02117nas a2200253   4500008004100000022001400041245010700055210006900162260006900231300001200300490000800312520124100320653001201561653001801573653002301591653001601614100001801630700001901648700001801667700001601685700001701701700001901718856012601737       2011                        eng d  a0254-058400aSynthesis and characterization of CdS/PVA nanocomposite thin films from a complexing agent free system0 aSynthesis and characterization of CdSPVA nanocomposite thin film  aPO BOX 564, 1001 LAUSANNE, SWITZERLANDbELSEVIER SCIENCE SAcDEC  a223-2290 v1313 a<p>CdS/PVA nanocomposite thin films have been deposited on glass substrates by in situ thermolysis of precursors dispersed in polyvinyl alcohol (PVA). The synthetic technique reported in this study is free from complexing agent and hence no need to control the pH of the solution as in the case of conventional CBD. The as-prepared films were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), selected area electron diffraction (SAED), UV-vis spectroscopy, and photoluminescence (PL) spectra. The XRD and SAED results indicated the formation of CdS nanoparticles with hexagonal phase in the PVA matrix. The photoluminescence and UV-vis spectroscopy revealed that CdS/PVA films showed quantum confinement effect. From the shift in optical band gap, particle sizes were calculated using effective mass approximation (EMA) method and it was found to be in agreement with the results obtained from TEM observations. The SEM results indicated that as grown films were homogeneous with no visible pinholes and cracks. The film prepared at 100 degrees C was found to be suitable for application as a window layer in solar cell. (C) 2011 Elsevier B.V. All rights reserved.</p>10aCdS/PVA10aNanocomposite10aOptical properties10aThermolysis1 aSaikia, Dulen1 aSaikia, P., K.1 aGogoi, P., K.1 aDas, M., R.1 aSengupta, P.1 aShelke, M., V.  uhttps://library.ncl.res.in/content/synthesis-and-characterization-cdspva-nanocomposite-thin-films-complexing-agent-free-001805nas a2200193   4500008004100000022001400041245009300055210007100148260000900219300001600228490000600244520115600250100001401406700001801420700001501438700001701453700001301470856012801483       2018                        eng d  a2470-134300aImpairing powerhouse in colon cancer cells by hydrazide–hydrazone-based small molecule0 aImpairing powerhouse in colon cancer cells by hydrazide–hydrazon  cFEB   a1470–14810 v33 aMitochondrion has emerged as one of the unconventional targets in next-generation cancer therapy. Hence, small molecules targeting mitochondria in cancer cells have immense potential in the next-generation anticancer therapeutics. In this report, we have synthesized a library of hydrazide–hydrazone-based small molecules and identified a novel compound that induces mitochondrial outer membrane permeabilization by inhibiting antiapoptotic B-cell CLL/lymphoma 2 (Bcl-2) family proteins followed by sequestration of proapoptotic cytochrome c. The new small molecule triggered programmed cell death (early and late apoptosis) through cell cycle arrest in the G2/M phase and caspase-9/3 cleavage in HCT-116 colon cancer cells, confirmed by an array of fluorescence confocal microscopy, cell sorting, and immunoblotting analysis. Furthermore, cell viability studies have verified that the small molecule rendered toxicity to a panel of colon cancer cells (HCT-116, DLD-1, and SW-620), keeping healthy L929 fibroblast cells unharmed. The novel small molecule has the potential to form a new understudied class of mitochondria targeting anticancer agent.1 aPatil, S.1 aKuman, M., M.1 aPalvai, S.1 aSengupta, P.1 aBasu, S.  uhttps://library.ncl.res.in/content/impairing-powerhouse-colon-cancer-cells-hydrazide%E2%80%93hydrazone-based-small-molecule01223nas a2200157   4500008004100000245008800041210006900129260000800198300001000206490000700216520067000223100001700893700002000910700001900930856011600949       2018                        eng d00aModification of porous polyethylene scaffolds for cell attachment and proliferation0 aModification of porous polyethylene scaffolds for cell attachmen  cMAR  a87-900 v133 a<p>Synthetic polymers are widely researched for their use in tissue engineering. Control in size, surface area, pore size, and elasticity are the biggest advantages of using a man-made polymer. However, often the polymers are hydrophobic (do not encourage cell attachment); hence, it is hugely challenging to integrate them with the normal tissues. Herein, we have tried to overcome this disadvantage of polymers by coating them with citrate-stabilized gold nanoparticles and arginine. High-density polyethylene, upon multiple treatments, shows low water contact angle, which encourages cell attachment and proliferation in comparison to the untreated polymers.</p>1 aSengupta, P.1 aSurwase, S., S.1 aPrasad, B., L.  uhttps://library.ncl.res.in/content/modification-porous-polyethylene-scaffolds-cell-attachment-and-proliferation