01684nas a2200277   4500008004100000022001400041245016300055210006900218260010600287300001400393490000700407520057500414653002400989653003101013653002801044653003101072653002101103100002101124700002001145700001901165700001801184700002301202700002601225700002601251856012901277       2007                        eng d  a0968-089600aSynthesis and evaluation of antifungal properties of a series of the novel 2-amino-5-oxo-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile and its analogues0 aSynthesis and evaluation of antifungal properties of a series of  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcNOV  a6705-67150 v153 a<p>A series of 2-amino-5-oxo-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile and various analogues have been synthesized in excellent isolated yields starting from various arylidenemalononitrile and 3-amino-2-cyclohexen-1-one in 1-propanol as solvent at reflux temperature in the absence of any added catalyst. All the synthesized compounds were evaluated for their antifungal activity. The relationship between functional group variation and biological activity of the evaluated compounds is discussed in the article. (C) 2007 Elsevier Ltd. All rights reserved.</p>10aAntifungal activity10aantiproliferative activity10aarylidenemalononitriles10aarylquinoline carbonitrile10aMichael addition1 aGholap, Atul, R.1 aToti, Kiran, S.1 aShirazi, Fazal1 aKumari, Ratna1 aBhat, Manoj, Kumar1 aDeshpande, Mukund, V.1 aSrinivasan, Kumar, V.  uhttps://library.ncl.res.in/content/synthesis-and-evaluation-antifungal-properties-series-novel-2-amino-5-oxo-4-phenyl-5678-001503nas a2200265   4500008004100000022001400041245012700055210006900182260010300251300001400354490000700368520047800375653002700853653002400880653002200904653002300926653002200949100002600971700002200997700002401019700002201043700001901065700002601084856012701110       2011                        eng d  a0223-523400aStereoselective synthesis and antimicrobial activity of steroidal C-20 tertiary alcohols with thiazole/pyridine side chain0 aStereoselective synthesis and antimicrobial activity of steroida  a23 RUE LINOIS, 75724 PARIS, FRANCEbELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIERcSEP  a3681-36890 v463 a<p>Stereoselective synthesis of novel steroidal C-20 tertiary alcohols with thiazole and pyridine side chain using Grignard reaction of steroidal ketones and thiazole/pyridine magnesium bromide have been realized. These molecules were evaluated in vitro for their antifungal and antibacterial activities. Most of the compounds exhibited significant antifungal and antibacterial activity against all the tested strains. (C) 2011 Elsevier Masson SAS. All rights reserved.</p>10aantibacterial activity10aAntifungal activity10aGrignard reaction10aSteroid side chain10aSteroidal ketones1 aShingate, Bapurao, B.1 aLiazra, Braja, G.1 aSalunke, Deepak, B.1 aPore, Vandana, S.1 aShirazi, Fazal1 aDeshpande, Mukund, V.  uhttps://library.ncl.res.in/content/stereoselective-synthesis-and-antimicrobial-activity-steroidal-c-20-tertiary-alcohols-001309nas a2200265   4500008004100000022001400041245007700055210006900132260010600201300001600307490000700323520035200330653002200682653002700704653002400731653002000755653002400775100002600799700002100825700002400846700002200870700001900892700002600911856010600937       2013                        eng d  a0040-402000aSynthesis and antimicrobial activity of novel oxysterols from lanosterol0 aSynthesis and antimicrobial activity of novel oxysterols from la  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcDEC  a11155-111630 v693 a<p>Chemically diverse oxysterols and their synthetic manipulations were carried out from variety of Delta(8(9)_) lanosterol derivatives and evaluated for their in vitro antimicrobial activities. Most of the synthesized oxysterols exhibited significant antifungal activity against the tested strains. (C) 2013 Elsevier Ltd. All rights reserved.</p>10aAllylic oxidation10aantibacterial activity10aAntifungal activity10aDihydroxylation10aOxygenated steroids1 aShingate, Bapurao, B.1 aHazra, Braja, G.1 aSalunke, Deepak, B.1 aPore, Vandana, S.1 aShirazi, Fazal1 aDeshpande, Mukund, V.  uhttps://library.ncl.res.in/content/synthesis-and-antimicrobial-activity-novel-oxysterols-lanosterol-0