds were prepared by exploiting the Ag+ ion reducing activity of sophorolipids-a class of `glycolipids' that cap the ensuing nanoparticles as well. To achieve this, the porous polyethylene scaffolds are subjected to N-2+H-2 plasma treatment, in the first step. Subsequently the sophorolipids are covalently attached to the amine groups on the polymer surface through simple amide chemistry to yield sophorolipid grafted polymer scaffolds. These are then exposed to Ag+ ions under appropriate conditions leading to the formation of silver nanoparticles immobilized on the polymer scaffolds. It has been found that while bacteria do not survive on these silver studded scaffolds, CHO-K1 cells thrive on them making them good candidates for tissue engineering and bio-implant applications.</p>1 aD'Britto, Virginia1 aKapse, Harsha1 aBabrekar, Harshada, A.1 aPrabhune, Asmita1 aBhoraskar, S., V.1 aPremnath, V.1 aPrasad, Bhagavatula L. V.  uhttps://library.ncl.res.in/content/silver-nanoparticle-studded-porous-polyethylene-scaffolds-bacteria-struggle-grow-them-0